1
Edward T Maggio: Kit for carrying out chemically induced fluorescence immunoassay. Syva Company, Bertram I Rowland, July 7, 1981: US04277437 (377 worldwide citation)

A competitive protein binding method is provided for the determination of an analyte which is a member of an immunological pair consisting of ligand and receptor for the ligand. A chemiluminescent source is employed comprised of one or more individual members, one chemiluminescent source member bein ...


2
Edward T Maggio, Richard L Wife, Edwin F Ullman: Reagents and method employing channeling. Syva Company, Bertram I Rowland, November 11, 1980: US04233402 (182 worldwide citation)

Method and compositions are provided for chemical analysis of an analyte which is a member of a specific binding pair of organic substances consisting of ligand and ligand receptor (antiligand). The method involves bringing together the following reagents with the analyte in an aqueous assay medium ...


3
Robert F Zuk, Edward T Maggio: Label modified immunoassays. Syva Company, Bertram I Rowland, June 17, 1980: US04208479 (133 worldwide citation)

Methods and reagents are provided for immunoassays employing as reagents a labelled receptor, where the label is capable of providing a detectable signal, and modifying reagents, capable of modifying the signal obtained from the label. When ligand (ligand analog for monoepitopic ligands) is present ...


4
Edward T Maggio: Chemically induced fluorescence immunoassay. Syva Company, Bertram I Rowland, September 2, 1980: US04220450 (81 worldwide citation)

A competitive protein binding method is provided for the determination of an analyte which is a member of an immunological pair consisting of ligand and receptor for the ligand. A chemiluminescent source is employed comprised of one or more individual members, one chemiluminescent source member bein ...


5
Patrick F Coleman, Edward T Maggio: Orthogonal flow immunoassays and devices. Synbiotics Corporation, Edward S Irons, January 7, 1992: US05079142 (65 worldwide citation)

Methods and composition are provided for diagnostic assays, where a sample traverses a bibulous matrix in a first plane and the flow path redirected into a second plane at a binding site, where a signal is created in relation to the presence of analyte. Various protocols may be employed where compon ...


6
Edward T Maggio: Immunoassay incubation device. Synbiotics Corporation, Martin A Voet, August 22, 1989: US04859610 (53 worldwide citation)

An immunoassay incubation device is employed for detecting the presence of specific analytes in solid and semisolid compositions using solid phase immunoassay methods. Analysis of such compositions by solid phase immunoassay first requires that soluble or particulate analytes be extracted from the s ...


7
Janet H Chen, Edward T Maggio, Dietrich Rehbinder: Double tagged immunoassay. International Diagnostic Technology, Limbach Limbach & Sutton, May 24, 1983: US04385126 (47 worldwide citation)

Immunoassays are performed with two different ligands tagged with two different tagging constituents which are independent of each other and the two tagged ligands are immunologically bound together. The two different ligands may be detected independently through their independent tagging constituen ...


8
Valeri I Karlov, Bernard Kasten, Carlos E Padilla, Edward T Maggio, Frank Billingsley: Diagnosing inapparent diseases from common clinical tests using Bayesian analysis. Quest Diagnostics Investments Incorporated, Perseus Soros Pharmaceutical Fund, Foley & Lardner, June 24, 2008: US07392199 (31 worldwide citation)

A system and method of diagnosing diseases from biological data is disclosed. A system for automated disease diagnostics prediction can be generated using a database of clinical test data. The diagnostics prediction can also be used to develop screening tests to screen for one or more inapparent dis ...


9
Edward T Maggio: Means for monitoring the status of control of ketoacidosis-prone diabetics. August 9, 1983: US04397956 (30 worldwide citation)

Method and test system for monitoring the status of control of ketoacidosis-prone diabetics using pseudo-kinetic methods. Pseudo-kinetic clinical information is obtained by analysis of a single blood sample in which the blood glucose level is determined along with one or more additional indicator an ...


10
Robert A Yoshida, Edward T Maggio: Antienzyme homogeneous competitive binding assay. Syva Company, Bertram I Rowland, November 11, 1980: US04233401 (23 worldwide citation)

Methods and reagent combinations are provided for competitive protein binding assays for determining a member of an immunological pair (ligand and receptor) whereby an enzyme-ligand conjugate is employed in combination with an enzyme inhibitor, conveniently an antibody to said enzyme. When ligand is ...