1
Paul A Levine, Jason A Sholder, Gene A Bornzin, Joseph J Florio, Kenneth Valikai, Lisa P Weinberg: Implantable stimulation device having means for operating in a preemptive pacing mode to prevent tachyarrhythmias and method thereof. Pacesetter, May 2, 2000: US06058328 (390 worldwide citation)

Preemptive tachyarrhythmia pacing is provided in an implantable cardiac-stimulation device, such as an implantable pacemaker or defibrillator, by modifying the operation of the implantable device in a way that minimizes the likelihood of occurrence of a tachyarrhythmia. The behavior modification is ...


2
Gene A Bornzin, Elia R Arambula, Joseph J Florio: System and method for modulating the base rate during sleep for a rate-responsive cardiac pacemaker. Pacesetter, Lisa P Weinberg, December 19, 1995: US05476483 (323 worldwide citation)

A system and method are provided for modulating the base rate of a transfer function for a rate-responsive cardiac pacemaker. Activity sensor measurements are used to derive activity variance measurements, which in turn are used to modulate the base pacing rate. In one embodiment, a histogram is use ...


3
Euljoon Park, Gene A Bornzin, Joseph J Florio, Kerry Bradley, William Gibb: Implantable cardiac stimulation device and method for varying pacing parameters to mimic circadian cycles. Pacesetter, October 3, 2000: US06128534 (246 worldwide citation)

Provided herein are methods and apparatus for automatically adjusting pacing parameters in implantable programmable stimulation devices, such as rate-responsive pacemakers and cardioverter defibrillators. The methods and apparatus provide a circadian varying pacing parameter (e.g., pacing rate, AV D ...


4
Euljoon Park, Steve Koh, Gene A Bornzin: Stimulation device for sleep apnea prevention, detection and treatment. Pacesetter, August 9, 2005: US06928324 (240 worldwide citation)

An implantable cardiac stimulation device comprises a metabolic demand sensor, an activity sensor, and one or more pulse generators. The metabolic demand sensor and activity sensor can sense metabolic demand and physical activity parameters, respectively. The pulse generators can generate cardiac pa ...


5
Anne M Pianca, Gene A Bornzin, Euljoon Park, Joseph J Florio, Alan B Vogel, Lee Jay Mandell, Junyu Mai: AC/DC multi-axis accelerometer for determining patient activity and body position. Pacesetter, October 15, 2002: US06466821 (216 worldwide citation)

An implantable cardiac stimulation device which determines stimulation based upon the patient's body position and activity level while eliminating special implantation or calibration procedures. To eliminate such special implantation and calibration procedures, the stimulation device correlates ...


6
Mark W Kroll, Chris Sorensen, Gene A Bornzin: Detection of patient's position and activity status using 3D accelerometer-based position sensor. Pacesetter, December 2, 2003: US06658292 (188 worldwide citation)

An implantable cardiac stimulation device is equipped with an accelerometer-based sensor to sense a patient's movement and produce a vertical acceleration component indicative of a patient's acceleration in a vertical direction. A vertical velocity component is computed from the vertical a ...


7
Gene A Bornzin, Kelly H McClure, Gabriel Mouchawar, Sheldon B Moberg: System and method for providing hemodynamically optimal pacing therapy. Pacesetter, Lisa P Weinberg, August 27, 1996: US05549650 (181 worldwide citation)

A system and method for a pacemaker are provided, for using cardiac wall motion sensor signals to provide hemodynamically optimal pacing therapy to patient at rest, and for providing rate-responsive pacing therapy. The cardiac wall motion sensor signals are provided by an implantable lead that incor ...


8
Mark W Kroll, Gene A Bornzin: Stimulation of autonomic nerves. Pacesetter, October 17, 2006: US07123961 (178 worldwide citation)

An exemplary method for stimulating an autonomic nerve that includes delivering power to, for example, an electrode at a set power level, determining whether the delivering achieved an autonomic response that affected cardiac function, and delivering power to the electrode at a reduced power level i ...


9
Gene A Bornzin: Implantable stimulation device having means for optimizing current drain. Pacesetter, December 16, 1997: US05697956 (163 worldwide citation)

An implantable pacemaker maintains a prescribed relationship between stimulation pulse amplitude and pulse width so as to provide an adequate safety factor above a stimulation threshold, while minimizing the current drain on the pacemaker battery. A series of stimulation pulse energies, each realize ...


10
Gene A Bornzin, Elia R Arambula, Joseph J Florio: System and method for automatically determining the slope of a transfer function for a rate-responsive cardiac pacemaker. Pacesetter, Lisa P Weinberg, May 7, 1996: US05514162 (147 worldwide citation)

A rate-responsive pacemaker measures a patient's level of activity and stores the results in an activity level histogram. The patient's average level of activity is maintained as a running average. Based on a prescribed base pacing rate, a prescribed maximum pacing rate, the average level of activit ...