1
Douglas P Zipes: Synchronous intracardiac cardioverter. Medtronic, Robert C Beck, John L Rooney, Joseph F Breimayer, May 24, 1983: US04384585 (178 worldwide citation)

An implantable medical device to deliver cardioverting energy to cardiac tissue in synchrony with detected ventricular depolarizations. The energy renders refractory, areas of the heart associated with a reciprocating or automatic tachycardia, thus reverting these tachyarrhythmias to normal sinus rh ...


2
Eric N Prystowsky, Douglas P Zipes: Method of inhibiting cardiac arrhythmias. Barnes & Thornburg, November 26, 1985: US04554922 (124 worldwide citation)

Inhibition of cardiac arrhythmias such as tachycardia and fibrillation is achieved by determining a refractory period after a selected heartbeat during which a stimulus applied to the heart will not propagate a heart response, determining a time within the refractory period after the selected heartb ...


3
Keith L March, Douglas P Zipes: Pericardial delivery of therapeutic and diagnostic agents. Indiana University Foundation, Elliot M Olstein, Raymond J Lillie, August 25, 1998: US05797870 (113 worldwide citation)

A method for treating a patient's heart which comprising delivering a gene therapy agent into the pericardial sac around the patient's heart. The agent is introduced surgically or by transvascular means such as a catheter which has been introduced percutaneously or otherwise. Introducing the gene th ...


4
Eran Ofek, Douglas P Zipes: Catheter with pressure sensor and guidance system. Physical Logic, Edward S Sherman, April 21, 2009: US07520858 (1 worldwide citation)

A catheter terminates at a tip that includes an array of pressure sensors. The sensors are responsive to detect and alert the user to variations of pressure that indicate the tip is either encountering an obstruction or constriction of smaller diameter than the catheter, as well as to guide the cath ...


5
Eran Ofek, Douglas P Zipes: Catheter with Pressure Sensor and Guidance System. Physical Logic, Edward S Sherman Esq, December 6, 2007: US20070282211-A1

A catheter terminates at a tip that includes an array of pressure sensors. The sensors are responsive to detect and alert the user to variations of pressure that indicate the tip is either encountering an obstruction or constriction of smaller diameter than the catheter, as well as to guide the cath ...


6
Noel Axelrod, Eran Ofek, Douglas P Zipes: Cardiac Pacemaker and/or ICD Control and Monitor. Physical Logic, Edward S Sherman Esq, September 20, 2007: US20070219592-A1

A cardiac pacemaker and/or ICD device deploys a plurality of three-dimensional accelerometers to characterize and distinguish between the local motion of the heart and the gross movement of the patient. The relative difference between these movements is used to distinguish between false negatives re ...