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Cogan Derek, Hao Ming Hong, Kamhi Victor Marc, Miller Craig Andrew, Netherton Matthew Russell, Swinamer Alan David: 3-‘4-heterocyclyl -1,2,3,-triazol-1-yl!-n-aryl-benzamides as inhibitors of the cytokines production for the treatment of chronic inflammatory diseases. Boehringer Ingelheim Pharmaceuticals, Cogan Derek, Hao Ming Hong, Kamhi Victor Marc, Miller Craig Andrew, Netherton Matthew Russell, Swinamer Alan David, MORRIS Michael P, September 29, 2005: WO/2005/090333 (8 worldwide citation)

Disclosed compounds of formula (I), which inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds a ...


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Cogan Derek, Hao Ming Hong, Aungst Ronald A, Swinamer Alan David: Anti-cytokine heterocyclic compounds. Boehringer Ingelheim Pharmaceuticals, Cogan Derek, Hao Ming Hong, Aungst Ronald A, Swinamer Alan David, MORRIS Michael P, December 8, 2005: WO/2005/115991 (7 worldwide citation)

Disclosed are compunds of formula (I). The compounds inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these ...


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Cogan Derek A, Hao Ming Hong, Qian Kevin Chungeng, Swinamer Alan D: 1, 2, 3- triazole amide derivatives as cytokine inhibitors. Boehringer Ingelheim Pharmaceuticals, RAYMOND Robert P, June 17, 2004: WO/2004/050642 (3 worldwide citation)

Disclosed are compounds of formula (I). Where Ar1, X, R3, R4, R5 and R6 are defined herein. The compounds of the invention inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic i ...


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Cogan Derek, Hao Ming Hong, Kamhi Victor Marc, Miller Craig A, Netherton M R, Swinamer Alan D: 3-[4-heterocyclyl-1,2,3-triazol-1-yl]-n-aryl-benzamides as inhibitors of the cytokines production for the treatment of chronic inflammatory diseases. Boehringer Ingelheim Pharma, November 29, 2006: EP1725544-A1 (2 worldwide citation)

Disclosed compounds of formula (I), which inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds a ...


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Breitfelder Steffen, Cirillo Pier F, Hao Ming Hong, Hickey Eugene R, Sharma Rajiv, Sun Sanxing, Takahashi Hidenori: Urea derivatives as anti-inflammatory agents. Boehringer Ingelheim Pharmaceuticals, Breitfelder Steffen, Cirillo Pier F, Hao Ming Hong, Hickey Eugene R, Sharma Rajiv, Sun Sanxing, Takahashi Hidenori, RAYMOND Robert, May 25, 2001: WO/2001/036403 (2 worldwide citation)

Disclosed are novel aromatic compounds of formula (I) wherein G, X, Ar, L and Q are defined herein. The compounds are useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are processes of mak ...


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Cogan Derek, Goldberg Daniel R, Hao Ming Hong, Xiong Zhaoming, Aungst Ronald A, Davis Amy L: Cytokine inhibitors. Boehringer Ingelheim Pharmaceuticals, Cogan Derek, Goldberg Daniel R, Hao Ming Hong, Xiong Zhaoming, Aungst Ronald A, Davis Amy L, MORRIS Michael P, November 17, 2005: WO/2005/108387 (1 worldwide citation)

Disclosed are compounds of formula (I) which inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compound ...


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Cywin Charles L, Chen Zhidong, Emeigh Jonathan, Fleck Roman Wolfgang, Hao Ming Hong, Hickey Eugene, Liu Weimin, Marshall Daniel Richard, Morwick Tina, Nemoto Peter, Sorcek Ronald John, Sun Sanxing, Wu Jiang Ping: 3-amino-thieno[2,3-b]pyridine-2-carboxylic acid amides. Boehringer Ingelheim Pharma, December 31, 2008: EP2008654-A1

Disclosed are compounds of formula (I): wherein R 1 and R 2 are defined herein, which are useful as inhibitors of the kinase activity of the I B kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases and ...


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Cogan Derek, Hao Ming Hong, Kahmi Victor, Miller Craig Andrew, Netherton Matthew Russell, Swinamer Alan David: 3-[4-heterocyclyl -1,2,3-triazol-1-yl]-n-aryl-benzamides as inhibitors of the cytokines production for the treatment of chronic inflammatory diseases. Boehringer Ingelheim Pharma, February 13, 2008: EP1887003-A1

Disclosed compounds of formula (I) which inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds an ...