1
Francis Barany, George Barany, Robert P Hammer, Maria Kempe, Herman Blok, Monib Zirvi: Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays. Cornell Research Foundation, Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, Regents of the University of Minnesota, Nixon Peabody, February 8, 2005: US06852487 (181 worldwide citation)

The present invention describes a method for identifying one or more of a plurality of sequences differing by one or more single base changes, insertions, deletions, or translocations in a plurality of target nucleotide sequences. The method includes a ligation phase, a capture phase, and a detectio ...


2
Francis Barany, Norman P Gerry, Nancy E Witowski, Joseph Day, Robert P Hammer, George Barany: Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays. Nixon Peabody, January 14, 2003: US06506594 (100 worldwide citation)

The present invention describes a method for identifying one or more of a plurality of sequences differing by one or more single base changes, insertions, deletions, or translocations in a plurality of target nucleotide sequences. The ligation phase utilizes a ligation detection reaction between one ...


3
Francis Barany, Matthew Lubin, George Barany, Robert P Hammer: Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions. Cornell Research Foundation, Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, Regents of the University of Minnesota, Nixon Peabody, September 28, 2004: US06797470 (70 worldwide citation)

The present invention relates to the detection of nucleic acid sequence differences using coupled ligase detection reaction and polymerase chain reaction. One aspect of the present invention involves use of a ligase detection reaction coupled to a polymerase chain reaction. Another aspect of the pre ...


4
Maria Kempe, George Barany: Highly cross-linked polymeric supports. Regents Of The University Of Minnesota, Mueting Raasch & Gebhardt P A, June 8, 1999: US05910554 (62 worldwide citation)

A polymer useful as a solid support for a variety of applications is provided. The polymer is prepared from a composition comprising at least one type of olefinic monomer and a multifunctional (meth)acrylate crosslinker of the following formula (I): ##STR1## wherein: (a) R.sup.1, R.sup.2, and R.sup. ...


5
Francis Barany, Matthew Lubin, George Barany, Robert P Hammer: Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions. Cornell Research Foundation, Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, Regents of the University of Minnesota, Nixon Peabody, April 29, 2008: US07364858 (42 worldwide citation)

The present invention relates to a method for identifying a target nucleotide sequence. This method involves forming a ligation product on a target nucleotide sequence in a ligase detection reaction mixture, amplifying the ligation product to form an amplified ligation product in a polymerase chain ...


6
Francis Barany, George Barany, Robert P Hammer, Maria Kempe, Herman Blok, Monib Zirvi: Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays. Cornell Research Foundation, Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, Regents of the University of Minnesota, Nixon Peabody, August 1, 2006: US07083917 (42 worldwide citation)

The present invention describes a method for identifying one or more of a plurality of sequences differing by one or more single base changes, insertions, deletions, or translocations in a plurality of target nucleotide sequences. The method includes a ligation phase, a capture phase, and a detectio ...


7
Francis Barany, Matthew Lubin, George Barany, Robert P Hammer, Phillip Belgrader: Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions. Cornell Research Foundation, Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, Regents of the University of Minnesota, Nixon Peabody, August 29, 2006: US07097980 (41 worldwide citation)

The present invention relates to the detection of nucleic acid sequence differences using coupled ligase detection reaction and polymerase chain reaction. One aspect of the present invention involves use of a ligase detection reaction coupled to a polymerase chain reaction. Another aspect of the pre ...


8
Francis Barany, Matthew Lubin, George Barany, Robert P Hammer: Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions. Cornell Research Foundation, Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, Regents of the University of Minnesota, Nixon Peabody, January 23, 2007: US07166434 (37 worldwide citation)

The present invention relates to the detection of nucleic acid sequence differences using coupled ligase detection reaction and polymerase chain reaction. One aspect of the present invention involves use of a ligase detection reaction coupled to a polymerase chain reaction. Another aspect of the pre ...


9
Francis Barany, Matthew Lubin, George Barany, Robert P Hammer: Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions. Cornell Research Foundation, Regents of the University of Minnesota, Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, Nixon Peabody, December 25, 2007: US07312039 (33 worldwide citation)

The present invention relates to a method for identifying a target nucleotide sequence. This method involves forming a ligation product on a target nucleotide sequence in a ligase detection reaction mixture, amplifying the ligation product to form an amplified ligation product in a polymerase chain ...


10
George Barany, Fernando Albericio, Jane Chang, Samuel Zalipsky, Nuria A Sole: Polyethylene glycol derivatives for solid-phase applications. University of Minnesota, Hamilton Brook Smith & Reynolds, August 10, 1993: US05235028 (33 worldwide citation)

The present invention pertains to polyethylene glycol (PEG) derivatized graft supports, to methods for making these supports and to methods of using the supports to synthesize peptides by solid-phase synthesis techniques. The PEG-graft supports of this invention comprise functionalized PEG derivativ ...