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James Aggen, John H Griffin, Mathai Mammen, Daniel Marquess, Edmund J Moran, David Oare: Muscarinic receptor antagonists. Theravance, Jeffrey A Hagenah, Joyce G Cohen, February 17, 2004: US06693202 (123 worldwide citation)

Disclosed are multibinding compounds which are muscarinic receptor antagonists. The multibinding compounds of this invention containing from 2 to 10 ligands covalently attached to one or more linkers. Each ligand is, independently of each other, a muscarinic receptor antagonist or an allosteric modu ...


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Edmund J Moran, Seok Ki Choi: &bgr;2-adrenergic receptor agonists. Theravance, David E Boone, Jeffrey A Hagenah, Roberta P Saxon, April 1, 2003: US06541669 (54 worldwide citation)

Disclosed are multibinding compounds which are &bgr;2 adrenergic receptor agonists and are useful in the treatment and prevention of respiratory diseases such as asthma, bronchitis. They are also useful in the treatment of nervous system injury and premature labor.


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Edmund J Moran, John H Griffin, Seok Ki Choi: &bgr;2-adrenergic receptor agonists. Theravance, David E Boone, Jeffrey A Hagenah, Roberta P Saxon, June 10, 2003: US06576793 (48 worldwide citation)

Disclosed are multibinding compounds which are &bgr;2 adrenergic receptor agonists and are useful in the treatment and prevention of respiratory diseases such as asthma and bronchitis. They are also useful in the treatment of nervous system injury and premature labor.


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Edmund J Moran, John H Griffin, Seok Ki Choi: &bgr;2- adrenergic receptor agonists. Advanced Medicine, David E Boone, Jeffrey A Hagenah, March 26, 2002: US06362371 (28 worldwide citation)

The present invention is directed to multibinding compounds which are &bgr;2 adrenergic receptor agonists and are therefore useful in the treatment and prevention of respiratory diseases such asthma, bronchitis, and the like. They are also useful in the treatment of nervous system injury and prematu ...


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Seok Ki Choi, Edmund J Moran: &bgr;2-adrenergic receptor agonists. Theravance, Jeffrey A Hagenah, Roberta P Saxon, Joyce G Cohen, July 15, 2003: US06593497 (27 worldwide citation)

The present invention is directed to multibinding compounds which are &bgr;2 adrenergic receptor agonists and are therefore useful in the treatment and prevention of respiratory diseases such asthma, bronchitis, and the like. They are also useful in the treatment of nervous system injury and prematu ...


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Edmund J Moran, Seok Ki Choi: &bgr;2-adrenergic receptor agonists. Theravance, Roberta P Saxon, Jeffrey A Hagenah, Joyce G Cohen, March 30, 2004: US06713651 (24 worldwide citation)

Disclosed are multibinding compounds which are &bgr;2-adrenergic receptor agonists and are useful in the treatment and prevention of respiratory diseases such as asthma, and bronchitis. They are also useful in the treatment of nervous system injury and premature labor.


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Paul R Fatheree, Martin S Linsell, Daniel Marquess, Sean G Trapp, Edmund J Moran, James B Aggen: Cross-linked glycopeptide-cephalosporin antibiotics. Theravance, Jeffrey A Hagenah, June 27, 2006: US07067482 (23 worldwide citation)

This invention provides cross-linked glycopeptide—cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using suc ...



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