1
Lawrence J Mulligan, D Curtis Deno, Tom D Bennett, David A Igel, Michael R S Hill: Implantable medical device for monitoring congestive heart failure. Medtronic, Girma Wolde Michael, August 20, 2002: US06438408 (228 worldwide citation)

An implantable stimulator and monitor measures a group of heart failure parameters indicative of the state of heart failure employing EGM signals, measures of blood pressure including absolute pressure P, developed pressure (DP=systolic P−diastolic P), and/or dP/dt, and measures of heart cham ...


2
D Curtis Deno, Lawrence J Mulligan, Tom D Bennett, David A Igel, Michael R S Hill, Richard J Shaw: Implantable medical device for treating cardiac mechanical dysfunction by electrical stimulation. Medtronic, Michael C Soldner, Paul H McDowall, Girma Wolde Michael, May 18, 2004: US06738667 (119 worldwide citation)

An implantable stimulator and monitor measures a group of heart failure parameters indicative of the state of heart failure employing EGM signals, measures of blood pressure including absolute pressure P, developed pressure (DP=systolic P−diastolic P), and/or dP/dt, and measures of heart cham ...


3
David A Igel, Bruce L Wilkoff: Non-programmable automated heart rhythm classifier. The Cleveland Clinic Foundation, Calfee Halter & Griswold, February 20, 2001: US06192273 (98 worldwide citation)

A nonprogrammable automated heart rhythm classifier that may be used alone or in conjunction with a therapy system for delivering shock treatment or therapeutic drugs to a patient, a monitoring or recording system, a paging or alarm system, or other rhythm classifying device. The nonprogrammable hea ...


4
David A Igel, H Toby Markowitz, Robert A Betzold, Karen J Kleckner, Jeremy A Schroetter: Regularization of ventricular rate during atrial tachyarrhythmia. Medtronic, Girma Wolde Michael, August 13, 2002: US06434424 (96 worldwide citation)

A pacing system provided with a mode switching feature and ventricular rate regularization (VRR) function adapted to stabilize or regularize ventricular heart rate during chronic or paroxysmal atrial tachyarrhythmia. In a preferred embodiment, the pacing system nominally operates in an atrial synchr ...


5
D Curtis Deno, David E Euler, Lawrence J Mulligan, Edwin G Duffin, David A Igel: Cardiac stimulation during a refractory period. Medtronic, Paul H McDowall, Girma Wolde Michael, November 6, 2007: US07292888 (15 worldwide citation)

A medical device, e.g., an implantable medical device, delivers one or more neurally-excitable stimulation pulses to myocardial tissue during a period when the tissue is refractory. The width of the pulses is less than or equal to approximately one half millisecond. In some embodiments, the current ...


6
John E Burnes, David A Igel, John C Rueter, Yong K Cho, Luc R Mongeon, Harold E Stone, Jodi Zilinski: Algorithm for the automatic determination of optimal pacing intervals. Medtronic, Stephen W Bauer, May 4, 2010: US07711423 (11 worldwide citation)

Impedance, e.g. sub-threshold impedance, is measured across the heart at selected cardiac cycle times as a measure of chamber expansion or contraction. One embodiment measures impedance over a long AV interval to obtain the minimum impedance, indicative of maximum ventricular expansion, in order to ...


7
Tommy D Bennett, Mark Choi, David A Igel, Michael R S Hill, Teresa A Whitman, Douglas A Hettrick: System and method for detecting cardiovascular health conditions using hemodynamic pressure waveforms. Medtronic, Paul H McDowall, Steve Bauer, May 6, 2008: US07367951 (10 worldwide citation)

A cardiovascular analysis system and method includes an implantable medical device with a sensor positioned to sense a hemodynamic pressure over time. The implantable medical device generates hemodynamic pressure waveform data based upon the hemodynamic pressure sensed. A processor analyzes the hemo ...


8
Tommy D Bennett, Mark Choi, David A Igel, Michael R S Hill, Teresa A Whitman: System and method for detecting artifactual hemodynamic waveform data. Medtronic, Stephen W Bauer, May 4, 2010: US07708693 (2 worldwide citation)

A system and method for cardiovascular analysis includes an implantable medical device capable of generating hemodynamic pressure waveform data based upon sensed pressure. Hemodynamic waveform data is analyzed to identify artifactual data represented in the hemodynamic waveform.


9
Karen J Kleckner, Kathleen A Prieve, Jeffrey M Gillberg, Ren Zhou, Kenneth M Anderson, D Curtis Deno, Glenn C Zillmer, Ruth N Klepfer, Vincent E Splett, David E Euler, Lawrence J Mulligan, Edwin G Duffin, David A Igel, John E Burnes: Secure and efficacious therapy delivery for a pacing engine. Medtronic, Carol F Barry, August 11, 2015: US09101772

A method of stimulation therapy and an apparatus for providing the therapy which addresses cardiac dysfunction including heart failure. The therapy employs atrial pacing pulses delivered to a heart after the atrial refractory period and timed so that they will not cause a ventricular contraction. Th ...


10
D Curtis Deno, David E Euler, Lawrence J Mulligan, Edwin G Duffin, David A Igel: Electrically efficient neurally-excitable stimulation technical field. Medtronic, February 17, 2005: US20050038479-A1

A medical device, e.g., an implantable medical device, delivers one or more neurally-excitable stimulation pulses to myocardial tissue during a period when the tissue is refractory. The width of the pulses is less than or equal to approximately one half millisecond. In some embodiments, the current ...



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