1
Heinrichs David E, Dale Suzanne: Pharmaceutical compositions comprising inhibitors of iron transport, and method of identifying iron transport inhibitors, fn staphylococcus aureus. The University Of Western Ontario, Heinrichs David E, Dale Suzanne, SCHUMACHER Lynn C, March 2, 2006: WO/2006/021893 (8 worldwide citation)

Pharmaceutical compositions comprising inhibitors of the SirABC or FhuC iron-siderophore transport system, and their use for treating an infection of Staphylococcus aureus in a subject Screening methods for mdentifymg SirABC or FhuC iron-siderophore transport system inhibitors are also disclosed


2
Heinrichs David E, Dale Suzanne: Screening assays for inhibitors of a staphylococcus aureus siderophore. The University Of Western Ontario, Heinrichs David E, Dale Suzanne, SCHUMACHER Lynn C, April 27, 2006: WO/2006/043182 (1 worldwide citation)

Isolation of an iron regulated, nme-gene operon (designated sbn) from Staphylococcus aureus (RN6390), responsible for the biosynthesis of staphylobactm, a novel S. aureus siderophore Methods for treating or preventing a disease or condition caused by S. aureus infection, as well as methods for ident ...


3
Heinrichs David E, Dale Suzanne: Screening assays for inhibitors of a staphylococcus aureus siderophore. Univ Western Ontario, May 23, 2007: EP1786907-A2

The present invention relates to the discovery of the role ofStaphylococcus aureus (S. aureus) sbn operon in the biosynthesis of a novel siderophore. The invention further relates to methods for screening compounds that inhibit the biosynthesis of the siderophore.


4
Heinrichs David E, Dale Suzanne: Bacterial iron acquisition targets. Univ Western Ontario, May 16, 2007: EP1784220-A2

Screening methods for identifying compounds that inhibit the SirABC ironsiderophore transport system.


5
Heinrichs David E, Dale Suzanne: Screening assays for inhibitors of a staphylococcus aureus siderophore. The University Of Western Ontario, August 24, 2007: KR1020077007982

The present invention relates to the discovery of the role of Staphylococcus aureus (S. aureus) sbn operon in the biosynthesis of a novel siderophore. The invention further relates to methods for screening compounds that inhibit the biosynthesis of the siderophore.


6
Heinrichs David E, Dale Suzanne: Bacterial iron acquisition targets. The University Of Western Ontario, June 7, 2007: KR1020077006817

Screening methods for identifying compounds that inhibit the SirABC ironsiderophore transport system.


7
DALE SUZANNE, HEINRICHS DAVID E: COMPOSITIONS PHARMACEUTIQUES RENFERMANT DES INHIBITEURS DE TRANSPORT DU FER ET METHODE DIDENTIFICATION DES INHIBITEURS DE TRANSPORT DU FER CHEZ LE STAPHYLOCOCCUS AUREUS, PHARMACEUTICAL COMPOSITIONS COMPRISING INHIBITORS OF IRON TRANSPORT, AND METHOD OF IDENTIFYING IRON TRANSPORT INHIBITORS, IN STAPHYLOCOCCUS AUREUS. THE UNIVERSITY OF WESTERN ONTARIO, THE UNIVERSITY OF WESTERN ONTARIO, GOWLING WLG, August 30, 2016: CA2576247

Pharmaceutical compositions comprising inhibitors of the SirABC or FhuC iron- siderophore transport system, and their use for treating an infection of Staphylococcus aureus in a subject Screening methods for mdentifymg SirABC or FhuC iron-siderophore transport system inhibitors are also disclosed