1
Deborah A Eppstein, Philip L Felgner, Thomas R Gadek, Gordon H Jones, Richard B Roman: N[.omega.,(.omega.-1)-dialkyloxy]- and N-[.omega.,(.omega.-1)-dialkenyloxy]-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor. Syntex, David A Lowin, Tom M Moran, January 30, 1990: US04897355 (372 worldwide citation)

This invention relates to compounds of the formula ##STR1## or an optical isomer thereof wherein R.sup.1 and R.sup.2 are the same or different and are an alkyl or alkenyl group of 6 to 24 carbon atoms; R.sup.3, R.sup.4 and R.sup.5 are the same or different and are alkyl of 1 to 8 carbon atoms, aryl, ...


2
Deborah A Eppstein, Philip L Felgner, Thomas R Gadek, Gordon H Jones, Richard B Roman: N-(.omega.,(.omega.-1)-dialkyloxy)- and N-(.omega.,(.omega.-1)-dialkenyloxy)-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor. Syntex, David A Lowin, Tom M Moran, August 7, 1990: US04946787 (161 worldwide citation)

This invention relates to compounds of the formula ##STR1## or an optical isomer thereof wherein R.sup.1 and R.sup.2 are the same or different and are an alkyl or alkenyl group of 6 to 24 carbon atoms; R.sup.3, R.sup.4 and R.sup.5 are the same or different and are alkyl of 1 to 8 carbon atoms, aryl, ...


3
Deborah A Eppstein, Philip L Felgner, Thomas R Gadek, Gordon H Jones, Richard B Roman: N-(.omega., (.omega.-1)-dialkyloxy)- and N-(.omega., (.omega.-1)-dialkenyloxy)-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor. Syntex, David A Lowin, Tom M Moran, May 4, 1993: US05208036 (132 worldwide citation)

This invention relates to compounds of the formula ##STR1## or an optical isomer thereof wherein R.sup.1 and R.sup.2 are the same or different and are an alkyl or alkenyl group of 6 to 24 carbon atoms; R.sup.3, R.sup.4 and R.sup.5 are the same or different and are alkyl of 1 to 8 carbon atoms, aryl, ...


4
Deborah A Eppstein, Philip L Felgner, Thomas R Gadek, Gordon H Jones, Richard B Roman: N-.omega.,(.omega.-1)-dialkyloxy)- and N-(.omega.,(.omega.-1)-dialkenyloxy)Alk-1-YL-N,N,N-tetrasubstituted ammonium lipids and uses therefor. Syntex, David A Lowin, Tom M Moran, September 17, 1991: US05049386 (106 worldwide citation)

This invention relates to compounds of the formula ##STR1## or an optical isomer thereof wherein R.sup.1 and R.sup.2 are the same or different and are an alkyl or alkenyl group of 6 to 24 carbon atoms; R.sup.3, R.sup.4 and R.sup.5 are the same or different and are alkyl of 1 to 8 carbon atoms, aryl, ...


5
Deborah A Eppstein, Philip L Felgner, Thomas R Gadek, Gordon H Jones, Richard B Roman: N-[1, (1-1)-dialkyloxy]-and N-[1, (1-1)-dialkenyloxy]-alk-1-yl-n,n,n-tetrasubstituted ammonium lipids and uses therefor. Syntex, Heller Ehrman White & McAuliffe, August 13, 1996: US05545412 (74 worldwide citation)

This invention relates to compounds of the formula ##STR1## or an optical isomer thereof wherein R.sup.1 and R.sup.2 are the same or different and are an alkyl or alkenyl group of 6 to 24 carbon atoms; R.sup.3, R.sup.4 and R.sup.5 are the same or different and are alkyl of 1 to 8 carbon atoms, aryl, ...


6

7
Gordon H Jones, John G Moffatt, John J Nestor Jr: Novel immunological adjuvant compounds and methods of preparation thereof. Syntex, Gerard A Blaufarb, April 4, 1978: US04082736 (50 worldwide citation)

This application relates to novel immunological adjuvant compounds of the formula: ##STR1## wherein each of R and R.sup.1 are the same or different and are hydrogen or an acyl radical; R.sup.2 is an unsubstituted or substituted alkyl radical, or an unsubstituted or substituted aryl radical; R.sup.6 ...


8
Gordon H Jones, John G Moffatt, John J Nestor Jr: Novel immunological adjuvant compounds and methods of preparation thereof. Syntex, Gerard A Blaufarb, April 4, 1978: US04082735 (47 worldwide citation)

This application relates to novel immunological adjuvant compounds of the formula: ##STR1## wherein each of R and R.sup.1 are the same or different and are hydrogen or an acyl radical; R.sup.2 is an unsubstituted or substituted alkyl radical, or an unsubstituted or substituted aryl radical; X is an ...


9
Deborah A Eppstein, Philip L Felgner, Thomas R Gadek, Gordon H Jones, Richard B Roman: N-(1,(1-1)-dialkyloxy)-and N-(1,(1-1)-dialkenyloxy alk-1-yl-N-N,N-tetrasubstituted ammonium lipids and uses therefor. Syntex, Heller Ehrman White & McAuliffe, August 27, 1996: US05550289 (31 worldwide citation)

This invention relates to compounds of the formula ##STR1## or an optical isomer thereof wherein R.sup.1 and R.sup.2 are the same or different and are an alkyl or alkenyl group of 6 to 24 carbon atoms; R.sup.3, R.sup.4 and R.sup.5 are the same or different and are alkyl of 1 to 8 carbon atoms, aryl, ...


10
John J Nestor, Gordon H Jones, Brian H Vickery: Nonapeptide and decapeptide analogs of LHRH, useful as LHRH antagonists. Syntex, Kate H Murashige, Alan M Krubiner, Tom M Moran, July 27, 1982: US04341767 (30 worldwide citation)

Nonapeptide and decapeptide analogs of LHRH which have the formula: ##STR1## and the pharmaceutically acceptable salts thereof, wherein: X is a D-alanyl residue wherein one hydrogen on C-3 is replaced by: