21
Jeffrey J Prior, Donald G Wallace, David H Sierra, Frank A DeLustro: Compositions containing thrombin and microfibrillar nanometer collagen, and methods for preparation and use thereof. Cohesion Technologies, Laurie A Axford, Foley & Lardner, August 1, 2000: US06096309 (100 worldwide citation)

The present invention relates to thrombin-containing hemostatic compositions, their preparation and use. In particular, it relates to hemostatic compositions comprising stabilized thrombin and microfibrillar collagen in an aqueous medium. In a preferred embodiment of the present invention, the compo ...


22
Woonza Rhee, Donald G Wallace, Alan S Michaels, Ramon A Burns Jr, Louis Fries, Frank DeLustro, Hanne Bentz: Implants coated with collagen-polymer conjugates. Collagen Corporation, Morrison & Foerster, August 6, 1996: US05543441 (94 worldwide citation)

Collagen, particularly atelopeptide collagen, exhibits improved handling characteristics when chemically conjugated and/or crosslinked with a synthetic hydrophilic polymer.


23
Woonza Rhee, Donald G Wallace, Alan S Michaels, Ramon A Burns Jr, Louis Fries, Frank DeLustro, Hanne Bentz: Collagen-polymer conjugates. Collagen Corporation, Karl Bozicevic, April 19, 1994: US05304595 (89 worldwide citation)

Collagen, particularly atelopeptide collagen, exhibits improved handling characteristics when chemically conjugated and/or crosslinked with a synthetic hydrophilic polymer.


24
Woonza Rhee, Donald G Wallace, Alan S Michaels, Ramon A Burns Jr, Louis Fries, Frank DeLustro, Hanne Bentz: Composition for bone repair. Collagen Corporation, Karl Bozicevic, November 23, 1993: US05264214 (87 worldwide citation)

Collagen, particularly atelopeptide collagen, exhibits improved handling characteristics when chemically conjugated and/or crosslinked with a synthetic hydrophilic polymer.


25
Woonza Rhee, Donald G Wallace, Alan S Michaels, Ramon A Burns Jr, Louis Fries, Frank DeLustro, Hanne Bentz: Polymer conjugates ophthalmic devices comprising collagen-polymer conjugates. Collagen Corporation, Morrison & Foerster, August 27, 1996: US05550188 (74 worldwide citation)

Pharmaceutically acceptable, non-immunogenic compositions are formed by covalently binding atelopeptide collagen to pharmaceutically pure, synthetic, hydrophilic polymers via specific types of chemical bonds to provide collagen/polymer conjugates. The atelopeptide collagen can be type I, type II or ...


26
Woonza Rhee, Donald G Wallace, Alan S Michaels, Ramon A Burns Jr, Louis Fries, Frank DeLustro, Hanne Bentz: Collagen-polymer conjugates containing an ether linkage. Collagen Corporation, Morrison & Foerster, August 29, 1995: US05446091 (70 worldwide citation)

Pharmaceutically acceptable, non-immunogenic compositions are formed by covalently binding atelopeptide collagen to pharmaceutically pure, synthetic, hydrophilic polymers via specific types of chemical bonds to provide collagen/polymer conjugates. The atelopeptide collagen can be type I, type II or ...


27
Woonza Rhee, Donald G Wallace, Alan S Michaels, Ramon A Burns Jr, Louis Fries, Frank DeLustro, Hanne Bentz: Method of preparing collagen-polymer conjugates. Collagen Corporation, Morrison & Foerster, June 4, 1996: US05523348 (68 worldwide citation)

Collagen, particularly atelopeptide collagen, exhibits improved handling characteristics when chemically conjugated and/or crosslinked with a synthetic hydrophilic polymer.


28
Woonza Rhee, Donald G Wallace, Alan S Michaels, Ramon A Burns Jr, Louis Fries, Frank DeLustro, Hanne Bentz: Method of augmenting tissue using collagen-polymer conjugates. Collagen Corporation, Morrison & Foerster, December 27, 1994: US05376375 (57 worldwide citation)

Collagen, particularly atelopeptide collagen, exhibits improved handling characteristics when chemically conjugated and/or crosslinked with a synthetic hydrophilic polymer.


29
Jeffrey J Prior, Donald G Wallace, David H Sierra, Frank A DeLustro: Compositions containing thrombin and microfibrillar collagen and methods for preparation and use thereof. Cohesion Technologies, Morrison & Foerster, August 28, 2001: US06280727 (47 worldwide citation)

The present invention relates to thrombin-containing hemostatic compositions, their preparation and use. In particular, it relates to hemostatic compositions comprising stabilized thrombin and microfibrillar collagen in an aqueous medium. In a preferred embodiment of the present invention, the compo ...


30
Donald G Wallace, Phillip M Schneider, John L Lundblad: Method of preparing fibronectin and antihemophilic factor. Cutter Laboratories, Theodore J Leitereg, July 27, 1982: US04341764 (31 worldwide citation)

Methods are disclosed for obtaining fibronectin and antihemophilic factor in commercial quantities from blood plasma. In the disclosed methods a blood plasma fraction containing fibronectin and antihemophilic factor is isolated from blood plasma and then solubilized in an aqueous medium. The solutio ...