1
Ulrich Speck, Peter Blaszkiewicz, Dieter Seidelmann, Erich Klieger: Novel triiodinated isophthalic acid diamides as nonionic X-ray contrast media. Schering Aktiengesellschaft, Millen & White, December 21, 1982: US04364921 (75 worldwide citation)

New triiodinated isophthalic acid diamides of the formula ##STR1## wherein the amide residues --CO--N.R.sub.1 R.sub.2 and --CO--N.R.sub.3 R.sub.4 are different from each other and


2
Andreas Huth, Dieter Seidelmann, Karl Heinz Thierauch, Guido Bold, Paul William Manley, Pascal Furet, Jeanette Marjorie Wood, Jürgen Mestan, Jose Brüggen, Stefano Ferrari, Martin Krüger, Eckhard Ottow, Andreas Menrad, Michael Schirner: Anthranilic acid amides and the use thereof as medicaments. Schering, Novartis, Millen White Zelano & Branigan P C, October 17, 2006: US07122547 (36 worldwide citation)

The invention relates to anthranilic acid amides and the use thereof as medicaments for the treatment of diseases that are triggered by persistent angiogenesis, in addition to intermediate products in the production of anthranilic acid amides.


3
Claus T Braestrup, Jogen A Christensen, Mogens Engelstoft, Gunter Neef, Ulrich Eder, Ralph Schmiechen, Andreas Huth, Dieter Rahtz, Dieter Seidelmann, Wolfgang Kehr, Dieter Palenschat: Pharmacologically active 3-substituted beta-carbolines. Schering Aktiengesellschaft, Millen & White, March 6, 1984: US04435403 (36 worldwide citation)

3-substituted beta-carbolines of the formula ##STR1## wherein R.sup.C is hydrogen, lower alkyl, alkoxyalkyl of up to 6 C-atoms, cycloalkyl of 3-6 C-atoms, aralkyl of up to 8 C-atoms, or (CH.sub.2).sub.n OR.sup.20


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Karl Heinz Altmann, Guido Bold, Pascal Furet, Paul William Manley, Jeanette Marjorie Wood, Stefano Ferrari, Francesco Hofmann, Jürgen Mestan, Andreas Huth, Martin Krüger, Dieter Seidelmann, Andreas Menrad, Martin Haberey, Karl Heinz Thierauch: VEGF receptor tyrosine kinase inhibitors. Novartis, Schering Aktiengesellschaft, Lydia T McNally, George R Dohmann, April 12, 2005: US06878720 (22 worldwide citation)

Described are compunds of formula (I), wherein W is O or S; X is NR8; Y is CR9R10—(CH2)n wherein R9 and R10 are independently of each other hydrogen or lower alkyl, and n is an integer of from and including 0 to and including 3; or Y is SO2; R1 is aryl; R2 is a bicyclic heteroaryl group comprising o ...


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Andreas Huth, Ralph Schmiechen, Dieter Rahtz, Dieter Seidelmann, Claus T Braestrup: Substituted .beta.-carbolines, and use thereof as medicinal agents. Schering Aktiengesellschaft, Millen & White, November 18, 1986: US04623649 (17 worldwide citation)

Novel substituted .beta.-carboline derivatives of Formula I ##STR1## wherein R.sup.3 is an oxadiazolyl residue of the formula ##STR2## wherein R.sup.5 stands for lower alkyl of up to 3 carbon atoms or an ester ##STR3## with R.sup.6 being hydrogen or lower alkyl of up to 3 carbon atoms, R.sup.4 is hy ...


8
Dieter Rahtz, Andreas Huth, Ralph Schmiechen, Dieter Seidelmann, Wolfgang Kehr, Herbert H Schneider, Claus T Braestrup: Substituted 5H-pyrimido[5,4-b]indoles. Schering Aktiengesellschaft, Millen & White, January 14, 1986: US04564610 (17 worldwide citation)

Substituted 5H-pyrimido[5,4-b]indoles of Formula I ##STR1## wherein R.sup.2 is halogen; the oxadiazolyl group ##STR2## wherein R" is lower alkyl with up to 3 carbon atoms; C.sub.1-5 -alkyl, cycloalkyl, aralkyl, or aryl; OR.sup.I, SO.sub.n R.sup.I with n being 0, 1, or 2, or ##STR3## wherein R.sup.I ...


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Andreas Huth, Dieter Seidelmann, Dieter Rahtz, Ralph Schmiechen, Herbert Schneider, Lechoslaw Turski: .beta.-carboline derivatives for use as pharmaceutical agents. Schering Aktiengesellschaft, Millen White Zelano & Branigan, April 9, 1996: US05506234 (11 worldwide citation)

.beta.-carbolines of formula I are described ##STR1## in which R.sup.A is a C.sub.6-12 aryl hetaryl as defined herein, that can be substituted singly to multiply with halogen, C.sub.1-4 -alkoxy, C.sub.1-4 -alkyl or amino,