1
Gregory T Zugates, Andreas Zumbuehl, Robert S Langer, Daniel G Anderson: End-modified poly(beta-amino esters) and uses thereof. Massachusetts Institute of Technology, Wolf Greenfield & Sacks P C, C Hunter Baker, Robin A Weatherhead, December 6, 2011: US08071082 (25 worldwide citation)

Poly(beta-amino esters) are end-modified to form materials useful in the medical as well as non-medical field. An amine-terminated poly(beta-amino ester) is reacted with an electrophile, or an acrylate-terminated poly(beta-amino ester) is reacted with a nucleophile. The inventive end-modified polyme ...


2
Gregory T Zugates, Andreas Zumbuehl, Robert S Langer, Daniel Griffith Anderson: End-modified poly(beta-amino esters) and uses thereof. Massachusetts Institute of Technology, Wolf Greenfield & Sacks P C, C Hunter Baker, October 22, 2013: US08562966 (19 worldwide citation)

Poly(beta-amino esters) are end-modified to form materials useful in the medical as well as non-medical field. An amine-terminated poly(beta-amino ester) is reacted with an electrophile, or an acrylate-terminated poly(beta-amino ester) is reacted with a nucleophile. The inventive end-modified polyme ...


3
Maria Palasis, Changcheng You, Daniel Concagh, Lee Core, Kicherl Ho, Upma Sharma, Gregory T Zugates: Medical implants. 480 Biomedical, Kacvinsky Daisak Bluni PLLC, March 31, 2015: US08992601

Disclosed are self-expanding medical implants for placement within a lumen of a patient. The implants comprise a woven or non-woven structure having a substantially tubular configuration, and are designed to be low-profile such that they are deliverable with a small diameter catheter. The implants h ...


4
Maria Palasis, Changcheng You, Danny Concagh, Lee Core, Kicherl Ho, Upma Sharma, Gregory T Zugates: Drug eluting medical implant. 480 BIOMEDICAL, Kacvinsky Daisak Bluni PLLC, October 13, 2015: US09155638

Disclosed are self-expanding medical implants for placement within a lumen of a patient. The implants comprise a woven or non-woven structure having a substantially tubular configuration, and are designed to be low-profile such that they are deliverable with a small diameter catheter. The implants h ...


5
Upma Sharma, Irina Gitlin, Gregory T Zugates, Adam Rago, Parisa Zamiri, Rany Busold, Toby Freyman, Robert J Caulkins, Quynh P Pham, Changcheng You, Jeffrey D Carbeck: In situ forming hemostatic foam implants. Arsenal Medical, Kacvinsky Daisak Bluni PLLC, November 3, 2015: US09173817

Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, ...


6
Toby Freyman, Joseph Lomakin, John Marini, Jennifer Mortensen, Adam Rago, Rany Busold, Upma Sharma, Gregory T Zugates: In-situ forming foams with outer layer. Arsenal Medical, Kacvinsky Daisak Bluni PLLC, June 2, 2015: US09044580

Systems, methods and kits relating to in-situ forming polymer foams for the treatment of aneurysms or fluid filled spaces are disclosed. The systems include an insertable medical device and an in-situ forming foam of lava like materials with a fast forming outer skin and a slower hardening interior ...


7
Maria Palasis, Changcheng You, Danny Concagh, Lee Core, Kicherl Ho, Upma Sharma, Gregory T Zugates: Drug-eluting medical implants. Arsenal Medical, August 22, 2017: US09737647

Disclosed are self-expanding medical implants for placement within a lumen of a patient. The implants comprise a woven or non-woven structure having a substantially tubular configuration, and are designed to be low-profile such that they are deliverable with a small diameter catheter. The implants h ...


8
Maria Palasis, Changcheng You, Danny Concagh, Lee Core, Kicherl Ho, Upma Sharma, Gregory T Zugates: Drug-eluting medical implants. 480 BIOMEDICAL, Medlen & Carroll, March 6, 2018: US09907886

Disclosed are self-expanding medical implants for placement within a lumen of a patient. The implants comprise a woven or non-woven structure having a substantially tubular configuration, and are designed to be low-profile such that they are deliverable with a small diameter catheter. The implants h ...


9
Gregory T Zugates, Adam Rago, Toby Freyman, Upma Sharma, Rany Busold, John Caulkins, Parisa Zamiri, Jennifer Mortensen, Meghan McGill, Daniel K Bonner: Foam-based medical treatments. ARSENAL MEDICAL, April 18, 2017: US09623143

The present invention relates generally to systems and methods and systems for generating polymer foams within body cavities to locate and/or control bleeding. The present invention further relates to methods and systems for generating polymer foams within non-compressible wounds to control or stop ...


10
Adam Rago, John Marini, Gregory T Zugates, Marc Helmick, Upma Sharma: Intra-abdominal pressure to promote hemostasis and survival. ARSENAL MEDICAL, November 21, 2017: US09820749

Systems, methods and kits for treating hemorrhages within cavities are provided. The methods utilize the application of a rapid spike of pressure to the closed cavity, followed by a steady state pressure or pressures.