1
David D Davey, Gary B Phillips: Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants. Berlex Laboratories, Carol J Roth, October 3, 2000: US06127376 (75 worldwide citation)

This invention is directed to aryl and heterocyclyl substituted pyrimidine derivatives selected from the following formulae: ##STR1## wherein Z.sup.1, Z.sup.2, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are defined herein. These compounds are useful as anti-coagulants.


2
Damian O Arnaiz, Yuo Ling Chou, Brian D Griedel, Rushad E Karanjawala, Monica J Kochanny, Wheeseong Lee, Amy Mei Liang, Michael M Morrissey, Gary B Phillips, Karna Lyn Sacchi, Steven T Sakata, Kenneth J Shaw, R Michael Snider, Shung C Wu, Bin Ye, Zuchun Zhao: Ortho-anthranilamide derivatives as anti-coagulants. Berlex Laboratories, Carol J Roth, October 31, 2000: US06140351 (61 worldwide citation)

This invention is directed to compounds of formula (III): ##STR1## wherein B, C, D, E, R.sup.1, R.sup.2 and R.sup.3 are disclosed herein. These compounds are disclosed as being useful as anti-coagulants.


3
Brad O Buckman, David D Davey, William J Guilford, Michael M Morrissey, Howard P Ng, Gary B Phillips, Shung C Wu, Wei Xu: Benzamidine derivatives and their use as anti-coagulants. Berlex Laboratories, Carol J Roth, November 25, 1997: US05691364 (61 worldwide citation)

This invention is directed to benzamidine derivatives which are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the invention, and methods of using the compounds to treat disease-states characterized by thrombotic activity.


4
David D Davey, Gary B Phillips: Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants. Berlex Laboratories, Carol J Roth, April 16, 2002: US06372751 (47 worldwide citation)

This invention is directed to aryl and heterocyclyl substituted pyrimidine derivatives selected from the following formulae:


5

6

7
Gary B Phillips: Polyhydroxylated monocyclic N-heterocyclic derivatives as anti-coagulants. Berlex Laboratories, Carol J Roth, July 17, 2001: US06262088 (33 worldwide citation)

This invention is directed to poly-hydroxylated monocyclic N-heterocyclic derivatives selected from the following formulae:


8
Brad O Buckman, David D Davey, William J Guilford, Michael M Morrissey, Howard P Ng, Gary B Phillips, Shung C Wu, Wei Xu: Benzamidine derivatives and their use as anti-coagulants. Berlex Laboratories, Carol J Roth, October 23, 2001: US06306884 (24 worldwide citation)

This invention is directed to benzamidine derivatives which are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the invention, and methods of using the compounds to treat disease-states characterized by thrombotic activity.


9
Brad O Buckman, David D Davey, William J Guilford, Michael M Morrissey, Howard P Ng, Gary B Phillips, Shung C Wu, Wei Xu: Benzamidine derivatives and their use as anti-coagulants. Berlex Laboratories, Carol J Roth, March 2, 1999: US05877181 (22 worldwide citation)

This invention is directed to benzamidine derivatives which are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the invention, and methods of using the compounds to treat disease-states characterized by thrombotic activity.


10
Brad O Buckman, David D Davey, William J Guilford, Michael M Morrissey, Howard P Ng, Gary B Phillips, Shung C Wu, Wei Xu: Benzamidine derivatives and their use as anti-coagulants. Berlex Laboratories, Carol J Roth, March 16, 1999: US05883100 (21 worldwide citation)

This invention is directed to benzamidine derivatives which are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the invention, and methods of using the compounds to treat disease-states characterized by thrombotic activity.