1
Richard J Melker, Ronald L Hayes, Ka Wang Kevin Wang, Donn Michael Dennis: Application of nanotechnology and sensor technologies for ex-vivo diagnostics. University of Florida Research Foundation, Saliwanchik Lloyd & Saliwanchik, May 30, 2006: US07052854 (43 worldwide citation)

Systems and methods for the ex vivo diagnostic analysis of samples of bodily fluids, including exhaled breath and blood. The present invention uses nanostructure-based assemblies in combination with sensor technology to provide an efficient and accurate means for identifying the presence of a target ...


2
Richard J Melker, Donn Michael Dennis: Application of biosensors for diagnosis and treatment of disease. University of Florida Research Foundation, Saliwanchik Lloyd & Saliwanchik, December 13, 2005: US06974706 (34 worldwide citation)

A method for detecting compounds of interest in bodily fluids, including exhaled breath and blood. The present invention uses biosensors that mimic naturally occurring cellular mechanisms, including RNA oligonucleotide chains or “aptamers,” in combination with molecular beacons or nanotechnology to ...


3
Richard J Melker, Nikolaus Gravenstein, Donn Michael Dennis, Christopher Batich: Handwashing compliance detection system. University of Florida Research Foundation, Thomas Horstemeyer, September 3, 2013: US08525666 (9 worldwide citation)

Systems and methods are provided for monitoring use of handwashing agents to determine compliance with hand hygiene guidelines. A handwashing agent is provided with a detectable, volatile compound, such as odors, which is then rubbed onto a subject's hands using the subject's handwashing technique. ...


4
Anatoly E Martynyuk, Donn Michael Dennis, Alexander V Glushakov, Colin Sumners: Materials and methods for treatment of neurological disorders involving overactivation of glutamatergic ionotropic receptors. University of Florida, Saliwanchik Lloyd & Saliwanchik, September 16, 2003: US06620850 (5 worldwide citation)

The subject invention pertains to methods for treatment of neurological conditions related to, or which can be affected by, modulation of glutamate receptor (GluR) activity. The treatment can be either prophylactic in nature or to alleviate symptoms of such neurological conditions as ischemia, strok ...


5
Anatoly E Martynyuk, Donn Michael Dennis, Alexander V Glushakov, Colin Sumners, M Ian Phillips: Materials and methods for treatment of neurological disorders involving overactivation of glutamatergic ionotropic receptors. Saliwanchik Lloyd & Saliwanchik, A Professional Association, July 29, 2004: US20040147590-A1

The subject invention pertains to pharmaceutical compositions, articles of manufacture, and methods useful for treatment of neurological conditions related to, or which can be affected by, modulation of glutamate receptor (GluR) activity. The treatment can be either prophylactic in nature or to alle ...


6
Anatoly E Martynyuk, Donn Michael Dennis, Alexander V Glushakov, Colin Sumners, M Ian Phillips: Materials and methods for treatment of neurological disorders involving overactivation of glutamatergic ionotropic receptors. Saliwanchik Lloyd & Saliwanchik, A Professional Association, December 30, 2004: US20040266851-A1

The subject invention pertains to pharmaceutical compositions, articles of manufacture, and methods useful for treatment of neurological conditions related to, or which can be affected by, modulation of glutamate receptor (GluR) activity. The treatment can be either prophylactic in nature or to alle ...


7
Richard J Melker, Donn Michael Dennis: Combined nanotechnology and sensor technologies for simultaneous diagnosis and treatment. Saliwanchik Lloyd & Saliwanchik, A Professional Association, February 17, 2005: US20050037374-A1

Systems and methods for diagnosing and/or treating conditions, diseases, or disorders. The present invention uses nanoparticle-based assemblies, which comprise a nanoparticle; a surrogate marker; and a means for detecting a specific chemical entity. Such nanoparticle-based assemblies combine nanotec ...


8
Richard J Melker, Donn Michael Dennis, David G Bjoraker, Mark S Gold: System and method for monitoring health using exhaled breath. Saliwanchik Lloyd & Saliwanchik, A Professional Association, July 19, 2007: US20070167853-A1

The present invention includes systems and methods for monitoring endogenous compound concentration in blood by detecting markers, such as odors, upon exhalation by a patient, wherein such markers are the endogenous compound itself or result from the endogenous compound. In the case of olfactory mar ...


9
Anatoly E Martynyuk, Donn Michael Dennis, Alexander V Glushakov, Colin Sumners, M Ian Phillips: Article of manufacture comprising aromatic amino acids isomers, analogs, or derivatives thereof to treat neurological disorders involving dysfunction of glutamatergic synaptic transmission. Beusse Wolter Sanks Mora & Maire, April 19, 2007: US20070088074-A1

Disclosed herein are articles of manufacture that comprise compositions comprising one or more aromatic amino acids, analogs or isomers thereof, and/or combinations thereof. The articles of manufacture are useful for treatment of neurological conditions related to or which can be affected by, modula ...


10
David G Bjoraker, Richard J Melker, Donn Michael Dennis: Detection and measurement of hematological parameters characterizing cellular blood components. Saliwanchik Lloyd & Saliwanchik, A Professional Association, November 16, 2006: US20060257883-A1

Systems and methods for the diagnostic analysis of blood samples. The present invention uses sensor technology useful in the analysis of headspace sample from blood to provide an efficient and accurate means for identifying the presence of a volatile marker associated with hematological diseases or ...