1
Andrew G C Frazier, Erik J van der Burg, Michael D Lesh: Method and apparatus for closing a body lumen. Appriva Medical, Knobbe Martens Olson & Bear, May 15, 2001: US06231561 (615 worldwide citation)

Disclosed is a closure catheter, for closing a body cavity such as a vessel, or the left atrial appendage of the heart. The closure catheter includes a plurality of deployable tissue anchors, which may be laterally deployed into surrounding tissue. The anchors may thereafter be used to draw the tiss ...


2
Michael D Lesh, Erik J van der Burg: Method and device for left atrial appendage occlusion. Appriva Medical, Knobbe Martens Olson & Bear, November 28, 2000: US06152144 (558 worldwide citation)

A device and method for obliterating or occluding a body cavity or passageway, in particular, the left atrial appendage of a patient's heart. The procedure can be carried out intraoperatively, but is preferably carried out percutaneously by use of a delivery catheter to position an occluding device ...


3
Chad C Roue, Andrew G C Frazier, Michael D Lesh, Erik J van der Burg: Method and apparatus for closing intracardiac septal defects. Appriva Medical, Knobbe Martens Olson & Bear, September 18, 2001: US06290674 (522 worldwide citation)

Disclosed is a closure catheter, for closing a tissue opening such as an atrial septal defect, patent foreman ovale, or the left atrial appendage of the heart. The closure catheter carries a plurality of tissue anchors, which may be deployed into tissue surrounding the opening, and used to draw the ...


4
Andrew G C Frazier, Michael D Lesh, Chad C Roue, Erik J van der Burg: Method and apparatus for patching a tissue opening. Appriva Medical, Knobbe Martens Olson & Bear, July 16, 2002: US06419669 (416 worldwide citation)

Disclosed is a closure catheter, for patching a tissue opening such as an atrial septal defect, patent foreman ovale, or the left atrial appendage of the heart. The closure catheter carries a deployable patch and a plurality of tissue anchors, which may be deployed to secure the patch to surrounding ...


5
Andrew G C Frazier, Michael D Lesh, Chad C Roue, Erik J van der Burg: Transluminal anastomosis method and apparatus. Appriva Medical, Knobbe Martens Olson & Bear, December 11, 2001: US06328727 (390 worldwide citation)

Disclosed is an anastomosis catheter, for achieving a tissue to tissue or synthetic graft to tissue attachment. The catheter includes a plurality of deployable tissue anchors, which may be laterally deployed into surrounding tissue. The anchors may be used to achieve end to end or end to side anasto ...


6
Andrew G C Frazier, Michael D Lesh, Chad C Roue, Erik J van der Burg: Method and apparatus for closing a subcutaneous tissue opening. Appriva Medical, Knobbe Martens Olson & Bear, August 20, 2002: US06436088 (219 worldwide citation)

Disclosed is a closure catheter, for patching a tissue opening such as an atrial septal defect, patent foreman ovale, or the left atrial appendage of the heart. The closure catheter carries a deployable patch and a plurality of tissue anchors, which may be deployed to secure the patch to surrounding ...


7
Andrew G C Frazier, Michael D Lesh, Chad C Roue, Erik J van der Burg: Endoluminal anchor. ev3 Sunnyvale, Knobbe Martens Olson & Bear, June 8, 2004: US06746472 (194 worldwide citation)

Disclosed is an anastomosis catheter, for achieving a tissue to tissue or synthetic graft to tissue attachment. The catheter includes a plurality of deployable tissue anchors, which may be laterally deployed into surrounding tissue. The anchors may be used to achieve end to end or end to side anasto ...


8
Chad C Roue, Andrew G C Frazier, Michael D Lesh, Erik J van der Burg: Method of closing an opening in a wall of the heart. EV3 Sunnyvale, Knobbe Martens Olson & Bear, March 30, 2004: US06712804 (192 worldwide citation)

Disclosed is a closure catheter, for closing a tissue opening such as an atrial septal defect, patent foreman ovale, or the left atrial appendage of the heart. The closure catheter carries a plurality of tissue anchors, which may be deployed into tissue surrounding the opening, and used to draw the ...


9
Erik J van der Burg, Dino De Cicco, Andrew G C Frazier, Alex K Khairkahan, Marc S Kriedler, Michael D Lesh, Chad C Roue: Method and device for left atrial appendage occlusion. ev3 Endovascular, Knobbe Martens Olson & Bear, October 31, 2006: US07128073 (186 worldwide citation)

Disclosed is an occlusion device for use in a body lumen such as the left atrial appendage. The occlusion device includes an occlusion member and may also include a stabilizing member. The stabilizing member inhibits compression of the left atrial appendage, facilitating tissue in-growth onto the oc ...


10
Michael D Lesh, Alex K Khairkahan, Erik J van der Burg: Method for accessing the left atrium of the heart by locating the fossa ovalis. ev3 Sunnyvale, Knobbe Martens Olson & Bear, November 18, 2003: US06650923 (173 worldwide citation)

Disclosed is an access catheter for identifying and providing access through a tissue structure such as the fossa ovalis on the intraatrial septum. The access catheter comprises an elongate flexible tubular body having a proximal and a distal end, and a retractable piercing structure such as a needl ...



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