1
Ernest G Tickner, Ned S Rasor: Ultrasonic image enhancement. Rasor Associates, Phillips Moore Weissenberger Lempio & Majestic, July 7, 1981: US04276885 (294 worldwide citation)

Ultrasonic images of flowing streams can provide important information regarding the streams. Herein, a plurality of microbubbles are provided in such streams to enhance such images, aid in tumor detection and treatment, provide mapping of vascularity of tissue masses and measure instantaneous blood ...


2
Julia S Rasor, Ernest G Tickner: Microbubble precursors and apparatus for their production and use. Schering Aktiengesellschaft, Millen & White, April 14, 1987: US04657756 (219 worldwide citation)

Microbubbles are formed in a liquid, e.g., blood in order to alter the transmission characteristics thereof to electromagnetic and sonic waves transmitted therethrough, by dissolving therein a solid particulate material, preferably as a suspension in a carrier liquid in which the particulate materia ...


3
Julia S Rasor, Ernest G Tickner: Microbubble precursors and methods for their production and use. Schering, Millen & White, April 17, 1984: US04442843 (201 worldwide citation)

Microbubbles are formed in a liquid, e.g., blood in order to alter the transmission characteristics thereof to electromagnetic and sonic waves transmitted therethrough, by dissolving therein a solid particulate material, preferably as a suspension in a carrier liquid in which the particulate materia ...


4
Julia S Rasor, Ernest G Tickner: Method of production and use of microbubble precursors. Schering Aktiengesellschaft, Millen & White, July 21, 1987: US04681119 (189 worldwide citation)

In the inventive method, microbubbles are formed in body liquid or carrier liquid, for example within the genitourinary or digestive systems in order to alter the transmission characteristics thereof to electromagnetic and sonic waves transmitted therethrough, by dissolving therein a solid particula ...


5
Ernest G Tickner: Method of determining pressure within liquid containing vessel. Rasor Associates, Phillips Moore Weissenberger Lempio & Majestic, May 5, 1981: US04265251 (122 worldwide citation)

Pressure within a liquid containing vessel is determined by adding a solid precursor for at least one bubble to the liquid, retaining the precursor in the liquid for a sufficient time for it to form at least one bubble and generate a sonic signal, metering a characteristic of the sonic signal which ...


6
Ernest G Tickner: Flow rate measurement. Ultra Med, Phillips Moore Weissenberger Lempio & Majestic, February 23, 1982: US04316391 (41 worldwide citation)

A method is presented for measuring fluid flow rate in a system having a conduit through which the fluid flows. The method is particularly useful for measuring blood flow rate in a cardiovascular system. A substance which provides a plurality of microbubbles is added to the fluid flow system upstrea ...


7
Ernest G Tickner, Robert E Short, David H Rammler: Microparticles as ultrasonic contrast media. Delineate, Bertram I Rowland, August 2, 1994: US05333613 (28 worldwide citation)

Ultrasonic contrast media are provided comprising small particles with entrapped gas, where the compositions can be selected for rapid dissolution with production of microbubbles or maintaining the gas in microtubules, microchambers or microcracks, providing for echogenicity. The particles are readi ...



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