1
Nelson H Ludwig, Earl E Ose: Controlled release formulations and method of treatment. Eli Lilly and Company, Charles W Ashbrook, Arthur R Whale, October 6, 1981: US04293539 (148 worldwide citation)

Controlled release formulations useful in the prolonged treatment and control of microbial infections in animals are comprised of a microbial agent intimately dispersed throughout a copolymer derived from lactic acid and glycolic acid. A method for providing protection to animals for extended period ...


2
Earl E Ose, Herbert A Kirst: Methods of controlling Pasteurella infections. Eli Lilly and Company, Nancy J Harrison, Arthur R Whale, November 2, 1982: US04357325 (10 worldwide citation)

Methods of controlling Pasteurella infections are provided which comprise administering to an infected or susceptible warm-blooded aninal an effective amount of a composition comprising (1) a suitable pharmaceutical vehicle and (2) a compound selected from the group consisting of desmycosin, lacteno ...


3
Earl E Ose, Herbert A Kirst: Method of controlling ureaplasma infections. Eli Lilly and Company, Nancy J Harrison, Arthur R Whale, July 27, 1982: US04341770 (6 worldwide citation)

Method of controlling Ureaplasma infections which comprises administering to an infected or susceptible warm-blooded animal an effective amount of 5-0-mycaminosyl tylonolide or a pharmaceutically acceptable acid addition salt thereof.


4
Herbert A Kirst, Earl E Ose: Method of controlling Pasteurella infections. Eli Lilly and Company, Nancy J Harrison, Arthur R Whale, July 27, 1982: US04341771 (2 worldwide citation)

Method of controlling Pasteurella infections which comprises administering to an infected or susceptible warm-blooded animal an effective amount of 5-O-mycaminosyl tylonolide or a pharmaceutically acceptable acid addition salt thereof.


5
Earl E Ose: Method for treating colibacillosis in pigs with tylosin apramycin compositions. Eli Lilly and Company, William B Scanlon, Arthur R Whale, August 11, 1981: US04283388 (1 worldwide citation)

Antibiotic compositions comprising tylosin and apramycin are effective in the treatment and control of colibacillosis in weanling pigs, and demonstrate greater effectiveness than apramycin alone or tylosin alone.


6
Ronald D Johnson, Ralph M Kastner, Stephen H Larsen, Earl E Ose: Process for production antibiotic A53868. Eli Lilly and Company, Nancy J Harrison, Arthur R Whale, July 31, 1984: US04463092

Antibiotic A53868 factor A, which is N.sup.2 -glycyl-N-(2-methylene-2-phosphonoethyl)leucinamide, and the formula: ##STR1## and the salts thereof, which are useful as antibiotics or as intermediates to antibiotics; methods of preparing A53868 factor A by fermentation of Streptomyces luridus; and the ...


7
Ronald D Johnson, Ralph M Kastner, Stephen H Larsen, Earl E Ose: Antibiotic A53868 and process for production thereof. Eli Lilly and Company, Nancy J Harrison, Arthur R Whale, November 13, 1984: US04482488

Antibiotic A53868 factor A, which is N.sup.2 -glycyl-N-(2-methylene-2-phosphonoethyl)leucinamide, and the formula: ##STR1## and the salts thereof, which are useful as antibiotics or as intermediates to antibiotics; methods of preparing A53868 factor A by fermentation of Streptomyces luridus; and the ...


8
Earl E Ose, Jan R Turner: Methods of controlling mycoplasma infections. Eli Lilly and Company, Nancy J Harrison, Arthur R Whale, June 10, 1986: US04594337

Methods of controlling Mycoplasma infections which comprise administering to an infected or susceptible warm-blooded animal an effective amount of a new macrocin or lactenocin ester derivative of the formula: ##STR1## wherein R is formyl or hydroxymethyl; R.sup.1 is hydrogen, acetyl or propionyl; R. ...


9
Earl E Ose: Control of swine dysentery. Eli Lilly and Company, Leroy Whitaker, Arthur R Whale, March 13, 1984: US04436734

The antibiotic, avilamycin, is useful in the treatment or prevention of swine dysentery.


10
Earl E Ose: Therapeutic for gram-positive diseases of aquatic species. Eli Lilly And Company, WU XIAONAN, October 12, 1994: CN93121623

The invention is directed to the use of tilmicosin and other compounds of U.S. Patent 4,820,695 for the treatment of gram-positive bacterial pathogens in aquatic species.