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Khire Uday, Liu Xiao Gao, Nagarathnam Dhanapalan, Wood Jill, Wang Lei, Liu Donglei, Zhao Jin, Guernon Leatte, Zhang Lei: Quinolone carboxylic acid derivatives for treatment of hyperproliferative conditions. Bayer Pharmaceuticals Corporation, Khire Uday, Liu Xiao Gao, Nagarathnam Dhanapalan, Wood Jill, Wang Lei, Liu Donglei, Zhao Jin, Guernon Leatte, Zhang Lei, GREENMAN Jeffrey M, October 20, 2005: WO/2005/097752 (1 worldwide citation)

Quinolone carboxylic acid derivatives of formula (I) wherein Ar is an optionally substituted phenyl, pyridyl, or pyrimidinyl group and the substituent groups R1, R4, R10, R11, R19, and R20 are as defined in the specification, pharmaceutical compositions containing them, and methods of using them in ...


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Henteman Martin F, Scott William, Wood Jill, Johnson Jeffrey, Redman Aniko, Bullion Ann Marie, Guernon Leatte: Sulfone substituted 2,3-dihydroimidazo [1,2-c] quinazoline derivatives useful for treating hyper-proliferative disorders and diseases with angiogenesis. Bayer Healthcare, Henteman Martin F, Scott William, Wood Jill, Johnson Jeffrey, Redman Aniko, Bullion Ann Marie, Guernon Leatte, LOREN Ralph A, July 23, 2009: WO/2009/091550 (1 worldwide citation)

This invention relates to novel sulfone 2I3-dihydroimidazo[1 l2-c]quinazoline compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for phosphotidylinositol-3-kinase (PI3K) inhibition and treating diseases associated with phosphotidylinositol ...


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Khire Uday, Liu Xiao Gao, Nagarathnam Dhanapalan, Wood Jill, Wang Lei, Liu Donglei, Zhao Jin, Guernon Leatte, Zhang Lei: Quinolone carboxylic acid derivatives for treatment of hyperproliferative conditions. Bayer Pharmaceuticals, December 20, 2006: EP1732897-A1

Quinolone carboxylic acid derivatives of formula (I) wherein Ar is an optionally substituted phenyl, pyridyl, or pyrimidinyl group and the substituent groups R1, R4, R10, R11, R19, and R20 are as defined in the specification, pharmaceutical compositions containing them, and methods of using them in ...


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Dumas Jacques, Sibley Robert, Smith Roger, Su Ning, Chen Yuanwei, Wood Jill, Guernon Leatte, Dixon Julie, Brennan Catherine, Boyer Stephen: Quinazoline and quinoline derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents. Bayer Pharmaceuticals Corporation, Dumas Jacques, Sibley Robert, Smith Roger, Su Ning, Chen Yuanwei, Wood Jill, Guernon Leatte, Dixon Julie, Brennan Catherine, Boyer Stephen, GREENMAN Jeffrey M, July 10, 2003: WO/2003/055866

Quinazoline or quinoline derivatives of formula: (Formula I and II); wherein Z is CH or N; Y is O or S; X is OR5 or NR5R6; R1, R2, R3, R4, R5 and R6 are as disclosed. Also described is a method for the inhibiting the prolyl peptidase, inducing apoptosis and treating cancer ...


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