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Effland Richard Charles, Klein Joseph Thomas: N-(pyridinyl)-1h-indol-1-amines, a process for their preparation and their use as medicaments.. Hoechst Roussel Pharma, October 26, 1988: EP0287982-A2 (28 worldwide citation)

There are disclosed compounds of the formula where m is 1 or 2; n is 1 or 2; P is 0 or 1; each R is independently hydrogen, halogen, loweralkyl, loweralkoxy, hydroxy, nitro, amino, loweralkylamino, loweralkylcarbonylamino, cyano, formyl, loweralkoxycarbonyl, loweralkylthio or loweralkoxycarbonyllowe ...


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Effland Richard Charles, Klein Joseph Thomas: Alpha-alkyl-4-amino-3-quinoline-methanols and 1-(4-aralkylamino-3-quinolinyl) alkanones, a process for their preparation and their use as medicaments.. Hoechst Roussel Pharma, March 9, 1988: EP0258755-A1 (26 worldwide citation)

There are described compounds of the formula where X is hydrogen, halogen, loweralkyl, loweralkoxy or trifluoromethyl; R is - @-R4 or -@@-R4, R4 being loweralkyl; R1 is hydrogen, loweralkyl or arylloweralkyl; R2 is hydrogen, loweralkyl or arylloweralkyl; and R3 is loweralkyl, with the proviso that w ...


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Effland Richard Charles, Klein Joseph Thomas, Olsen Gordon Edward, Davis Larry, Hamer Russell Richard Lee, Freed Brain Scott: Heteroarylamino- and heteroaryloxypyridinamines and related compounds, a process for their preparation and their use as medicaments.. Hoechst Roussel Pharma, January 2, 1991: EP0405425-A2 (21 worldwide citation)

There are described compounds of the formula where n is 0 or 1; X is O or NR2, R2 being hydrogen, loweralkyl or loweralkylcarbonyl; Z is NO2 or NHR where R is hydrogen, loweralkyl, arylloweralkyl or loweralkylcarbonyl; and R1 is wherein R3 is hydrogen, loweralkyl or loweralkylcarbonyl; m is 1 or 2; ...


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Effland Richard Charles, Klein Joseph Thomas, Martin Lawrence Leo: Substituted 3-(pyridinylamino)-indoles and benzo[b]thiophenes, a process for their preparation and their use as medicaments.. Hoechst Roussel Pharma, October 21, 1992: EP0509402-A1 (11 worldwide citation)

The present invention relates to compounds of the formula I where R1 is hydrogen, loweralkyl, loweralkenyl, loweralkynyl, arylloweralkyl, aminoloweralkyl, loweralkylaminoloweralkyl, formyl, loweralkylcarbonyl, aminoloweralkylcarbonyl or loweralkoxycarbonyl; the group -X-Y= is R2 and R3 being indepen ...


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Kosley Raymond W Jr, Spahl Bettina, Effland Richard Charles: (1-indanon-2yl)methylpiperidines, intermediates and a process for their preparation and their use as medicaments.. Hoechst Roussel Pharma, April 7, 1993: EP0535496-A1 (9 worldwide citation)

The present invention relates to (1indanon-2-yl)methylpiperidines of the formula wherein R is hydrogen, loweralkyl, or a group of the formula R is hydrogen or a group of the formula W, X, and Y are hydrogen, loweralkyl, loweralkoxy, halogen, nitro, or trifluoromethyl; n is 1 or 2; the optical isomer ...


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Effland Richard Charles, Strupczewski Joseph Thomas, Gardner Beth Ann: Spiro-(dihydrobenzofuranpiperidines and -pyrrolidines) and derivatives thereof, methods for their preparation and medicines containing them.. Hoechst, October 31, 1979: EP0004952-A1 (8 worldwide citation)

Verbindungen der Formel worin X Wasserstoff, Nitro, Amino, Chlor, Fluor, Brom oder Methoxy R Wasserstoff, Alkyl, Alkenyl, Hydroxy├Ąthyl, Alkanoyl, Alkoxyoxalyl, unsubstituiertes oder substituiertes Phenylalkanoyl, unsubstituiertes oder substituiertes Benzoyl, unsubstituiertes oder substituiertes Phen ...


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Davis Larry, Effland Richard Charles, Klein Joseph Thomas: 1-(3-(6-fluoro-1,2-benzisoxasol-3-yl)propyl)-4-hydroxy-4-phenylpiperidines, a process for their preparation and their use as medicaments.. Hoechst Roussel Pharma, November 3, 1982: EP0063799-A2 (8 worldwide citation)

1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-hydroxy-4-penylpiperidi nes, of formula: wherein X is hydrogen, loweralkyl, loweralkoxy, halogen or trifluoromethyl; Y is hydrogen or trifluoromethyl with the proviso that Y is hydrogen when X is hydrogen, loweralkyl, loweralkoxy or trifluoromethyl and ...


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Effland Richard Charles Dr, Wettlaufer David Gordon Dr: 1-(pyridinylamino)-2-pyrrolidinones, a process for their preparation and their use as medicaments.. Hoechst Roussel Pharma, February 20, 1991: EP0413191-A1 (7 worldwide citation)

This invention relates to 1-(pyridinylamino)-2-pyrrolidinones of the formula wherein R1, R2 and R3 are independently hydrogen, loweralkyl, aryl, arylloweralkyl or heteroarylloweralkyl selected from the group consisting of pyridinylmethyl, pyridinylethyl, thienylmethyl, thienylethyl or R2 and R3 toge ...


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Effland Richard Charles Dr, Wettlaufer David Gordon Dr: 1,3-dihydro-1-(pyridinylamino)-2h-indol-2-ones, a process for their preparation and their use as medicaments.. Hoechst Roussel Pharma, March 6, 1991: EP0415102-A1 (7 worldwide citation)

This invention relates to 1,3-dihydro-1-(pyridinylamino)-2H-indol-2-ones of the formula where R1, R2 and R3 are independently hydrogen, loweralkyl, aryl, arylloweralkyl or heteroarylloweralkyl selected from the group consisting of pyridinylmethyl, pyridinylethyl, thienylmethyl, thienylethyl; or R2 a ...