1
Eugene T Michal, Christopher J Buchko, Stephen J Bigus: Therapeutic, diagnostic, or hydrophilic coating for an intracorporeal medical device. Advanced Cardiovascular Systems, Heller Ehrman White & McAuliffe, September 11, 2001: US06287285 (190 worldwide citation)

A method of providing a therapeutic, diagnostic or lubricious hydrophilic coating on an intracorporeal medical device and the coated device produced thereby, wherein the coating is durable. In one embodiment, the coating comprises a polymerized base coat and a therapeutic, diagnostic or hydrophilic ...


2
Wouter E Roorda, Ni Ding, Stephen D Pacetti, Eugene T Michal, Ashok A Shah, Syed F A Hossainy: Polyacrylates coatings for implantable medical devices. Advanced Cardiovascular Systems, Squire Sanders & Dempsey L, July 24, 2007: US07247313 (96 worldwide citation)

A coating for a medical device, particularly for a drug eluting stent, is described. The coating can include a polyacrylate, a blend of polyacrylates, or a blend of the polyacrylate with other polymers, for example, poly(ethylene-co-vinyl alcohol).


3
Eugene T Michal, Jeffrey Ross: Methods and compositions to treat myocardial conditions. Advanced Cardiovascular Systems, Blakely Sokoloff Taylor & Zafman, November 13, 2007: US07294334 (77 worldwide citation)

Methods, devices, kits and compositions to treat a myocardial infarction. In one embodiment, the method includes the prevention of remodeling of the infarct zone of the ventricle using a combination of therapies. The method may include the introduction of structurally reinforcing agents. In other em ...


4
Syed F A Hossainy, Eugene T Michal, Charles D Claude: Biocompatible carrier containing L-arginine. Advanced Cardiovascular Systems, Squire Sanders & Dempsey, February 7, 2006: US06994867 (76 worldwide citation)

L-arginine conjugated to a polymeric matrix is disclosed. The matrix can be used as, for example, a coating for an implantable medical device such as a stent.


5
Eugene T Michal, Christopher J Buchko, Deborah L Kilpatrick, Stephen J Bigus: Superoxide dismutase or superoxide dismutase mimic coating for an intracorporeal medical device. Advanced Cardiovascular Systems, Filwider Patton Lee & Utecht, April 1, 2003: US06541116 (69 worldwide citation)

A method of providing a therapeutic, diagnostic or lubricious hydrophilic coating on an intracorporeal medical device and the coated device produced thereby, wherein the coating is durable. In one embodiment, the coating comprises a polymerized base coat and a top coat having a therapeutic, diagnost ...


6
Evgenia Mandrusov, Murthy V Simhambhatla, Syed Hossainy, Eugene T Michal, Charles Claude, Jessica G Chiu: Agents that stimulate therapeutic angiogenesis and techniques and devices that enable their delivery. Advanced Cardiovascular Systems, Blakely Sokoloff Taylor & Zafman, March 9, 2004: US06702744 (66 worldwide citation)

A method including positioning a catheter at a location in a blood vessel; imaging a thickness of a portion of a wall of the blood vessel at the location; identifying a treatment site; advancing a needle a distance into the wall of the blood vessel to the treatment site; and introducing a treatment ...


7
Eugene T Michal, Christopher J Buchko, Stephen J Bigus: Therapeutic, diagnostic, or hydrophilic coating for an intracorporeal medical device. Advanced Cardiovascular Systems, Fulwider Patton Lee & Utecht, December 2, 2003: US06656517 (63 worldwide citation)

A method of providing a therapeutic, diagnostic or lubricious hydrophilic coating on an intracorporeal medical device and the coated device produced thereby, wherein the coating is durable. In one embodiment, the coating comprises a polymerized base coat and a therapeutic, diagnostic or hydrophilic ...


8
Ashok A Shah, Eugene T Michal: Coatings for implantable medical device containing polycationic peptides. Advanced Cardiovascular Systems, Squire Sanders & Dempsey L, August 22, 2006: US07094256 (61 worldwide citation)

Coatings for implantable medical devices and methods for fabricating the same are disclosed. The coatings include carboxylated acrylates and polycationic peptides, for example R7.


9
Charles D Claude, Syed F A Hossainy, Eugene T Michal: Biocompatible coating for implantable medical devices. Advanced Cardiovascular Systems, Squire Sanders & Dempsey, August 17, 2010: US07776926 (53 worldwide citation)

A random or a block copolymer which includes at least one biologically compatible structural moiety and at least one biologically active moiety is disclosed. The random or block copolymer can be used for fabricating a coating for an implantable medical device such as a stent.


10
Syed F A Hossainy, Eugene T Michal, Yiwen Tang: Biologically absorbable coatings for implantable devices and methods for fabricating the same. Advanced Cardiovasular Systems, Squire Sanders & Dempsey L, January 30, 2007: US07169404 (38 worldwide citation)

Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising a biologically degradable, biologically erodable, and/or biologically resorbable ABA or AB block copolymer. A biologically active agent can be conjugated to the block copolymer.