1
Morrison Christopher, Robson Barry, Fishleigh Robert: Improvements in or relating to hormones.. Proteus Molecular Design, December 7, 1988: EP0293530-A2 (4 worldwide citation)

An analogue of lutenising hormone-releasing hormone (LHRH) having the amino acid sequence: pGlg-His-Trp-Ser-Tyr-X-Len-Arg-Pro-Gly-Y-Z wherein X represents Gly or a D-amino acid, Y represents one or more amino acid residues, which may be the same of different, and Z represents Cys or Tyr, such that t ...


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Fishleigh Robert V, Robson Barry: Synthetic polypeptides.. Proteus Biotech, January 11, 1989: EP0298633-A2 (2 worldwide citation)

The invention relates to novel polypeptides. It particularly relates to polypeptides with a three-dimensional structure analogous to the three-dimensional structure of specific sites on the exterior surface of viral envelope proteins. It is of particular interest to the design of vaccines, diagnosti ...


4
Fishleigh Robert Vincent, Robson Barry: Analogs of piscine lhrh. Proteus Molecular Design, December 8, 1993: GB2267496-A

An analog of piscine GnRH is disclosed having the amino acid sequence: pGlu-His-Trp-Ser-Tyr-W-Trp-Leu-Arg-Pro-Gly-X-Y-Z wherein W represents Gly or a D-amino acid, X represents a bond, or one or more amino acids which may be the same or different, Y represents Cys or Tyr or is absent, and Z is absen ...


5
Fishleigh Robert V, Robson Barry, Mee Roger P: Peptides en rapport avec des proteines de type prion, Peptides related to prion proteins. Proteus Molecular Design, Proteus Molecular Design, FETHERSTONHAUGH & CO, June 10, 1993: CA2124953

Synthetic polypeptides having at least one antigenic site of a prion protein are disclosed together with methods for their use and manufacture and antibodies raised against such polypeptides. Diagnostic kits using the polypeptides and/or antibodies are also disclosed.


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Robson Barry, Morrison Christopher A, Fishleigh Robert V: Analogues de lhrh permettant une augmentation de lanitgentcite par conjugaison, Analogues of lhrh allowing increased antigenicity through conjugation. Proteus Biotechnology, Proteus Molecular Design, FETHERSTONHAUGH & CO, June 27, 2000: CA1341039

An analogue of lutenising hormone-releasinghormone (LHRH) having the amino acid sequence:pGlg-His-Trp-Ser-Tyr-X-Leu-Arg-Pro-Gly-Y-Zwherein X represents Gly or a D-amino acid, Y represents one or more amino acid residues, whichmay be the same or different, and Z represents Cys or Tyr, such that the s ...


7
Fishleigh Robert Vincent, Robson Barry, Aston Roger: Synthetic polypeptides derived from the hiv envelope glycoprotein. Proteus Molecular Design, Fishleigh Robert Vincent, Robson Barry, Aston Roger, HILDYARD Edward Martin, October 28, 1993: WO/1993/021218

A synthetic polypeptide has at least one antigenic property of the envelope protein of at least one strain of Human Immunodeficiency Virus (HIV), said polypeptide consists substantially of an amino acid sequence of the formula (I): X-R¿1?-Leu-R¿2?-Leu-Thr-Val-Trp-Gly-R¿3?-Lys-Y, wherein R¿1? is sele ...


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Fishleigh Robert Vincent, Robson Barry: Synthetic polypeptides. Proteus Molecular Design, Fishleigh Robert Vincent, Robson Barry, FRANK B DEHN Imperial House 15 19 Kingsway London WC2B 6UZ, September 19, 1991: WO/1991/013909

The synthetic polypeptides disclosed comprise at least one antigenic property of the envelope protein of at least one strain of Human Immunodeficiency Virus (HIV). A preferred sequence is X-Asp-Gln-Ser-Leu-Lys-Gly-Ile-Trp-Gly-Cys-Ser-Gly-Lys-Leu-Ala-Cys-Y wherein X and Y may each independently be ab ...


9
Fishleigh Robert Vincent, Robson Barry: Analogs of piscine lhrh. Proteus Molecular Design, Fishleigh Robert Vincent, Robson Barry, FRANK B DEHN Imperial House 15 19 Kingsway London WC2B 6UZ, July 23, 1992: WO/1992/012247

An analog of piscine GnRH is disclosed having the amino acid sequence: pGlu-His-Trp-Ser-Tyr-W-Trp-Leu-Arg-Pro-Gly-X-Y-Z wherein W represents Gly or a D-amino acid, X represents a bond, or one or more amino acids which may be the same or different, Y represents Cys or Tyr or is absent, and Z is absen ...


10
Fishleigh Robert Vincent, Robson Barry, Greaney Paul John: Polypeptide antigens of mycobacterium bovis. Proteus Molecular Design, Fishleigh Robert Vincent, Robson Barry, Greaney Paul John, HILDYARD Edward Martin, February 3, 1994: WO/1994/002508

The invention provides a synthetic polypeptide having at least one antigenic property of the MPB-70 protein of at least one strain of $i(Mycobacterium bovis), said polypeptide of Formula (I) comprising an amino acid sequence selected from Formulae Seq. ID Nos 1-14: Seq. ID No 1: X-Glu-Tyr-Ala-Ala-Al ...