George Tuszynski (1 - 6 of 6 results)


1
Alan H Deutch, George Tuszynski: Peptide fragments and analogs of thrombospondin and methods of use. W R Grace & Co Conn, The Medical College of Pennsylvania, Vanessa L Appleby, Jill H Krafte, Steven T Trinker, March 2, 1993: US05190918 (20 worldwide citation)

Compounds and compositions comprising fragments and synthetic analogs of human thrombospondin are provided together with methods for their use as thrombospondin-like agents.

2
Jacob Eyal, George Tuszynski: Use of thrombospondin to promote wound healing. W R Grace & Co Conn, Medical College of Pennsylvania, Vanessa L Appleby, Jill H Krafte, Steven T Trinker, October 13, 1992: US05155038 (11 worldwide citation)

Pharmaceutical compositions and dressings useful in wound healing are provided. The pharmaceutical compositions comprise thrombospondin as the active ingredient.

3
Taffy Williams, George Tuszynski, Paul Actor: Retroinverso polypeptides that mimic or inhibit thrombospondin activity. Inkine Pharmaceutical Company, Finnegan Henderson Farabow Garrett & Dunner L, January 15, 2002: US06339062 (6 worldwide citation)

The present invention relates generally to polypeptides that mimic or inhibit the biological activity of thrombospondin, and particularly to polypeptides in retroinverso form. These polypeptides may be used for their biological and pharmaceutical applications such as: (a) inhibiting the invasive and ...

4
Taffy Williams, George Tuszynski, Paul Actor: Compositions for treating chemotherapy-resistant tumor cells and targeted chemotherapy compositions. Inkine Pharmaceutical Company, Philadelphia Health and Education Corporation, Finnegan Henderson Farabow Garrett & Dunner L, April 30, 2002: US06380161 (3 worldwide citation)

The present invention provides methods and compositions for treating cancer and chemotherapy-resistant cancers comprising a chemotherapeutic agent conjugated to or coadministered with a peptide.

5
George Tuszynski, Taffy Williams: Angiocidin: a Cys-Ser-Val-Thr-Cys-Gly specific tumor cell adhesion receptor. Philadelphia Health and Education Corporation, Finnegan Henderson Farabow Garrett & Dunner, September 25, 2003: US20030180295-A1

The present invention provides the sequence of a cell matrix receptor specific for the Cys-Ser-Val-Thr-Cys-Gly (SEQ ID NO: 1) region of thrombospondin. Also provided are purification, cloning and expression methods. The receptor protein is useful in numerous diagnostic, prophylactic and therapeutic ...

6
Taffy Williams, George Tuszynski, Paul Actor: Retroinverso polypeptides that mimic or inhibit thrombospondin. Inkine Pharmaceuticals Mcp Hahnemann, Finnegan Henderson Farabow Garrett & Dunner, September 11, 2003: US20030171298-A1

The present invention relates generally to polypeptides that mimic or inhibit the biological activity of thrombospondin, and particularly to polypeptides in retroinverso form. The peptides. These polypeptides may be used biological and pharmaceutical applications such as: (a) inhibiting the invasive ...


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