1
Juan Mantelle, David Houze, David Kanios: Bioadhesive compositions and methods for topical administration of active agents. Noven Pharmaceuticals, Foley & Lardner, May 13, 2003: US06562363 (179 worldwide citation)

Bioadhesive compositions in a flexible, finite form for topical application to skin or mucous membranes comprising a composition which results from an admixture of at least one PVP polymer, at least one bioadhesive, optionally a pharmaceutically acceptable solvent suitable for use with an active age ...


2
Juan Mantelle, David Houze: Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures. Noven Pharmaceuticals, Foley & Lardner, November 13, 2001: US06316022 (64 worldwide citation)

A transdermal composition is disclosed which contains a blend of one or more polymers, one or more drugs, at least one of which has a low molecular weight and is liquid at or about room temperatures. The composition is substantially free of water and liquids which have a normal boiling point (a) opt ...


3
Sylvia Rossi Montero, Juan Mantelle, David Kanios, David Houze: Solubility enhancement of drugs in transdermal drug delivery systems and methods of use. Noven Pharmaceuticals, Jay G Kolman, October 15, 2002: US06465004 (43 worldwide citation)

A composition and method for the continuous and controlled transdermal delivery of an active agent comprising a pharmaceutically acceptable active agent carrier and cellulose derivative which provides a solubilizing and stabilizing effect on the active agents incorporated therein.


4
David Houze, Viet Nguyen: Enhanced drug delivery in transdermal systems. Noven Pharmaceuticals, Foley & Lardner, November 25, 2008: US07456159 (22 worldwide citation)

A composition for transdermal administration resulting from an admixture includes: a therapeutically effective amount of a drug that includes a parent drug and a prodrug; and and a pharmaceutically acceptable carrier, wherein the parent drug and prodrug are individually present in an amount sufficie ...


5
David Kanios, Juan A Mantelle, David Houze: Barrier film lined backing layer composition and method for topical administration of active agents. Noven Pharmaceuticals, Jay G Kolman Esq, Scott M Oldham Esq, June 20, 2006: US07063859 (16 worldwide citation)

A transdermal drug delivery device for topical application of active agents is disclosed. The invention comprises the use of a flexible and soft backing layer, in particular a cellular foam, having an inner surface and an outer surface, wherein an impermeable polymeric barrier film is affixed to its ...


6
Juan Mantelle, David Houze: Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures. Noven Pharmaceuticals, Foley & Lardner, August 9, 2011: US07993671 (9 worldwide citation)

A transdermal composition is disclosed which contains a blend of one or more polymers, one or more drugs, at least one of which has a low molecular weight and is liquid at or about room temperatures. The composition is substantially free of water and liquids which have a normal boiling point (a) opt ...


7
David Houze: Enhanced drug delivery in transdermal systems. Noven Pharmaceuticals, Foley & Lardner, January 11, 2011: US07867986 (7 worldwide citation)

A composition for transdermal administration resulting from an admixture includes: a therapeutically effective amount of a pharmaceutically active agent that includes a corresponding steroid and a steroid derivative; and a carrier for the pharmaceutically active agent. The steroid and the correspond ...


8
David Houze: Enhanced drug delivery in transdermal systems. Noven Pharmaceuticals, Foley & Lardner, February 1, 2011: US07879831 (5 worldwide citation)

A composition for transdermal administration resulting from an admixture includes: a therapeutically effective amount of a pharmaceutically active agent that includes a corresponding steroid and a steroid derivative; and a carrier for the pharmaceutically active agent. The steroid and the correspond ...


9
David Houze: Enhanced drug delivery in transdermal systems. Noven Pharamaceticals, Foley & Lardner, December 7, 2010: US07846916 (5 worldwide citation)

A composition for transdermal administration resulting from an admixture includes: a therapeutically effective amount of a pharmaceutically active agent that includes a corresponding steroid and a steroid derivative; and a carrier for the pharmaceutically active agent. The steroid and the correspond ...


10
Rod Hartwig, David Houze: Transdermal delivery of ketoprofen polar derivatives. Noven Pharmaceuticals, Foley & Lardner, August 2, 2011: US07989496 (5 worldwide citation)

A topical or transdermal composition including a polar derivative of ketoprofen and a pharmaceutically acceptable topical or transdermal carrier, wherein the polar derivative of ketoprofen comprises a polarity that is greater than that of ketoprofen.