1
Wolfgang Fink, Eui Hyeok Yang, Yoshi Hishinuma, Choonsup Lee, Thomas George, Yu Chong Tai, Ellis Meng, Mark Humayun: Optically powered and optically data-transmitting wireless intraocular pressure sensor device. California Institute of Technology, Doheny Eye Institute, Fish & Neave IP Group, November 7, 2006: US07131945 (118 worldwide citation)

An implantable intraocular pressure sensor device for detecting excessive intraocular pressure above a predetermined threshold pressure is disclosed. The device includes a pressure switch that is sized and configured to be placed in an eye, wherein said pressure switch is activated when the intraocu ...


2
Yu Chong Tai, Ellis Meng, Po Jui Chen, Damien C Rodger, Mark Humayun: Implantable mechanical pressure sensor and method of manufacturing the same. California Institute of Technology, Christie Parker & Hale, August 7, 2007: US07252006 (53 worldwide citation)

A biocompatible, mechanical, micromachined pressure sensor and methods of manufacturing such a pressure sensor are provided. The pressure sensor of the current invention includes a high-aspect-ratio curved-tube structure fabricated through a one-layer parylene process. The pressure sensor of the cur ...


3
Ellis Meng, Yu Chong Tai, Mark S Humayun, Rajat Agrawal, Ronalee Lo, Jason Shih, Kenrick Kuwahara, Po Ying Li, Damien Rodger, Po Jui Chen: MEMS device and method for delivery of therapeutic agents. The University of Southern California, Goodwin Procter, February 15, 2011: US07887508 (40 worldwide citation)

Embodiments of an implantable device for delivering a therapeutic agent to a patient includes a reservoir configured to contain a liquid comprising the therapeutic agent and a cannula in fluid communication with the reservoir. The device and related methods may provide such features as constant-flow ...


4
Yu Chong Tai, Ellis Meng, Xuan Qi Wang, Charles Grosjean: Check-valved silicon diaphragm pump and method of fabricating the same. California Institute of Technology, Daniel L Dawes Esq, Myers Dawes & Andras, January 1, 2002: US06334761 (18 worldwide citation)

A silicone rubber diaphragm pump utilizing a pair of MEMS Parylene check valves and a miniature solenoid plunger and actuator is comprised of a spacer sandwiched by a silicone rubber diaphragm on one side and a check valve support on the other. The check valves in the check valve support form the in ...


5
Ellis Meng, Yu Chong Tai, Mark Humayun, Rajat Agrawal, Ronalee Lo, Jason Shih, Kenrick Kuwahara, Po Ying Li, Damien Rodger, Po Jui Chen: MEMS device and method for delivery of therapeutic agents. The University of Southern California, Bingham McCutchen, November 13, 2012: US08308686 (8 worldwide citation)

Embodiments of an implantable device for delivering a therapeutic agent to a patient include a reservoir configured to contain a liquid comprising the therapeutic agent, and a cannula in fluid communication with the reservoir. The cannula is shaped to facilitate insertion thereof into a patient's ey ...


6
Ellis Meng, Ronalee Lo Mann: Drug delivery device with in-plane bandpass regulation check valve in heat-shrink packaging. University of Southern California, McDermott Will & Emery, February 12, 2013: US08372046 (2 worldwide citation)

A drug delivery device may include a drug reservoir configured to contain and controllably deliver a fluidic drug. A tube may be configured to deliver the fluid from the drug reservoir through a lumen in the tube to another location. A valve wholly within the lumen of the tube may regulate the flow ...


7
Christian A Gutierrez, Ellis Meng: Microelectromechanical (MEMS) pressure transducer. University of Southern California, McDermott Will & Emery, July 23, 2013: US08490497 (1 worldwide citation)

A pressure transducer for measuring pressure may include an all-polymer chamber that has no dimension greater than 1 mm. There may be fluid within the chamber, a gaseous bubble trapped within the fluid, and electrodes in contact with the fluid. The electrodes may enable a measurement of changes in t ...


8
Ellis Meng, Ronalee Lo: Interconnect for MEMS device including a viscoelastic septum. Stetina Brunda Garred & Brucker, January 3, 2012: US08087310 (1 worldwide citation)

Provided is a micro electro mechanical systems (MEMS) device for use with an elongate structure. The MEMS device includes a generally planar substrate, a device wall layer formed upon the substrate, a septum cavity formed in the device wall layer, a channel formed in the device wall layer in fluid c ...


9
Christian A Gutierrez, Ellis Meng: Tracking and controlling fluid delivery from chamber. UNIVERSITY OF SOUTHERN CALIFORNIA, McDermott Will & Emery, December 29, 2015: US09222819

Electrochemical impedance may be used for accurate and real-time tracking and control of fluid delivery from fluid-filled chambers, such as from drug delivery devices. At least two measurement electrodes may be placed within the chamber in contact with the fluid to be sensed. Application of a small ...


10
Ellis Meng: MEMS electrochemical bellows actuator. University of Southern California, McDermott Will & Emery, November 12, 2013: US08579885

An implantable fluid delivery system may include a fluid reservoir configured to hold a supply of fluid, dispense that fluid under the control of an actuator, and be implanted within the body of a living host. The actuator may include a bellows configured to expand in a direction when inflated. The ...