1
Hugh A O Hill, Irving J Higgins, James M McCann, Graham Davis: Strip electrode including screen printing of a single layer. MediSense, Fish & Richardson, April 23, 1996: US05509410 (747 worldwide citation)

A sensor system that detects a current representative of a compound in a liquid mixture features a two-electrode strip adapted for releasable attachment to signal readout circuitry. The strip comprises an elongated support (preferably flat) adapted for releasable attachment to the readout circuitry; ...


2
Stephen N Cozzette, Graham Davis, Jeanne A Itak, Imants R Lauks, Randall M Mier, Sylvia Piznik, Nicolaas Smit, Susan J Steiner, Paul Van Der Werf, Henry J Wieck: Wholly microfabricated biosensors and process for the manufacture and use thereof. I Stat Corporation, Pennie & Edmonds, April 6, 1993: US05200051 (651 worldwide citation)

An efficient method for the microfabrication of electronic devices which have been adapted for the analyses of biologically significant analyte species is described. The techniques of the present invention allow for close control over the dimensional features of the various components and layers est ...


3
Hugh Allen Oliver Hill, Irving John Higgins, James Michael McCann, Graham Davis: Strip electrode with screen printing. October 13, 1998: US05820551 (552 worldwide citation)

A sensor system that detects a current representative of a compound in a liquid mixture features a two-electrode strip adapted for releasable attachment to signal readout circuitry. The strip comprises an elongated support (preferably flat) adapted for releasable attachment to the readout circuitry; ...


4
Hugh Allen Oliver Hill, Irving John Higgins, James Michael McCann, Graham Davis: Strip electrode with screen printing. MediSense, Fish & Richardson P C, November 4, 1997: US05682884 (503 worldwide citation)

A sensor system that detects a current representative of a compound in a liquid mixture features a two-electrode strip adapted for releasable attachment to signal readout circuitry. The strip comprises an elongated support (preferably flat) adapted for releasable attachment to the readout circuitry; ...


5
Stephen N Cozzette, Graham Davis, Jeanne Itak, Imants R Lauks, Randall M Mier, Sylvia Piznik, Nicolaas Smit, Susan Steiner, Paul Van Der Werf, Henry J Wieck: Method of manufacturing a plurality of uniform microfabricated sensing devices having an immobilized ligand receptor. I Stat Corporation, Pennie & Edmonds, November 5, 1991: US05063081 (500 worldwide citation)

A plurality of uniform microfabricated sensing devices are produced by establishing a plurality of base sensors on a substrate wafer, forming over at least a portion of each base sensor a permselective layer, superimposing a photoformable proteinaceous photoresist layer over a substantial portion of ...


6
Hugh Allen Oliver Hill, Irving John Higgins, James Michael McCann, Graham Davis: Strip electrode with screen printing. MediSense, Fish & Richardson P C, March 17, 1998: US05727548 (444 worldwide citation)

A sensor system that detects a current representative of a compound in a liquid mixture features a two-electrode strip adapted for releasable attachment to signal readout circuitry. The strip comprises an elongated support (preferably flat) adapted for releasable attachment to the readout circuitry; ...


7
Graham Davis, Hugh A O Hill: Assay systems using more than one enzyme. Genetics International, July 19, 1988: US04758323 (396 worldwide citation)

This specification discloses methods of detection or measurement of an enzyme or of its specific substrate, and sensors used in such methods. The present invention is concerned with a multi-enzyme system, and the specification discloses, as one aspect of the invention a method of assay in which an e ...


8
Stephen N Cozzette, Graham Davis, Imants R Lauks, Randall M Mier deceased, Sylvia Piznik, Nicolaas Smit, Paul Van Der Werf, Henry J Wieck, Susan Steiner, Jeanne Itak: Process for the manufacture of wholly microfabricated biosensors. i STAT Corporation, Pennie & Edmonds, November 17, 1998: US05837454 (356 worldwide citation)

An efficient method for the microfabrication of electronic devices which have been adapted for the analyses of biologically significant analyte species is described. The techniques of the present invention allow for close control over the dimensional features of the various components and layers est ...


9
Stephen N Cozzette, Graham Davis, Imants R Lauks, Randall M Mier, Sylvia Piznik, Nicolaas Smit, Paul Van Der Werf, Henry J Wieck: Process for the manufacture of wholly microfabricated biosensors. i Stat Corporation, Pennie & Edmonds, September 10, 1996: US05554339 (303 worldwide citation)

An efficient method for the microfabrication of electronic devices which have been adapted for the analyses of biologically significant analyte species is described. The techniques of the present invention allow for close control over the dimensional features of the various components and layers est ...


10
Graham Davis, Chao Lin, Imants R Lauks, Raymond J Pierce: Microfabricated aperture-based sensor. i Stat Corporation, Gilberto M Pepper Hamilton Villacorta, February 29, 2000: US06030827 (288 worldwide citation)

A chemical sensor includes an enzyme layer, a diffusion layer and an analyte barrier layer positioned over the diffusion layer. Apertures are formed by microfabrication in the analyte barrier layer to allow controlled analyte flux to the diffusion layer.