21
Michael A Evans, Denise Demarais, Alexander Khairkhahan, Dino Decicco: Apparatus and method for removing occlusive material within blood vessels. Bacchus Vascular, Townsend and Townsend and Crew, July 15, 2008: US07399307 (59 worldwide citation)

An apparatus for treating an occlusive region of a blood vessel includes a catheter including a first lumen extending from an end port to a first side port, and a second lumen extending from a proximal end of the catheter to a second side port. A balloon is mounted on the catheter between the first ...


22
Michael Evans, Denise Demarais, Gwendolyn Watanabe, Stephen Leeflang: Devices for percutaneous remote endarterectomy. Bacchus Vascular, Townsend and Townsend and Crew, April 14, 2009: US07517352 (57 worldwide citation)

The present invention provides devices, systems, methods and kits for the percutaneous removal of unwanted tissue or obstructive matter from body cavities or lumens, particularly from the vasculature. Blood vessels, including the coronary, peripheral and neurovascular circulation, which are narrowed ...


23
Denise Demarais, Nicolas Zadno, Benjamin J Clark, Erik Thai, Howard R Levin, Mark Gelfand: Ultrasound apparatuses for thermally-induced renal neuromodulation. Medtronic Ardian Luxembourg r l, September 30, 2014: US08845629 (19 worldwide citation)

Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or ...


24
Michael A Evans, Denise Demarais, Dino De Cicco, Kelvin Ning, Alexander Khairkhahan, Tyler Jon Strang: Apparatus and methods for clot dissolution. Bacchus Vascular, Townsend and Townsend and Crew, July 27, 2010: US07763010 (18 worldwide citation)

Clot disruption and dissolution are achieved using a catheter having the ability to infuse a thrombolytic agent, aspirate clot and fluid, and allow passage of a guidewire. Optionally, the catheter may also include a mechanical agitator for further disrupt clot in the presence of the thrombolytic age ...


25
Denise Demarais, Nicolas Zadno, Benjamin J Clark, Erik Thai, Howard R Levin, Mark Gelfand: Methods for inhibiting renal nerve activity. Medtronic Ardian Luxembourg r l, April 1, 2014: US08684998 (16 worldwide citation)

Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or ...


26
Denise Demarais: Methods for multi-vessel renal neuromodulation. Ardian, Perkins Coie, April 30, 2013: US08433423 (16 worldwide citation)

Methods and apparatus are provided for multi-vessel neuromodulation, e.g., via a pulsed electric field. Such multi-vessel neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation ...


27
Mark Deem, Hanson Gifford III, Denise Demarais, Douglas Sutton, Erik Thai, Mark Gelfand, Howard R Levin: Apparatuses for renal neuromodulation and associated systems and methods. Medtronic Ardian Luxembourg r l, October 1, 2013: US08548600 (9 worldwide citation)

Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the ...


28
David W Snow, Joseph Karratt, Jeffry J Grainger, Denise Demarais: Devices and methods for controlling expandable prostheses during deployment. J W Medical Systems, Kilpatrick Townsend & Stockton, March 24, 2015: US08986362 (9 worldwide citation)

Prosthesis delivery devices and methods are provided that enable precise control of prosthesis position during deployment. The prosthesis delivery devices may carry multiple prostheses and include deployment mechanisms for delivery of a selectable number of prostheses. Control mechanisms are provide ...


29
Denise Demarais, Hanson Gifford III: Methods for thermal modulation of nerves contributing to renal function. Medtronic Ardian Luxembourg r l, December 31, 2013: US08620423 (9 worldwide citation)

Methods and apparatus are provided for treatment of heart arrhythmia via renal neuromodulation. Such neuromodulation may effectuate irreversible electroporation or electrofusion, ablation, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockad ...


30
Denise Demarais, Hanson Gifford III, Mark Deem, Nicolas Zadno, Benjamin J Clark, Andrew Wu, Kenneth J Michlitsch: Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen. Medtronic Ardian Luxembourg r l, May 21, 2013: US08444640 (8 worldwide citation)

Methods and apparatus are provided for non-continuous circumferential treatment of a body lumen. Apparatus may be positioned within a body lumen of a patient and may deliver energy at a first lengthwise and angular position to create a less-than-full circumferential treatment zone at the first posit ...