1
Dennis M Treu, Jeffrey H Burbank, James M Brugger: Flow-through peritoneal dialysis systems and methods with on-line dialysis solution regeneration. NxStage Medical, Ryan Kromholz & Manion S C, July 3, 2001: US06254567 (251 worldwide citation)

Peritoneal dialysis is performed by circulating peritoneal dialysis solution through a peritoneal cavity by conveying peritoneal dialysis solution through an inlet branch into the peritoneal cavity and by withdrawing peritoneal dialysis solution through an outlet branch from the peritoneal cavity. P ...


2
Rodney S Kenley, Dennis M Treu, Frederick H Peter Jr, Thomas M Feldsein, Kenneth E Pawlak, Wayne F Adolf, Linda Roettger: Hot water disinfection of dialysis machines, including the extracorporeal circuit thereof. Aksys, Banner & Witcoff, January 7, 1997: US05591344 (221 worldwide citation)

A dialysis machine is disclosed that incorporates a water treatment module, a dialysate preparation module having a dialysate circuit, and an extracorporeal circuit including a dialyzer and arterial and venous blood lines that connect to the patient. The machine accomplishes on-line disinfection of ...


3
Jeffrey H Burbank, James M Brugger, Dennis M Treu: Fluid processing systems and methods using extracorporeal fluid flow panels oriented within a cartridge. NxStage Medical, Proskauer Rose, June 17, 2003: US06579253 (165 worldwide citation)

A first flow path is defined within a first panel that forms a part of an extracorporeal fluid circuit. A second flow path is defined within a second panel that also forms a part of the extracorporeal fluid circuit. The first and second panels are oriented in a fluid processing cartridge for mountin ...


4
Jeffrey H Burbank, James M Brugger, Dennis M Treu: Fluid processing systems and methods using extracorporeal fluid flow panels oriented within a cartridge. NxStage Medical, Proskauer Rose, February 8, 2005: US06852090 (144 worldwide citation)

A first flow path is defined within a first panel that forms a part of an extracorporeal fluid circuit. A second flow path is defined within a second panel that also forms a part of the extracorporeal fluid circuit. The first and second panels are oriented in a fluid processing cartridge for mountin ...


5
James M Brugger, Jeffrey H Burbank, Dennis M Treu: Method and apparatus for leak detection in a fluid line. NxStage Medical, Proskauer Rose, June 3, 2003: US06572576 (142 worldwide citation)

One of the most significant safety concerns in the automation of extracorporeal blood treatments such as dialysis is the risk of blood leakage. Such systems draw blood at such a high rate that a loss of integrity in the blood circuit can be catastrophic. The most reliable leak detection method known ...


6
Rodney S Kenley, Dawn Matthews, Dennis M Treu, Frederick H Peter Jr, Thomas M Feldsein: Method of rinsing back blood to hemodialysis patient. Aksys, McDonnell Boehnen Hulbert & Berghoff, November 25, 1997: US05690831 (141 worldwide citation)

A method is described herein for automatically rinsing blood back to a patient. The method comprises the steps of pumping dialysate (or, alternatively, saline solution) through a dialyzer into an extracorporeal circuit, and pumping blood in the extracorporeal circuit out the arterial and venous line ...


7
Rodney S Kenley, Dennis M Treu, Tom L Brose, Thomas M Feldsein, Kenneth E Pawlak: Methods for ultrafiltration control in hemodialysis. AKSYS, McDonnell Boehnen Hulbert & Berghoff, March 10, 1998: US05725776 (128 worldwide citation)

Methods and apparatus for increasing the accuracy of ultrafiltration in a dialysis machine and decreasing the time required for dialysis. The machine inclused a substantially non-compliant tank for mixing and storing a batch of dialsyate. In a preferred form, the tank is a hollow vessel made from a ...


8
Jeffrey H Burbank, Dennis M Treu, Barry N Fulkerson, Steven A White: Interactive systems and methods for supporting hemofiltration therapies. NxStage Medical, Proskauer Rose, January 6, 2004: US06673314 (126 worldwide citation)

A hemofiltration machine at a local treatment site is linked to a remote main data base server by a local transmitting/receiving device. The machine acts as a satellite of the main data base server. The machine performs specified therapy tasks while monitoring basic safety functions and providing th ...


9
Jeffrey H Burbank, James M Brugger, Dennis M Treu: Measurement of fluid pressure in a blood treatment device. Nxstage Medical, Proskauer Rose, December 12, 2006: US07147613 (122 worldwide citation)

A first flow path is defined within a first panel that forms a part of an extracorporeal fluid circuit. A second flow path is defined within a second panel that also forms a part of the extracorporeal fluid circuit. The first and second panels are oriented in a fluid processing cartridge for mountin ...


10
James M Brugger, Jeffrey H Burbank, Dennis M Treu: Method for performing renal replacement therapy including producing sterile replacement fluid in a renal replacement therapy unit. NxStage Medical, Proskauer Rose, November 18, 2003: US06649063 (114 worldwide citation)

A method and device for renal replacement therapy is described that sterile-filters solution that can subsequently be used as a replacement fluid in the same unit. The devices and methods include a pump that can be reversed from its normal forward-pumping direction to sterilize a container of replac ...