1
Mark R Prausnitz, Mark G Allen, Sebastien Henry, Devin V McAllister, Donald E Ackley, Thomas Jackson: Devices and methods for enhanced microneedle penetration of biological barriers. Georgia Tech Research Corporation, Ropes & Gray, June 1, 2004: US06743211 (577 worldwide citation)

Microneedle devices and methods of use thereof are provided for the enhanced transport of molecules, including drugs and biological molecules, across tissue by improving the interaction of microneedles and a deformable, elastic biological barrier, such as human skin. The devices and methods act to ( ...


2
Donald E Ackley, Timothy L LeClair, Paul D Swanson: Multicomponent devices for molecular biological analysis and diagnostics. Nanogen, Lyon & Lyon, May 30, 2000: US06068818 (119 worldwide citation)

Methods of manufacture and devices for performing active biological operations utilize various structures to advantageously collect and provide charged biological materials to an array of microlocations. In one embodiment, a device includes focusing electrodes to aid in the direction and transport o ...


3
Donald E Ackley, Michael S Lebby: Optical waveguide apparatus and method for partially collecting light. Motorola, Joe E Barbee, December 8, 1992: US05170448 (108 worldwide citation)

A method is provided for partially collecting light from a polymer waveguide (11, 56). A polymer waveguide (11, 56) is provided, through which a light signal (17) is traveling. A faceted groove (28) is placed in the polymer waveguide (11, 56), thereby reflecting a controllable portion of the light ( ...


4
Chan Long Shieh, Donald E Ackley, George N Maracas, Thomas B Harvey III: Molecular detection apparatus and method using optical waveguide detection. Motorola, Bruce E Stuckman, Jeffrey G Toler, September 23, 1997: US05671303 (83 worldwide citation)

A target molecule at a binding site is detected using an optical waveguide having a surface proximate to the binding site, and a waveguide detector coupled to the optical waveguide. An incident light beam is applied to the binding site along an axis transverse to the surface of the optical waveguide ...


5
Donald E Ackley, Paul D Swanson, Scott O Graham, Elizabeth L Mather, Timothy L LeClair, William F Butler: Advanced active electronic devices for molecular biological analysis and diagnostics. Nanogen, Lyon & Lyon, August 8, 2000: US06099803 (82 worldwide citation)

Methods of manufacture and devices for performing active biological operations utilize various structures to advantageously collect and provide charged biological materials to an array of microlocations. In one embodiment, a device includes focusing electrodes to aid in the direction and transport o ...


6
Donald E Ackley: Microneedle array systems. BioValve Technologies, Fish & Neave IP Group, Ropes & Gray, April 11, 2006: US07027478 (81 worldwide citation)

The present invention relates to systems of microneedle arrays to align and form optical components. Active components such as lasers are combined with optical fibers. Microneedles are fabricated using techniques such as laser drilled Kapton, and combined with optical fiber, using bump bonding and U ...


7
Michael S Lebby, Donald E Ackley: Superluminescent edge emitting device with apparent vertical light emission and method of making. Motorola, Miriam Jackson, March 12, 1996: US05498883 (72 worldwide citation)

A superluminescent edge emitting device is fabricated to have apparent vertical light emission. The superluminescent device is comprised of a semiconductor supporting structure having a major surface. A light emitting portion is formed above a first portion of the major surface, wherein the light em ...


8
Chan Long Shieh, Donald E Ackley: Top emitting VCSEL with etch stop layer. Motorola, Eugene A Parsons, March 8, 1994: US05293392 (68 worldwide citation)

A top emitting vertical cavity surface emitting laser with an etch stop layer positioned in the top mirror stack so the stack can be etched to form a trench surrounding a mesa with the emitting area on the mesa and the trench confining current flow and lasing to the mesa.


9
Donald E Ackley, Chan Long Shieh: VCSEL with separate control of current distribution and optical mode. Motorola, Eugene A Parsons, May 31, 1994: US05317587 (63 worldwide citation)

A VCSEL formed on a substrate with an upper mirror stack etched to form a mesa shaped area with material positioned on the upper mirror stack including optically transparent, electrically conductive material defining an electrical contact window to control current distribution within the laser, and ...


10
Donald E Ackley, Michael Krihak, Chan Long Shieh: Environmental sensor and method therefor. Motorola, Robert F Hightower, February 6, 1996: US05489988 (63 worldwide citation)

A sensor (10,30,40,50,70) for detecting chemicals and changes in the surrounding environment utilizes a sol-gel sensor element (14,16,17,54,56,57) containing a chemical indicator. Grooves (12,13,24,52,53) are formed in a substrate (11,51). The grooves are filled with a sol-gel material having a chem ...