1
Shubhayu Basu, Gene Michal, Florian Ludwig, Jinping Wan, John Stankus: Cytocompatible alginate gels. Abbott Cardiovascular Systems, Squire Sanders, Randy Shen Esq, October 23, 2012: US08293226 (8 worldwide citation)

The present invention relates to a method of making cytocompatible alginate gels and their use in the treatment of cardiomyopathy.


2
Shubhayu Basu, Gene Michal, Florian Ludwig, Jinping Wan, John Stankus: Cytocompatible alginate gels. Abbott Cardiovascular Systems, Squire Sanders, Randy Shen Esq, July 17, 2012: US08221744 (7 worldwide citation)

The present invention relates to a method of making cytocompatible alginate gels and their use in the treatment of cardiomyopathy.


3
Shubhayu Basu, Gene Michal, Florian Ludwig, Jinping Wan, John Stankus: Cytocompatible alginate gels. Abbott Cardiovascular Systems, Squire Sanders, Randy Shen Esq, March 5, 2013: US08388948 (6 worldwide citation)

The present invention relates to a method of making cytocompatible alginate gels and their use in the treatment of cardiomyopathy.


4
Pamela A Kramer Brown, Florian Ludwig: Implantable medical devices for local and regional treatment. Abbott Cardiovascular Systems, Squire Sanders, August 28, 2012: US08252361 (5 worldwide citation)

Implantable medical devices adapted to erodibly release delivery media for local and regional treatment are disclosed.


5
Syed F A Hossainy, Jinping Wan, Dariush Davalian, Florian Ludwig, Katsuyuki Murase: Sustained release of apo A-I mimetic peptides and methods of treatment. Abbott Cardiovascular Systems, Randy Shen, Blakely Sokoloff Taylor & Zafman, October 25, 2011: US08044021 (3 worldwide citation)

A method including advancing a delivery device through a lumen of a blood vessel to a particular region in the blood vessel; and introducing a composition including a sustained-release carrier and an apolipoprotein A-I (apo A-I) synthetic mimetic peptide into a wall of the blood vessel at the partic ...


6
Katsuyuki Murase, Florian Ludwig, Dariush Davalian: Bioactive agent-loaded heart-targeting nanoparticles. Abbott Cardiovascular Systems, Squire Sanders, April 29, 2014: US08709472 (3 worldwide citation)

Compositions that contain bioactive agent-loaded nanoparticles with heart targeting capabilities and methods of using the same for the treatment of disease are disclosed.


7
Shubhayu Basu, Randolf von Oepen, Eugene Michal, Florian Ludwig: Methods of modifying myocardial infarction expansion. Abbott Cardiovascular Systems, Blakely Sokoloff Taylor & Zafman, February 19, 2013: US08377033 (2 worldwide citation)

A reinforcement region is formed within the myocardium by introducing a delivery device through a vessel wall to a treatment site within a myocardium. A biomaterial is then delivered to the treatment site as the delivery device is withdrawn from the treatment site to form the reinforcement regions. ...


8
Yunbing Wang, David C Gale, Bin Huang, Mikael O Trollsas, Thierry Glauser, Florian Ludwig: Implantable medical devices fabricated from branched polymers. Abbott Cardiovascular Systems, Squire Sanders, July 16, 2013: US08486135 (1 worldwide citation)

This invention relates to implantable medical devices, such as stents, fabricated from hyperbranched-like polymers, comb-like polymers, star polymers, dendrimer-like star polymers, dendrimers, and mixtures thereof.


9
Klaus Kleine, David C Gale, Fozan El Nounou, Syed F A Hossainy, Florian Ludwig: Drug delivery spiral coil construct. Advanced Cardiovascular Systems, Squire Patton Boggs, February 7, 2017: US09561351

An implantable medical device is disclosed having a helical construct including a set of spiral coils for local in vivo application of a therapeutic substance in a biological lumen. The helical construct is configured to apply less than 0.75 Bar of pressure to the biological lumen wall. The helical ...


10
Paul M Consigny, David C Gale, Florian Ludwig, Randolpf von Oepen, Fozan O El Nounou, Pamela A Kramer Brown, Travis R Yribarren, William E Webler Jr: Method and apparatus for delivering an agent to a kidney. Abbott Cardiovascular Systems, Randy Shen Esq, Blakely Sokoloff Taylor & Zafman, September 29, 2015: US09144509

Devices for delivering drugs or other treatment agents locally to the vasculature of a mammal are disclosed. These devices have several related structures and are designed to deliver the drugs to facilitate rapid mixing with the blood flowing past the devices.