1
David J Vachon, Brooks B Cochran, Bill C Ponder: Hydrophilic polymeric material for coating biosensors. MiniMed, Gates & Cooper, November 4, 2003: US06642015 (322 worldwide citation)

Disclosed is a biocompatible membrane comprising a hydrophilic polyurea composition. The hydrophilic polyurea composition comprises the product of a reaction mixture comprising (a) an amino terminated polysiloxane, (b) a hydrophilic polymer selected from the group consisting of a diamino terminated ...


2
David J Vachon: Anti-inflammatory biosensor for reduced biofouling and enhanced sensor performance. Medtronic MiniMed, Gates & Cooper, December 26, 2006: US07153265 (265 worldwide citation)

A biosensor including an external surface, and an accessory material in close proximity to the external surface. The accessory material includes a coating containing a hydrophilic material and/or a fiber modified to deliver a therapeutic agent. The biosensor modifies a biological response to the bio ...


3
David J Vachon, Jenn Hann Wang: Microelectrogravimetrically plated biosensors and apparatus for producing same. MiniMed, Gates & Cooper, November 2, 2004: US06811659 (252 worldwide citation)

Disclosed is a method for microelectrogravimetrically depositing an electroactive species onto an electrode or a plurality of electrodes comprising dispensing a solution containing the electroactive species from a microdispenser to form a hanging drop of the solution and contacting the electrode wit ...


4
Joseph C Walsh, Aaron M Heiss, Glenn Noronha, David J Vachon, Stephen M Lane, Joe H Satcher Jr, Thomas A Peyser, William Peter Van Antwerp, John Joseph Mastrototaro: Long wave fluorophore sensor compounds and other fluorescent sensor compounds in polymers. Medtronic MiniMed, The Regents of the University of California, Gates & Cooper, July 20, 2004: US06766183 (213 worldwide citation)

Fluorescent biosensor molecules, fluorescent biosensors and systems, as well as methods of making and using these biosensor molecules and systems are described. Embodiments of these biosensor molecules exhibit fluorescence emission at wavelengths greater than about 650 nm. Typical biosensor molecule ...


5
Glenn Noronha, Jonathan Reilly, Joseph C Walsh, Brooks Cochran, Aaron M Heiss, Bill C Ponder, David J Vachon: Polymers functionalized with fluorescent boronate motifs and methods for making them. Medtronic MiniMed, Gates & Cooper, August 9, 2005: US06927246 (154 worldwide citation)

Improved polymer matrices which incorporate fluorescent biosensor molecules as well as methods of making and using these polymer matrices are described. Such matrices can be used in fluorescent biosensors and biosensor systems, including those which are used in the detection of polyhydroxylated anal ...


6
Aaron M Heiss, Joseph C Walsh, David J Vachon, Glenn Noronha, Jonathan Reilly, Bill C Ponder, William P Van Antwerp: Analyte sensing via acridine-based boronate biosensors. Medtronic MiniMed, Gates & Cooper, May 16, 2006: US07045361 (142 worldwide citation)

Fluorescent biosensor molecules, fluorescent biosensors and systems, as well as methods of making and using these biosensor molecules and systems are described. These biosensor molecules address the problem of obtaining fluorescence emission at wavelengths greater than about 500 nm. Biosensor molecu ...


7
David J Vachon: Implantable stimulation lead having an advanceable therapeutic drug delivery system. Pacesetter, Malcolm J Romano, Harold C Schloss, July 2, 1996: US05531780 (141 worldwide citation)

A pacing lead having a stylet introduced anti-inflammatory drug delivery element advanceable from the distal tip electrode. The element is preferably formed as a moldable biocompatible composite material. The element has a biocompatible matrix material which may be combined with drugs and therapeuti ...


8
David J Vachon, Jenn Hann Wang: Microelectrogravimetric method for plating a biosensor. MiniMed, Gates & Cooper, January 22, 2002: US06340421 (138 worldwide citation)

Disclosed is a method for microelectrogravimetrically depositing an electroactive species onto an electrode or a plurality of electrodes comprising dispensing a solution containing the electroactive species from a microdispenser to form a hanging drop of the solution and contacting the electrode wit ...


9
David J Vachon, Shahram Moaddeb: Implantable stimulation lead having an advanceable therapeutic drug delivery system. Pacesetter, Malcolm J Romano, September 5, 1995: US05447533 (127 worldwide citation)

A pacing lead having a stylet introduced anti-inflammatory drug delivery element advanceable from the distal tip electrode. The element is preferably formed as a moldable biocompatible composite material. The element has a biocompatible matrix material which may be combined with drugs and therapeuti ...


10
David J Vachon, Shahram Moaddeb: Implantable stimulation lead having an advanceable therapeutic drug delivery system. Pacesetter, November 10, 1998: US05833715 (127 worldwide citation)

A pacing lead having a stylet introduced anti-inflammatory drug delivery element advanceable from the distal tip electrode. The element is preferably formed as a moldable biocompatible composite material. The element has a biocompatible matrix material which may be combined with drugs and therapeuti ...



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