1
Milton E Fuller, David W Deamer, Mark N Iverson, Ajit J Koshy deceased: Radio frequency spectral analysis for in-vitro or in-vivo environments. Solid State Farms, Flehr Hohbach Test Albritton & Herbert, August 11, 1998: US05792668 (212 worldwide citation)

Concentration of a target chemical in the presence of other substances in a specimen is determined by subjecting the specimen to radio frequency electromagnetic components, sequentially or otherwise, ranging to about 5 GHz. The reflected and/or transmitted signal real and imaginary components at the ...


2
George Church, David W Deamer, Daniel Branton, Richard Baldarelli, John Kasianowicz: Characterization of individual polymer molecules based on monomer-interface interactions. President & Fellows of Harvard College, The Regents of the University of California, Fish & Richardson P C, August 18, 1998: US05795782 (206 worldwide citation)

A method is disclosed for characterizing a linear polymer molecule by measuring physical changes across an interface between two pools of media as the linear polymer traverses the interface and monomers of the polymer interact with the interface, where the physical changes are suitable to identify c ...


3
Richard Baldarelli, Daniel Branton, George Church, David W Deamer, Mark Akeson, John Kasianowicz: Characterization of individual polymer molecules based on monomer-interface interactions. The United States of America represented by the Secretary of Commerce, The Regents of the University of California, Fish & Richardson P C, January 18, 2000: US06015714 (173 worldwide citation)

A method for sequencing a nucleic acid polymer by (1) providing two separate, adjacent pools of a medium and an interface between the two pools, the interface having a channel so dimensioned as to allow sequential monomer-by-monomer passage from one pool to the other pool of only one nucleic acid po ...


4
David W Deamer: Method for encapsulating materials into liposomes. The Regents of the University of California, Majestic Gallagher Parsons & Siebert, May 7, 1985: US04515736 (148 worldwide citation)

A novel encapsulation method is provided in which liposome dispersions are dried in the presence of a material to be encapsulated. As drying occurs, the individual liposomes fuse to form multilamellar structures which capture the material between lipid lamellae. Upon rehydration, lipid vesicles form ...


5
Mark Akeson, Daniel Branton, David W Deamer, Jeffrey R Sampson: Methods and apparatus for characterizing polynucleotides. President and Fellows of Harvard College, Regents of the University of California, Agilent Technologies, Clark & Elbing, Kristina Bieker Brady, July 3, 2007: US07238485 (86 worldwide citation)

Systems and methods for analysis of polymers, e.g., polynucleotides, are provided. The systems are capable of analyzing a polymer at a specified rate. One such analysis system includes a structure having a nanopore aperture and a molecular motor, e.g., a polymerase, adjacent the nanopore aperture.


6
Mark Akeson, Daniel Branton, George Church, David W Deamer: Characterization of individual polymer molecules based on monomer-interface interactions. President and Fellows of Harvard College, Regents of the University of California, Clark & Elbing, Kristina Bieker Brady, March 13, 2007: US07189503 (83 worldwide citation)

The invention relates to a method for detecting a double-stranded region in a nucleic acid by (1) providing two separate, adjacent pools of a medium and a interface between the two pools, the interface having a channel so dimensioned as to allow sequential monomer-by-monomer passage of a single-stra ...


7
Mark A Akeson, David W Deamer, Daniel Branton: Miniature support for thin films containing single channels or nanopores and methods for using same. The Regents of the University of California, Bret E Field, Bozicevic Field & Francis, July 31, 2001: US06267872 (76 worldwide citation)

Single-channel thin film devices and methods for using the same are provided. The subject devices comprise cis and trans chambers connected by an electrical communication means. At the cis end of the electrical communication means is a horizontal conical aperture sealed with a thin film that include ...


8
Mark A Akeson, David W Deamer, Daniel Branton: Miniature support for thin films containing single channels or nanopores and methods for using the same. The Regents of the University of California, President and Fellows of Harvard College, Bret E Field, Bozicevic Field & Francis, June 8, 2004: US06746594 (76 worldwide citation)

Single-channel thin film devices and methods for using the same are provided. The subject devices comprise cis and trans chambers connected by an electrical communication means. At the cis end of the electrical communication means is a horizontal conical aperture sealed with a thin film that include ...


9
David W Deamer: Methods of determining the presence of double stranded nucleic acids in a sample. The Regents of the University of California, Bret E Field, Bozicevic Field & Francis, August 6, 2002: US06428959 (71 worldwide citation)

Methods for determining the presence of double stranded nucleic acids in a sample are provided. In the subject methods, nucleic acids present in a fluid sample are translocated through a nanopore, e.g. by application of an electric field to the fluid sample. The current amplitude through the nanopor ...


10
David W Deamer: Methods of determining the presence of double stranded nucleic acids in a sample. The Regents of the University of California, Brett E Field, Bozicevic Field & Francis, September 9, 2003: US06617113 (42 worldwide citation)

Methods for determining the presence of double stranded nucleic acids in a sample are provided. In the subject methods, nucleic acids present in a fluid sample are translocated through a nanopore, e.g. by application of an electric field to the fluid sample. The current amplitude through the nanopor ...