1
Paul Goldenheim, Donna Donigi Gale, Richard Sackler, Peter Lacouture, Mark Chasin: Prolonged anesthesia in joints and body spaces. Euro Celtique, Davidson Davidson & Kappel, March 18, 2003: US06534081 (140 worldwide citation)

Sustained release local anesthetic formulations are administered intra articularly and/or into body spaces/cavities. The formulation is preferably a plurality of injectable microparticles including a local anesthetic and an effective amount of a biocompatible, biodegradable, sustained release materi ...


2
Paul Goldenheim, Peter Lacouture, Donna Donigi Gale, Mark Chasin, Richard Sackler: Prolonged anesthesia in joints and body spaces. Euro Celtique, Davidson Davidson & Kappel, June 19, 2001: US06248345 (100 worldwide citation)

Sustained release local anesthetic formulations are administered intra articularly and/or into body spaces/cavities. The formulation is preferably a plurality of injectable microparticles including a local anesthetic and an effective amount of a biocompatible, biodegradable, sustained release materi ...


3
Paul Goldenheim, Donna Donigi Gale, Kevin Burton, Mohammed Shameem, Amol Ketkar, Mark Chasin, Richard Maskiewicz: Formulations and methods for providing prolonged local anesthesia. Euro Celtique, Davidson Davidson & Kappel, September 17, 2002: US06451335 (68 worldwide citation)

A formulation for inducing sustained regional local anesthesia in a patient comprising a substrate comprising a local anesthetic and an effective amount of a biocompatible, biodegradable, controlled release material prolonging the release of the local anesthetic from the substrate to obtain a revers ...


4
Bruce E Reidenberg, Donna Donigi Gale, Vinayak J Srinivasan: N-but-3-enyl norbuprenorphine and its use as analgesic. Euro Celtique, Darby & Darby, October 24, 2006: US07125884 (6 worldwide citation)

The present invention provides compound having the structure: and pharmaceutically acceptable salts or derivatives thereof, as well as compositions including such compounds. The invention also provides methods of (1) preventing pain, (2) treating pain, (3) inducing sedation, (4) treating opiate addi ...


5
Bruce E Reidenberg, Donna Donigi Gale, Vinayak J Srinivasan: N-but-3-enyl norbuprenorphine and methods of use. Darby & Darby PC, May 6, 2004: US20040087605-A1

The present invention provides compound having the structure: and pharmaceutically acceptable salts or derivatives thereof, as well as compositions including such compounds. The invention also provides methods of (1) preventing pain, (2) treating pain, (3) inducing sedation, (4) treating opiate addi ...


6
Paul Goldenhim, Peter Lacouture, Donna Donigi Gale, Mark Chasin, Richard Sackler: Prolonged anesthesia in joints and body spaces. Davidson Davidson & Kappel, September 18, 2003: US20030175357-A1

Sustained release local anesthetic formulations are administered intra articularly and/or into body spaces/cavities. The formulation is preferably a plurality of injectable microparticles including a local anesthetic and an effective amount of a biocompatible, biodegradable, sustained release materi ...


7
Paul Goldenheim, Peter Lacouture, Donna Donigi Gale, Mark Chasin, Richard Sackler: Prolonged anesthesia in joints and body spaces. Davidson Davidson & Kappel, May 9, 2002: US20020054915-A1

Sustained release local anesthetic formulations are administered intra articularly and/or into body spaces/cavities. The formulation is preferably a plurality of injectable microparticles including a local anesthetic and an effective amount of a biocompatible, biodegradable, sustained release materi ...


8
Donna Donigi Gale, Bruce E Reidenberg, Vinayak J Srinivasan: N-but-E-enyl norbuprenorphine and methods of use. Darby & Darby PC, September 1, 2005: US20050192308-A1

The present invention provides compound having the structure: and pharmaceutically acceptable salts or derivatives thereof, as well as compositions including such compounds. The invention also provides methods of (1) preventing pain, (2) treating pain, (3) inducing sedation, (4) treating opiate addi ...