1
Evan C Unger, David W Yellowhair: Methods and apparatus for performing diagnostic and therapeutic ultrasound simultaneously. ImaRx Pharmaceutical, Woodcock Washburn Kurtz Mackiewicz & Norris, September 24, 1996: US05558092 (406 worldwide citation)

Methods and apparatus for performing diagnostic ultrasound simultaneously with the application of therapeutic ultrasonic waves are disclosed. The methods and apparatus are particularly advantageous in performing ultrasonic imaging of a region of a patient while simultaneously applying therapeutic ul ...


2
Evan C Unger, Thomas A Fritz, Terry Matsunaga, VaradaRajan Ramaswami, David Yellowhair, Guanli Wu: Therapeutic drug delivery systems. ImaRx Pharmaceutical, Woodcock Washburn Kurtz Mackiewicz & Norris, December 3, 1996: US05580575 (298 worldwide citation)

Therapeutic drug delivery systems comprising gas-filled microspheres comprising a therapeutic are described. Methods for employing such microspheres in therapeutic drug delivery applications are also provided. Drug delivery systems comprising gas-filled liposomes having encapsulated therein a drug a ...


3
Evan C Unger: Methods for providing localized therapeutic heat to biological tissues and fluids. Woodcock Washburn Kurtz Mackiewicz & Norris, September 22, 1992: US05149319 (264 worldwide citation)

Gas, gaseous precursors and prefluorocarbons are presented as novel potentiators for ultrasonic hyperthermia. The gas, gaseous precursors and perfluorocarbons which may be administered into the vasculature, interstitially or into any body cavity are designed to accumulate in cancerous and diseased t ...


4
Evan C Unger, Thomas A Fritz, Terry Matsunaga, VaradaRajan Ramaswami, David Yellowhair, Guanli Wu: Therapeutic delivery systems related applications. ImaR sub x Pharmaceutical, Woodcock Washburn Kurtz Mackiewicz & Norris, August 6, 1996: US05542935 (263 worldwide citation)

Therapeutic delivery systems comprising gaseous precursor-filled microspheres comprising a therapeutic are described. Methods for employing such microspheres in therapeutic delivery applications are also provided. Therapeutic delivery systems comprising gaseous precursor-filled liposomes having enca ...


5
Evan C Unger, Terry O Matsunaga, David Yellowhair: Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles. ImaRx Pharmaceutical, Woodcock Washburn Kurtz Mackiewicz & Norris, March 31, 1998: US05733572 (255 worldwide citation)

Gas and gaseous precursor filled microspheres, and foams thereof, provide novel topical and subcutaneous delivery vehicles for various active ingredients, including drugs and cosmetics.


6
Evan C Unger, Thomas A Fritz, Terry Matsunaga, VaradaRajan Ramaswami, David Yellowhair, Guanli Wu: Methods of preparing gas-filled liposomes. ImaR sub x Pharmaceutical, Woodcock Washburn Kurtz Mackiewicz & Norris, November 28, 1995: US05469854 (247 worldwide citation)

Methods of and apparatus for preparing gas-filled liposomes are described. Gas-filled liposomes prepared by these methods are particularly useful, for example, in ultrasonic imaging applications and in therapeutic drug delivery systems.


7
Evan C Unger, Thomas A Fritz, Terry Matsunaga, VaradaRajan Ramaswami, David Yellowhair, Guanli Wu: Method of preparing gas and gaseous precursor-filled microspheres. ImaRx Pharmaceutical, Woodcock Washburn Kurtz Mackiewicz & Norris, December 17, 1996: US05585112 (215 worldwide citation)

Methods of and apparatus for preparing temperature activated gaseous precursor-filled liposomes are described. Gaseous precursor-filled liposomes prepared by these methods are particularly useful, for example, in ultrasonic imaging applications and in therapeutic drug delivery systems.


8
Evan C Unger, Thomas A Fritz, Terry Matsunaga, VaradaRajan Ramaswami, David Yellowhair, Guanli Wu: Therapeutic drug delivery systems. ImaRx Pharmaceutical, Woodcock Washburn Kurtz Mackiewicz & Norris, June 23, 1998: US05770222 (211 worldwide citation)

Therapeutic drug delivery systems comprising gas-filled microspheres comprising a therapeutic are described. Methods for employing such microspheres in therapeutic drug delivery applications are also provided. Drug delivery systems comprising gas-filled liposomes having encapsulated therein a drug a ...


9
Evan C Unger: Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same. Woodcock Washburn Kurtz Mackiewicz & Norris, February 18, 1992: US05088499 (198 worldwide citation)

Liposomes suitable as ultrasound contrast agents which contain media of various types including gases, gaseous precursors activated by pH, temperature or pressure, as well as other solid or liquid contrast enhancing agents, are described. Methods of using the same as ultrasound contrast agents are a ...


10
Evan C Unger: Methods for providing localized therapeutic heat to biological tissues and fluids using gas filled liposomes. Woodcock Washburn Kurtz Mackiewicz & Norris, May 11, 1993: US05209720 (190 worldwide citation)

Gas filled liposomes prepared by a vacuum drying gas instillation method and/or gas filled liposomes substantially devoid of liquid in the interior thereof, are presented as novel potentiators for ultrasonic hyperthermia. The liposomes of the present invention, which may be administered into the vas ...