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Christopher Hulme, George C Morton, Joseph M Salvino, Richard F Labaudiniere, Helen J Mason, Matthew M Morrissette, Liang Ma, Marie Pierre Cherrier: Methods for preparing N-[(aliphatic or aromatic)carbonyl)]-2-aminoaetamide compounds and for cyclizing such compounds. Aventis Pharamaceuticals, George G Wang, Irving Newman, December 10, 2002: US06492553 (11 worldwide citation)

A method for preparing a N-[(aliphatic or aromatic)carbonyl)]-2-aminoacetamide compound, and for preparing a cyclized compound therefrom, as well as novel resin bound intermediate compounds that are useful for preparing such compounds.


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Timothy F Herpin, George C Morton, Robert P Rehfuss, R Michael Lawrence, Michael A Poss, Jacques Y Roberge, Timur Gungor: receptor inhibitors, Amino-benzazoles as P2Y. Bristol Myers Squibb Company, Jing G Sun, Rosemary M Miano, December 30, 2008: US07470712 (7 worldwide citation)

The present invention provides novel amino-benzazoles and analogues thereof, which are selective inhibitors of the human P2Y1 receptor. The invention also provides for various pharmaceutical compositions of the same and methods for treating diseases responsive to modulation of P2Y1 receptor activity ...


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Gregory S Bisacchi, George C Morton: Benzene acetamide compounds useful as serine protease inhibitors. Bristol Myers Squibb Co, Jing G Sun, Anastasia P Winstow, December 5, 2006: US07144895 (5 worldwide citation)

Compounds having the formula (I), and pharmaceutically-acceptable salts, hydrates, or prodrugs thereof, are useful as serine protease inhibitors, wherein X is —OH, —O(alkyl), —O(aryl), —O(arylalkyl), —NR5(aryl), or —NR5(arylalkyl); W is hydrogen or —(CR7R8)q—W1; W1 is hydrogen or a bond with R6; Z i ...


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Peter W Glunz, Gregory S Bisacchi, George C Morton, Alexandra A Holubec, E Scott Priestley, Xiaojun Zhang, Uwe D Treuner: Phenylglycine derivatives useful as serine protease inhibitors. Bristol Myers Squibb Company, Jing G Sun, October 17, 2006: US07122559 (4 worldwide citation)

Compounds having the formula (I), or a stereoisomer or pharmaceutically-acceptable salt, or hydrate thereof, are useful as factor VIIa inhibitors, wherein X is —NR6S(O)pR16; W is hydrogen or —(CR7R8)q—W1; W1 is hydrogen or a bond with R6; Z is a 5-membered heteroaryl group, a five to six membered he ...


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Guixue Yu, John Macor, Timothy Herpin, R Michael Lawrence, George C Morton, Rejean Ruel, Graham S Poindexter, Edward H Ruediger, Carl Thibault: Compounds useful as modulators of melanocortin receptors and pharmaceutical compositions comprising same. Bristol Myers Squibb Company, Burton Rodney, December 27, 2005: US06979691 (3 worldwide citation)

Compounds having the formula (I), and pharmaceutically-acceptable salts, hydrates and prodrugs thereof, in which E is X is N or CH, W is —NR16R17, —NR16C(═O)R22, —NR16CO2R22, —OR23, or a heteroaryl or heterocyclo group as defined in the specification, and R1 through R12, R16, R17, R22, R23, x, y, an ...


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Guixue Yu, John Macor, Timothy Herpin, R Michael Lawrence, George C Morton, Rejean Ruel, Graham S Poindexter, Edward H Ruediger, Carl Thibault: Compounds useful as modulators of Melanocortin Receptors and pharmaceutical compositions comprising same. Bristol Myers Squibb Co, Laurelee A Duncan, June 27, 2006: US07067525 (3 worldwide citation)

Compounds having the formula (I), G is a novel side chain selected from C2-6alkenyl, A3-aryl, —OR18, heteroaryl, A1-cyano, A2—OR17, A1—C(═O)R18, A1—CO2R18, A1—C(═O)NR18R19, A1—OC(═O)R18, A1—NR18C(═O)R19, A1—OC(═O)NR18R19, A1—NR18CO2R19, A1—NR18SO2R17, A1—SO2R17, A1—NR20C(═O)NR18R19, and A1—SR18; or ...


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Joseph M Salvino, George C Morton, Helen J Mason, Richard F Labaudiniere: Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and &agr;&bgr;-unsaturated carboxylic acid and aldehyde compounds. Aventis Pharmaceuticals, George G Wang, Irving Newman, May 21, 2002: US06392010 (3 worldwide citation)

This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and &agr;,&bgr;-unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.


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Timothy F Herpin, George C Morton, Robert P Rehfuss, R Michael Lawrence, Michael A Poss, Jacques Y Roberge, Timur Gungor: receptor inhibitors with pyridine ring and heterocyclic components, Amino-benzazoles as P2Y. Bristol Myers Squibb Company, Jing G Sun, November 8, 2011: US08053450 (2 worldwide citation)

The present invention provides novel amino-benzazoles and analogues thereof, which are selective inhibitors of the human P2Y1 receptor. The invention also provides for various pharmaceutical compositions of the same and methods for treating diseases responsive to modulation of P2Y1 receptor activity ...


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Joseph M Salvino, George C Morton, Helen J Mason, Richard F Labaudiniere: Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and .alpha..beta.-unsaturated carboxylic acid and aldehyde compounds. Aventis Pharmaceuticals Products, Ross J Oehler, October 17, 2000: US06133409 (2 worldwide citation)

This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and .alpha.,.beta.-unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.