1
Dachuan Yang, Joel L Stanslaski, Lixiao Wang, Scott R Smith: Stent coating. SciMed Life Systems, Crompton Seager & Tufte, July 10, 2001: US06258121 (455 worldwide citation)

A stent having a polymeric coating for controllably releasing an included active agent. The polymeric coating includes a blend of a first polymeric material, which if alone, would release the agent at a first, higher rate, and a second polymeric material, which if alone would release the agent at a ...


2
Dachuan Yang, Carmen Jacob, Lixiao Wang: Surface treatment method for stent coating. SciMed Life Systems, Crompton Seager & Tufte, September 19, 2000: US06120847 (243 worldwide citation)

A method is provided for eliminating surface imperfections on a medical device having a drug release coating including a therapeutic substance in a polymeric carrier disposed on at least a portion of the medical device. The medical device is preferably a stent including wire-like members interconnec ...


3
Gholam A Peyman, Dachuan Yang, Bahram Khoobehi: Biodegradable porous device for long-term drug delivery with constant rate release and method of making the same. Board of Supervisors of Louisiana State University, Agricultural and Mechanical College, Haverstock Garrett & Roberts, May 14, 1996: US05516522 (204 worldwide citation)

A biodegradable porous drug delivery device for controllably releasing a pharmacological agent is disclosed which comprises a hollow tube closed at both ends having an interior surface and an exterior surface, the tube formed of a mixture of polycaprolactone and a pore-creating agent, the tube furth ...


4
Dachuan Yang, Lixiao Wang, Joel Stanslaski, Liguang Tang: Hydrophilic lubricity coating for medical devices comprising a hydrophobic top coat. Scimed Life Systems, Vidas Arrett & Steinkraus, January 23, 2001: US06176849 (164 worldwide citation)

The present invention relates to a medical device for insertion into the body wherein the device has at least one surface which periodically comes into contact with a second surface. The first surface comprises an improved lubricious coating having a first hydrogel layer and a second hydrophobic top ...


5
Dachuan Yang, Jaydeep Y Kokate: Method and apparatus for treating septal defects. SciMed Life Systems, Crompton Seager & Tufte, July 22, 2003: US06596013 (155 worldwide citation)

Systems and methods for treating septal defects. A system for treating septal defects may comprise a first catheter having a distal end and a first lumen, a second catheter having a distal end a second lumen, a bridge member extending between the distal end of the first catheter and the distal end o ...


6
Lixiao Wang, Dachuan Yang, John Jianhua Chen, Yiqun Bruce Wang, Lance A Monroe, Joel R Munsinger: Hydrophilic lubricant coatings for medical devices. SciMed Life Systems, Vidas Arrett & Steinkraus P A, October 1, 2002: US06458867 (82 worldwide citation)

The present invention relates to a medical device comprising at least one tubular member having an inner surface and an outer surface. The inner surface of the tubular member is at least occasionally subjected to contact with at least one second surface. The tubular member therefore comprises a hydr ...


7
Lixiao Wang, Yiqun Wang, Dachuan Yang: Method of coating polymeric tubes used in medical devices. SciMed Life Systems, Vidas Arrett & Steinkraus P A, September 10, 2002: US06447835 (79 worldwide citation)

The present invention relates to a method of preparing a coated hollow polymeric tubular member useful in medical devices. The method involves a simple, unique method of simultaneously extruding and coating the polymeric tube.


8
Roger N Hastings, Lixiao Wang, Dachuan Yang, Mark T Ungs, Michael J Urick: Local application of oxidizing agents to prevent restenosis. SciMed Life Systems, Crompton Seager & Tufte, September 14, 1999: US05951458 (74 worldwide citation)

A method for inhibiting restenosis including local application of an oxidizing agent to blood vessel walls. Preferred oxidizing agents include peroxides, most preferably hydrogen peroxide. Oxidizing agents can be delivered utilizing drug delivery balloon catheters. Preferred delivery catheters inclu ...


9
Dachuan Yang, Scott L Sjoquist, Jan D Seppala: Lubricated catheter balloon. SciMed Life Systems, Vidas Arrett & Steinkraus P A, September 3, 2002: US06444324 (74 worldwide citation)

A dilatation balloon comprising an inner surface and an outer surface, the inner surface having a lubricious material disposed thereon to reduce friction or prevent adherence of adjacent layers, and thus reduce the pressure required for inflation.


10
Dachuan Yang, Lixiao Wang, Joel Stanslaski, Liguang Tang: Hydrophilic lubricity coating for medical devices comprising a hybrid top coat. SciMed Life Systems, Vidas Arrett & Steinkraus, August 26, 2003: US06610035 (68 worldwide citation)

The present invention relates to a medical device for insertion into the body wherein the device has at least one surface which periodically comes into contact with a second surface. The first surface comprises an improved lubricious coating having a first hydrogel layer and a second hydrophobic top ...