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Dey Kaka, Gao Donghong Amy, Goldberg Daniel R, Heim Riether Alexander, Mangette John E, Mugge Ingo Andreas, Snow Roger, Swinamer Alan David, Wu Jiang Ping, Xiong Zhaoming, Yang Yu: Ccr10 antagonists. Boehringer Ingelheim International, Boehringer Ingelheim Pharma & Co Kg, Dey Kaka, Gao Donghong Amy, Goldberg Daniel R, Heim Riether Alexander, Mangette John E, Mugge Ingo Andreas, Snow Roger, Swinamer Alan David, Wu Jiang Ping, Xiong Zhaoming, Yang Yu, MORRIS Michael P, April 23, 2009: WO/2009/052078 (21 worldwide citation)

The invention relates to a compound of formula (I) or a tautomer thereof or a pharmaceutically acceptable salt thereof, wherein R1 to R11, W, X, Y, Z, and n are as defined herein. The invention also relates to methods of using the compounds of formula (I) and compositions thereof to treat various di ...


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Gao Donghong Amy, Goldberg Daniel R, Hammach Abdelhakim, Hao Ming Hong, Moss Neil, Qian Kevin Chungeng, Roth Gregory Paul, Sarko Christopher Ronald, Swinamer Alan David, Xiong Zhaoming, Kamhi Victor Marc: Derives damides heterocycliques utilises en tant quinhibiteurs de cytokine, Heterocyclic amide derivatives as cytokine inhibitors. Boehringer Ingelheim Pharmaceuticals, Boehringer Ingelheim Pharmaceuticals, Fetherstonhaugh & Co, June 14, 2011: CA2478232

Disclosed are amide compounds of formula (I) wherein Ar1, Q, Y and R3-R6 of formula (I) are defined herein. The compounds inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic in ...


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GAO DONGHONG AMY, MOSS NEIL, WANG JI, WU JIANG PING, WU LIFEN, XIONG ZHAOMING: 2-ARYLCARBAMOYLINDOLES EN TANT QUINHIBITEURS DE LA CYTOKINE, 2-ARYLCARBAMOYL-INDOLES AS CYTOKINE INHIBITORS. BOEHRINGER INGELHEIM PHARMACEUTICALS, BOEHRINGER INGELHEIM PHARMACEUTICALS, FETHERSTONHAUGH & CO, June 25, 2013: CA2577446

Disclosed are compounds of formula (I) which inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compound ...


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Gao Donghong Amy, Goldberg Daniel R, Hammach Abdelhakim, Hao Ming Hong, Moss Neil, Qian Kevin Chungeng, Roth Gregory Paul, Sarko Christopher Ronald, Swinamer Alan David, Xiong Zhaoming, Kamhi Victor Marc: Heterocyclic amide derivatives as cytokine inhibitors. Boehringer Ingelheim Pharmaceuticals, RAYMOND Robert P, October 23, 2003: WO/2003/087085

Disclosed are amide compounds of formula (I) wherein Ar1, Q, Y and R3-R6 of formula (I) are defined herein. The compounds inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic in ...


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Gao Donghong Amy, Moss Neil, Wang Ji, Wu Jiang Ping, Wu Lifen, Xiong Zhaoming: Cytokine inhibitors. Boehringer Ingelheim Pharmaceuticals, Gao Donghong Amy, Moss Neil, Wang Ji, Wu Jiang Ping, Wu Lifen, Xiong Zhaoming, MORRIS Michael P, March 9, 2006: WO/2006/026235

Disclosed are compounds of formula (I) which inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compound ...


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Cirillo Pier Francesco, Gao Donghong Amy, Goldberg Daniel R, Hammach Abdelhakim, Hao Ming Hong, Kamhi Victor Marc, Moss Neil, Netherton Russell, Qian Kevin Chungeng, Ralph Mark Stephen, Wu Lifen, Xiong Zhaoming, Aungst Ronald A Jr: Heterocyclic n-aryl carboxamides as cytokine inhibitors. Boehringer Ingelheim Pharma, zhangbeng yuan, August 13, 2008: CN200810083505

Disclosed are compounds of formula (I) where Ar1, X, Y, Q, W, R, R, R, R and R are defined herein. The compounds of the invention inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as ch ...


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Cirillo Pier Francesco, Gao Donghong Amy, Goldberg Daniel R, Hammach Abdelhakim, Hao Ming Hong, Kamhi Victor Marc, Moss Neil, Netherton Russell, Qian Kevin Chungeng, Ralph Mark Stephen, Wu Lifen, Xiong Zhaoming, Aungst Ronald A Jr: Heterocyclic n-aryl carboxamides as cytokine inhibitors. Boehringer Ingelheim Pharmaceuticals, November 15, 2005: KR1020057016939

Disclosed are compounds of formula (I) where Ar1, X, Y, Q, W, R3, R4, R5, R6 and Ry are defined herein. The compounds of the invention inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such ...