1
Yun He, Tao Jiang, Kelli L Kuhen, David Archer Ellis, Baogen Wu, Tom Yao Hsiang Wu, Badry Bursulaya: Oxindoles with anti-HIV activity. IRM, Emily Tongro Wu, Genomics Institute of the Novartis Research Foundation, April 17, 2007: US07205328 (9 worldwide citation)

The present invention relates to inhibition of viruses, e.g., HIV using oxindoles and compounds related to oxindoles. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophyl ...


2
Hong Liu, Xiaohui He, Ha Soon Choi, Kunyong Yang, David Woodmansee, Zhicheng Wang, David Archer Ellis, Baogen Wu, Yun He, Truc Ngoc Nguyen: Compounds and compositions as inhibitors of cannabinoid receptor 1 activity. IRM, Chihang Amy Smith, Genomics Institute of the Novartis Research Foundation, April 17, 2012: US08158634

The invention provides compounds having Formula Ia, or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4 and Y are as defined in the specification; as well as pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or di ...


3
Baogen Wu, Yun He, Truc Ngoc Nguyen, Kelli L Kuhen, David Archer Ellis, Tao Jiang, Xiaohui He, Kunyong Yang, Badry Bursulaya: Pyrrolidones with anti-HIV activity. IRM, Emily Tongo Wu, Genomics Institute of the Novartis Research Foundation, February 24, 2009: US07495016

The present invention relates to inhibition of viruses, e.g., HIV using pyrrolidones and compounds related to pyrrolidones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of p ...


4
Xiaohui He, Kunyong Yang, Hong Liu, David Archer Ellis: Azolopyrimidines as inhibitors of cannabinoid 1 activity. IRM, Chihang Amy Smith, Genomics Institute of the Novartis Research Foundation, May 13, 2014: US08722691

The invention provides compounds, pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB1). The compounds are of the Formulae Ia, Ic, Ig and Ik:


5
Baogen Wu, Yun He, Truc Ngoc Nguyen, Kelli L Kuhen, David Archer Ellis, Tao Jiang, Xiaohui He, Kunyong Yang, Badry Bursulaya: Pyrrolidones with anti-HIV activity. IRM, Emily Tongco Wu, Genomics Institute of the Novartis Research Foundation, October 13, 2009: US07601742

The present invention relates to inhibition of viruses, e.g., HIV using pyrrolidones and compounds related to pyrrolidones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of p ...


6
Valentina Molteni, Xiaolin Li, Juliet Nabakka, David Archer Ellis, Beth Anaclerio, Enrique Saez, John Wityak: Compounds and compositions as LXR modulators. Daniel E Raymond, Genomiccs Institute of the Novartis Research Foundation, October 29, 2013: US08569345

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of liver X receptors (LXRs).


7
Valentina Molteni, Xiaolin Li, Juliet Nabakka, David Archer Ellis, Beth Anaclerio, Enrique Saez, John Wityak: Compounds and compositions as LXR modulators. Hamilton, Daniel E Raymond, Genomics Institute of the Novartis Research Foundation, April 17, 2012: US08158662

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of liver X receptors (LXRs).


8
Yun He, David Archer Ellis, Beth Marie Anaclerio, Kelli L Kuhen, Baogen Wu, Tao Jiang: Quinolones with anti-HIV activity. IRM, Morgan Lewis & Bockius, March 28, 2006: US07019141

The present invention relates to inhibition of viruses, e.g., HIV using quinolones and compounds related to quinolones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of proph ...


9
David Archer Ellis, Lukas Scheibler, Najam A Sharif: Prostaglandin conjugates and derivatives for treating glaucoma and ocular hypertension. Novartis, Mark Flanigan, March 28, 2017: US09604949

Prostaglandin conjugates and derivatives and methods for their use to treat glaucoma and/or lower intraocular pressure are disclosed. Additionally, ophthalmic pharmaceutical compositions useful in the treatment of eye diseases such as glaucoma and elevated intraocular pressure are disclosed. Such co ...


10
Baogen Wu, Yun He, Truc Ngyuen, Kelli L Kuhen, David Archer Ellis, Tao Jiang, Xiaohui Xe, Kunyong Yang, Badry Bursulaya: Pyrrolidones with anti-HIV activity. IRM a Delaware, Townsend And Townsend And Crew, August 12, 2004: US20040157859-A1

The present invention relates to inhibition of viruses, e.g., HIV using pyrrolidones and compounds related to pyrrolidones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of p ...