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Guo Chuangxing, Johnson Mary Catherine, Li Haitao, Marakovits Joseph Timothy, Mcalpine Indrawan James, Dong Liming: Pyrimidine amino pyrazole compounds, potent kinase inhibitors. Pfizer, Guo Chuangxing, Johnson Mary Catherine, Li Haitao, Marakovits Joseph Timothy, Mcalpine Indrawan James, Dong Liming, sFULLER Grover F Jr, March 1, 2007: WO/2007/023382 (14 worldwide citation)

Pyrrole pyrazole compounds of formula I, compositions including these compounds, and methods of their use are provided. Ring A is optionally substituted. The ring formed by Z1, Z2, Z3, Z4 and the two intervening carbons is also optionally substituted. Preferred compounds of formula I have activity a ...


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Bouzida Djamal, Dong Liming, Guo Chuangxing, Hong Yufeng, Li Haitao, Marakovits Joseph Timothy, Yang Anle, Zhang Junhu: Pyrrolopyrazoles, potent kinase inhibitors. Pfizer, Bouzida Djamal, Dong Liming, Guo Chuangxing, Hong Yufeng, Li Haitao, Marakovits Joseph Timothy, Yang Anle, Zhang Junhu, FULLER Grover F Jr, July 13, 2006: WO/2006/072831 (8 worldwide citation)

Pyrrole pyrazole compounds of formula (I), compositions including these compounds and methods of their use are provided. Preferred compounds of formula I have activity as protein kinase inhibitors, including as inhibitors of PAK4.


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Do Quyen Quyen Thuy, Guo Chuangxing, Humphries Paul Stuart, Marakovits Joseph Timothy, Dong Liming, Hou Xinjun, Johnson Mary Catherine: Benzimidazole or indole amides as inhibitors of pin1. Pfizer, Do Quyen Quyen Thuy, Guo Chuangxing, Humphries Paul Stuart, Marakovits Joseph Timothy, Dong Liming, Hou Xinjun, Johnson Mary Catherine, FULLER Grover F Jr, April 20, 2006: WO/2006/040646 (7 worldwide citation)

The invention relates to compounds of the formula (1) and to pharmaceutically acceptable salts and solvates thereof, wherein the variables are defined herein. The invention also relates to methods of treating abnormal cell growth in mammals by administering the compounds of formula (1) and to pharma ...


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Guo Chuangxing, Dagostino Eleanor Ferronyalka, Dong Liming, Hou Xinjun, Margosiak Stephen Anthony: Phosphate/sulfate ester compounds and pharmaceutical compositions for inhibiting protein interacting nima (pin1). Pfizer, Guo Chuangxing, Dagostino Eleanor Ferronyalka, Dong Liming, Hou Xinjun, Margosiak Stephen Anthony, LUMB J Trevor, October 14, 2004: WO/2004/087720 (6 worldwide citation)

Phosphate/sulfate ester compounds that modulate and/or inhibit the activity of protein interacting NIMA (PIN1), and to pharmaceutical compositions containing such compounds are described. The invention is also directed to the therapeutic or prophylactic use of such compounds and compositions, and to ...


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Guo Chuangxing, Augelli Szafran Corinne E, Barta Nancy Sue, Bender Steven Lee, Bigge Christopher Franklin, Caprathe Bradley William, Chatterjee Arindam, Deal Judith, Dong Liming, Fay Lorraine Kathleen, Hou Xinjun, Hudack Raymond Andrew Jr: Heterobicycles fkbp-ligands. Agouron Pharma, June 2, 2004: EP1423119-A1

Diazabicyclo[3.3.1]nonane derivatives that inhibit the peptidyl-prolyl isomerase enzyme activity associated with FK-506 binding proteins (FKBP) are described for treating neurological disorders. Also described are compounds useful for preparing such inhibitors.


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Dong Jixiang, Dong Liming: Medicine for treating pharyngitis and its preparing method. Dong Jixiang, chen datong, January 24, 2007: CN200610018048

The present invention discloses a kind of medicine for treating pharyngitis and its preparation process. The medicine is prepared with nine kinds of Chinese medicinal materials, including detoxificated cantharis, detoxificated red lady-bug, dark plum, menthol, natural indigo, etc. and through prepar ...


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Bai Gang, Yang Yang, Wang Chao, Pan Pengwei, Gao Shengyan, Dong Liming: Composition for treating bronchia asthma. Nankai Univ, houli, August 29, 2007: CN200610014889

The present invention relates to a medicine composition for curing bronchial asthma. Said medicine composition includes glycyrrhetinic acid, glycyrrhizic acid and beta 2 adrenergic receptor excitant. Said medicine composition can be made into compound aerosol, spray, powder aerosol and tablet, etc.