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Gregory T A Kovacs, Terry R Knapp: Implantable biosensing transponder. LipoMatrix, Howell & Haferkamp L C, November 10, 1998: US05833603 (970 worldwide citation)

A biosensing transponder for implantation in an organism including a human comprises a biosensor for sensing one or more physical properties related to the organism after the device has been implanted, including optical, mechanical, chemical, and electrochemical properties, and a transponder for wir ...


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Gregory T A Kovacs: Multiplexed active biologic array. Nanogen, Lyon & Lyon, October 12, 1999: US05965452 (267 worldwide citation)

An improved biologic electrode array and methods for manufacturing and using the same. In one aspect, a matrix of electrodes each coupled to a respective sample-and-hold circuit is provided. The electrodes and sample-and-hold circuits are integral and form an array within a single semiconductor chip ...


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Lee Allan Christel, Gregory T A Kovacs, William A McMillan, M Allen Northrup, Kurt E Petersen, Farzad Pourahmadi: Non-planar microstructures for manipulation of fluid samples. Cepheid, Heller Ehrman White & McAuliffe, April 9, 2002: US06368871 (257 worldwide citation)

This invention comprises an apparatus and method for the manipulation of materials, including particles, cells, macromolecules, such as proteins, nucleic acids and other moieties, in fluid samples. The apparatus comprises an enclosed chamber on a chip having an internal microstructure with surface a ...


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Farzad Pourahmadi, William A McMillan, Jesus Ching, Ronald Chang, Lee A Christel, Gregory T A Kovacs, M Allen Northrup, Kurt E Petersen: Device incorporating a microfluidic chip for separating analyte from a sample. Cepheid, Townsend and Townsend and Crew, December 16, 2003: US06664104 (250 worldwide citation)

A device for separating an analyte from a fluid sample comprises a cartridge incorporating a flow-through microfluidic chip. The microfluidic chip includes an extraction chamber having an array of microstructures for capturing the analyte and for subsequently releasing the captured analyte into an e ...


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Kurt E Petersen, William A McMillan, Lee A Christel, Ronald Chang, Farzad Pourahmadi, Jesus Ching, Gregory T A Kovacs, M Allen Northrup: Method for separating analyte from a sample. Cepheid, Townsend and Townsend and Crew, May 17, 2005: US06893879 (188 worldwide citation)

An analyte is separated from a fluid sample by introducing the sample into a cartridge having an extraction chamber containing capture material for capturing the analyte. The sample is forced to flow through the extraction chamber to capture the analyte with the capture material in the extraction ch ...


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Kurt Petersen, Gregory T A Kovacs, Terence G Ryan, Leon G Partamian, David A Lee: Implantable continuous intraocular pressure sensor. Lumen Intellectual Property Services, September 6, 2005: US06939299 (179 worldwide citation)

An implantable miniaturized pressure sensor integrates a capacitor and an inductor in one small chip, forming a resonant LC circuit having a Q value of 10 or greater. The capacitor has an upper capacitor plate and a lower capacitor plate disposed proximate thereof. The upper and lower capacitor plat ...


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Gregory T A Kovacs, David A Borkholder: Hybrid biosensors. Board of Trustees Leland Stanford Jr University, Coudert Brothers, November 9, 1999: US05981268 (157 worldwide citation)

The invention relates to an apparatus and method for monitoring cells and to a method for monitoring changes in cells upon addition of an analyte to the cell's environment, comprising a device which includes an array of microelectrodes disposed in a cell culture chamber, upon which array a portion o ...


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Gregory T A Kovacs: Biologic electrode array with integrated optical detector. Nanogen, O Melveny & Myers, May 16, 2006: US07045097 (141 worldwide citation)

A biologic electrode array is formed on a semiconductor substrate. A matrix of electrode sites is disposed on the semiconductor substrate. A matrix of optical detectors is disposed beneath the electrode sites in the semiconductor substrate, wherein each electrode site is associated with a correspond ...


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Gregory T A Kovacs, David A Borkholder: Hybrid biosensors. Board of Trustees Leland Stanford Jr University, Coudert Brothers, April 18, 2000: US06051422 (134 worldwide citation)

The invention relates to an apparatus and method for monitoring cells and to a method for monitoring changes in cells upon addition of an analyte to the cell's environment, comprising a device which includes an array of microelectrodes disposed in a cell culture chamber, upon which array a portion o ...