1
Donna L Romero, Richard C Thomas, Paul D May, Toni Jo Poel: Alkyl substituted piperadinyl and piperazinyl anti-AIDS compounds. Pharmacia & Upjohn Company, Bruce Stein, February 2, 1999: US05866589 (22 worldwide citation)

Anti-AIDS compounds of formula (I) ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, and R.sub.7 are as defined in the specification and R.sub.8 is alkyl of substituted alkyl.


2
John R Palmer, Donna L Romero, Paul A Aristoff, Richard C Thomas, Herman W Smith: Diaromatic substituted compounds as anti-HIV-1 agents. The Upjohn Company, Bruce Stein, October 8, 1996: US05563142 (9 worldwide citation)

The present invention includes diaromatic substituted heterocyclic compounds (III) ##STR1## which are useful in treating individuals infected with the HIV virus.


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Donna L Romero, Matthew David Wessel, Shaughnessy Robinson, Jeremy Robert Greenwood, Karl Shawn Watts, Leah Lynn Frye, Geraldine C Harriman, Alan Franklin Corin, Craig E Masse, Mee Shelley: IRAK inhibitors and uses thereof. Nimbus Iris, Choate Hall & Stewart, Andrea C Robidoux, Thomas H McLean, April 22, 2014: US08703941 (8 worldwide citation)

The present invention provides thienopyrimidine and thienopyridine compounds, compositions thereof, and methods of using the same for the treatment of diseases mediated by IRAK enzymes. Such diseases include inflammatory and proliferative diseases.


4
John R Palmer, Paul A Aristoff, Donna L Romero: Anti-aids piperazines. The Upjohn Company, Bruce Stein, February 6, 1996: US05489593 (6 worldwide citation)

The present invention includes diaromatic substituted heterocyclic compounds (III) ##STR1## which are useful in treating individuals infected with the HIV virus. The invention includes certain previously generically disclosed anti-AIDS piperazinyl compounds (V) and a method of treating HIV infected ...


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Donna L Romero, Shaughnessy Robinson, Matthew David Wessel, Jeremy Robert Greenwood: IRAK inhibitors and uses thereof. Nimbus Iris, Choate Hall & Stewart, Andrea L C Reid, Thomas H McLean, July 21, 2015: US09085586 (2 worldwide citation)

The present invention provides arylo-fused thienopyrimidine compounds, compositions thereof, and methods of using the same.


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John M McCall, Donna L Romero, Robert C Kelly: Substituted quinoxaline carboxylic acids for the inhibition of PASK. BioEnergenix, Dennis A Bennett, Brock Levin, December 16, 2014: US08912188 (2 worldwide citation)

Disclosed herein are substituted quinoxaline carboxylic acids of Formula (I): and compositions thereof, which may be useful as inhibitors of PAS Kinase (PASK) activity in a human or animal for the treatment of diseases such as diabetes mellitus.


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John M McCall, John McKearn, Donna L Romero, Michael Clare: Heterocyclic compounds for the inhibition of PASK. BioEnergenix, Dennis A Bennett, Brock Levin, December 23, 2014: US08916560 (2 worldwide citation)

Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibiting PAS Kinase (PASK) activity in a human or animal subject are also provided for the treatment of diseases such as diabetes mellitus.