1
Mark A Gallop, Ge Peng, Thomas F Woiwode, Kenneth C Cundy: Gemcitabine prodrugs, pharmaceutical compositions and uses thereof. XenoPort, Dorsey & Whitney, September 4, 2007: US07265096 (36 worldwide citation)

The present invention provides gemcitabine prodrugs, methods of making gemcitabine prodrugs, pharmaceutical compositions of gemcitabine prodrugs and methods of using gemcitabine prodrugs and pharmaceutical compositions thereof to treat or prevent diseases or disorders such as cancer or viral infecti ...


2
Mark A Gallop, Xuedong Dai, Randall A Scheuerman, Stephen P Raillard, Suresh K Manthati, Fenmei Yao, Thu Phan, Maria Ludwikow, Ge Peng, Seema Bhat: Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof. XenoPort, Dorsey & Whitney, June 5, 2007: US07227028 (34 worldwide citation)

Methods for synthesis of 1-(acyloxy)-alkyl carbamates, particularly, the synthesis of 1-(acyloxy)-alkyl carbamate prodrugs of primary or secondary amine-containing drugs are described. Also described are methods for synthesis of 1-(acyloxy)-alkyl N-hydroxysuccinimidyl carbonates which are useful int ...


3
Mark A Gallop, Fenmei Yao, Maria J Ludwikow, Thu Phan, Ge Peng: Acyloxyalkyl carbamate prodrugs, methods of synthesis and use. XenoPort, Richard F Trecartin Esq, Dorsey & Whitney, September 19, 2006: US07109239 (19 worldwide citation)

The disclosures herein relate generally to acyloxyalkyl carbamate prodrugs of (±)-4-amino-3-(4-chlorophenyl)butanoic acid and analogs thereof, pharmaceutical compositions thereof, methods of making prodrugs of (±)-4-amino-3-(4-chlorophenyl)butanoic acid and analogs thereof, methods of using prodrugs ...


4
Mark A Gallop, Feng Xu, Thu Phan, Usha Dilip, Ge Peng: Acyloxyalkyl carbamate prodrugs, methods of synthesis and use. XenoPort, D Byron Miller, William R Lambert, Lucy S Chang, July 6, 2010: US07749985 (17 worldwide citation)

Acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphinic acid and analogs thereof, methods of making acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphinic acid and analogs thereof, methods of using acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphinic acid and analogs thereof, and pharma ...


5
Feng Xu, Mark A Gallop, Ge Peng, Thu Phan, Usha Dilip, David J Wustrow: receptor ligands, Gamma-amino-butyric acid derivatives as GABA. XenoPort, Kilpatrick Townsend & Stockton, January 1, 2013: US08344028 (15 worldwide citation)

Gamma-amino-butyric acid derivatives that are GABAB receptor ligands, pharmaceutical compositions comprising such derivatives, and methods of using such derivatives and pharmaceutical compositions thereof for treating diseases are disclosed.


6
Mark A Gallop, Xuedong Dai, Randall A Scheuerman, Stephen P Raillard, Suresh K Manthati, Fenmei Yao, Thu Phan, Maria Ludwikow, Ge Peng, Seema Bhat: Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof. XenoPort, Dorsey & Whitney, March 31, 2009: US07511158 (12 worldwide citation)

Methods for synthesis of 1-(acyloxy)-alkyl carbamates, particularly, the synthesis of 1-(acyloxy)-alkyl carbamate prodrugs of primary or secondary amine-containing drugs are described. Also described are methods for synthesis of 1-(acyloxy)-alkyl N-hydroxysuccinimidyl carbonates which are useful int ...


7
Mark A Gallop, Fenmei Yao, Maria J Ludwikow, Thu Phan, Ge Peng: Acyloxyalkyl carbamate prodrugs, methods of synthesis and use. Xenoport, Dorsey & Whitney, November 27, 2007: US07300956 (9 worldwide citation)

The disclosures herein relate generally to acyloxyalkyl carbamate prodrugs of (±)-4-amino-3-(4-chlorophenyl)butanoic acid and analogs thereof, pharmaceutical compositions thereof, methods of making prodrugs of (±)-4-amino-3-(4-chlorophenyl)butanoic acid and analogs thereof, methods of using prodrugs ...


8
Mark A Gallop, Ge Peng, Thomas F Woiwode, Kenneth C Cundy: Gemcitabine prodrugs, pharmaceutical compositions and uses thereof. XenoPort, Dorsey & Whitney, October 27, 2009: US07608602 (4 worldwide citation)

The present invention provides gemcitabine prodrugs, methods of making gemcitabine prodrugs, pharmaceutical compositions of gemcitabine prodrugs and methods of using gemcitabine prodrugs and pharmaceutical compositions of using gemcitabine prodrugs to treat or prevent diseases or disorders such as c ...


9
Ge Peng, Zhong Leiming: Ruggedized forensic light source. Horiba Jobin Yvon, Kirkpatrick & Lockhart, Anthony H Handal, March 1, 2005: US06862093 (4 worldwide citation)

A forensic light source uses a pair of filter wheels to achieve a combination of the characteristics of filters on different wheels and may include a housing which supports the light, filter wheels and other parts with shock absorbing members such as rubber washers or the like to achieve a shock res ...


10
Mark A Gallop, Ge Peng, Thomas F Woiwode, Kenneth C Cundy: Gemcitabine prodrugs, pharmaceutical compositions and uses thereof. XenoPort, Dorsey & Whitney, September 28, 2010: US07803785 (3 worldwide citation)

The present invention provides gemcitabine prodrugs, methods of making gemcitabine prodrugs, pharmaceutical compositions of gemcitabine prodrugs and methods of using gemcitabine prodrugs and pharmaceutical compositions of using gemcitabine prodrugs to treat or prevent diseases or disorders such as c ...