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Ernst B Hunziker: Method and compositions for the treatment and repair of defects or lesions in cartilage. Robert F Shaw, James F Haley Jr, Jane A Massaro, April 27, 1993: US05206023 (358 worldwide citation)

Methods and compositions are provided for the treatment and repair of defects or lesions in the cartilage of humans and other animals. The defect or lesion in the cartilage may be first treated with an enzyme to remove proteoglycans from the defect area. To induce cartilage formation, the defect is ...


2
Ernst B Hunziker: Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone. Robert Francis Shaw, Edward F Mullowney, Jane A Massaro, December 14, 1993: US05270300 (280 worldwide citation)

Methods and compositions are provided for the treatment and repair of defects in the cartilage or bone of humans and other animals as in full-thickness defects in joints. The defect in bone is filled with a matrix having pores large enough to allow cells to populate the matrix and to form blood vess ...


3
Ernst B Hunziker: Methods and compositions for the treatment and repair of defects or lesions in cartilage. Robert F Shaw, James F Haley Jr, Jane A Massaro, November 29, 1994: US05368858 (273 worldwide citation)

Methods and compositions are provided for the treatment and repair of defects or lesions in the cartilage of humans and other animals. The defect or lesion in the cartilage may be first treated with an enzyme to remove proteoglycans from the defect area. To induce cartilage formation, the defect is ...


4
Ernst B Hunziker: Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone using functional barrier. Robert Francis Shaw, Jane A Massaro, Mark J Rosen, Fish & Neave, December 29, 1998: US05853746 (161 worldwide citation)

Methods and compositions are provided for the treatment and repair of defects in the cartilage or bone of humans and other animals as in full-thickness defects in joints. To induce cartilage formation, a defect in cartilage is filled with a matrix having pores sufficiently large to allow cartilage r ...


5
Kay Juergensen, Daniel Aeschlimann, Ernst B Hunziker: Biological adhesive composition and method of promoting adhesion between tissue surfaces. Orthogene, Wood Herron & Evans P L L, August 27, 1996: US05549904 (117 worldwide citation)

A formulated biological adhesive composition utilizes tissue transglutaminase in a pharmaceutically acceptable aqueous carrier. The tissue transglutaminase is used in an effective catalytic amount to promote adhesion between tissue surfaces upon treatment thereof by catalyzing the reaction between g ...


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Kay Juergensen, Daniel Aeschlimann, Ernst B Hunziker: Method of promoting adhesion between tissue surfaces. Orthogene, Wood Herron & Evans L, April 7, 1998: US05736132 (83 worldwide citation)

A formulated biological adhesive composition utilizes tissue transglutaminase in a pharmaceutically acceptable aqueous carrier. The tissue transglutaminase is used in an effective catalytic amount to promote adhesion between tissue surfaces upon treatment thereof by catalyzing the reaction between g ...


7
Ernst B Hunziker: Compositions and methods for the treatment and repair of defects or lesions in articular cartilage using synovial-derived tissue or cells. Orthogene, Ropes & Gray, August 18, 2009: US07575743 (4 worldwide citation)

Compositions and methods are provided for treatment of cartilage defects in animals and humans. The compositions of the invention include synovial tissue, synovial cells and matrices containing synovial (or cambium) tissue or cells for use in filling a cartilage defect. The matrix and synovial tissu ...


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Ernst B Hunziker: Compositions and methods for the treatment and repair of defects or lesions in articular cartilage using synovial-derived tissue or cells. Ropes & Gray, Patent Docketing 39 41, February 14, 2008: US20080039955-A1

Compositions and methods are provided for treatment of cartilage defects in animals and humans. The compositions of the invention include synovial tissue, synovial cells and matrices containing synovial (or cambium) tissue or cells for use in filling a cartilage defect. The matrix and synovial tissu ...


10
Ernst B Hunziker: Compositions and methods for the treatment and repair of defects or lesions in articular cartilage using synovial-derived tissue or cells. Ropes & Gray, Patent Docketing 39 41, February 14, 2008: US20080038314-A1

Compositions and methods are provided for treatment of cartilage defects in animals and humans. The compositions of the invention include synovial tissue, synovial cells and matrices containing synovial (or cambium) tissue or cells for use in filling a cartilage defect. The matrix and synovial tissu ...