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Woolf Clifford, D Urso Donatella, Befort Katia, Costigan Michael: Nucleic acid and amino acid sequences involved in pain. The General Hospital Corporation, Bayer, Woolf Clifford, D Urso Donatella, Befort Katia, Costigan Michael, WILLIAMS Kathleen Madden, February 27, 2003: WO/2003/016475 (7 worldwide citation)

The present invention relates to nucleic acid sequences which are related to pain and which are differentially expressed during pain. The invention further relates to methods of identifying nucleic acid sequences which are differentially expressed during pain, microarrays comprising such differentia ...


2
Golz Stefan, Summer Holger, Geerts Andreas, Brüggemeier Ulf, Albrecht Küpper Barbara, Klein Martina, Steppan Sonja, Ellinghaus Peter, D Urso Donatella, Seewald Michael, Milting Hendrik: Ltbp2 as a biomarker, therapeutic and diagnostic target. Bayer Healthcare, Golz Stefan, Summer Holger, Geerts Andreas, Brüggemeier Ulf, Albrecht Küpper Barbara, Klein Martina, Steppan Sonja, Ellinghaus Peter, D Urso Donatella, Seewald Michael, Milting Hendrik, BAYER HEALTHCARE, April 24, 2008: WO/2008/046509 (5 worldwide citation)

The invention provides LTBP2 which is associated with the cardiovascular diseases, hematological diseases, neurological diseases, cancer, endocrinological diseases and urological diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of ...


3
Betz Ulrich, D Urso Donatella, Gatsios Petros, Seewald Michael, Strayle Jochen, Van Es Helmuth Hendrikus Gerardus, Van, Zutphen Marlijn, Mesic Emir: Novel targets and compounds useful in the treatment and/or prophylaxis of a cardiovascular disorder, dyslipidemia and atherosclerosis, and methods to identify such compounds. Galapagos, Betz Ulrich, D Urso Donatella, Gatsios Petros, Seewald Michael, Strayle Jochen, Van Es Helmuth Hendrikus Gerardus, Van, Zutphen Marlijn, Mesic Emir, MANTEN Annemieke, January 4, 2007: WO/2007/000292 (1 worldwide citation)

The present invention provides targets and methods for the screening for compounds useful in the prevention, amelioration or treatment and/or prophylaxis of a cardiovascular disorder, dyslipidemia, and/or Atherosclerosis. The invention also relates to the targets that were identified. Inhibiting or ...


4
D Urso Donatella, Kalthof Bernd, Meier Heinrich: (De) Substituierte 4-aryl-pyridine als kiss-1 antagonisten, (En) Substituted 4-aryl pyridines used as kiss-1 antagonists. Bayer Healthcare, D Urso Donatella, Kalthof Bernd, Meier Heinrich, BAYER HEALTHCARE, July 15, 2004: WO/2004/058716 (1 worldwide citation)

(EN) The invention relates to novel 4-aryl pyridines of formula (I), in which R1 - R4 are defined as cited in claim 1, to methods for producing the same and to the use of said pyridines for the treatment and/or prophylaxis of diseases, in addition to their use for producing medicaments for the treat ...


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Betz Ulrich, D Urso Donatella, Kolkhof Peter, Seewald Michael, Strayle Jochen, Grabner Anne, Hannus Michael: Human marker genes and agents for cardiovascular disorders and artherosclerosis. Cenix Bioscience, Betz Ulrich, D Urso Donatella, Kolkhof Peter, Seewald Michael, Strayle Jochen, Grabner Anne, Hannus Michael, October 19, 2006: WO/2006/108584 (1 worldwide citation)

The invention relates to novel targets in the screening for compounds useful in the treatment and/or prophylaxis of a disease selected from the group comprising cardiovascular diseases, disorders of lipid metabolism or atherosclerosis. The invention relates to novel compounds for use as a medicament ...


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Golz Stefan, Summer Holger, Geerts Andreas, Brueggemeier Ulf, Albrecht Kuepper Barbara, Klein Martina, Steppan Sonja, Ellinghaus Peter, D Urso Donatella, Seewald Michael, Milting Hendrik: Ctgf as a biomarker, therapeutic and diagnostic target. Bayer Schering Pharma, July 1, 2009: EP2074429-A1

The invention provides CTGF which is associated with the cardiovascular diseases and hematological diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases and hematological diseases. The invention also features ...


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Betz Ulrich, D Urso Donatella, Kolkhof Peter, Seewald Michael, Strayle Jochen, Plotner Anne, Hannus Michael: Human marker genes and agents for diagnosis, treatment and prophylaxis of cardiovascular disorders and artherosclerosis. Cenix Bioscience, January 16, 2008: EP1877798-A2

The invention relates to novel targets in the screening for compounds useful in the treatment and/or prophylaxis of a disease selected from the group comprising cardiovascular diseases, disorders of lipid metabolism or atherosclerosis. The invention relates to novel compounds for use as a medicament ...


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Woolf Clifford, D Urso Donatella, Befort Katia, Costigan Michael: Nucleic acid and amino acid sequences involved in pain. Gen Hospital, Bayer, November 24, 2004: EP1478772-A2

The present invention relates to nucleic acid sequences which are related to pain and which are differentially expressed during pain. The invention further relates to methods of identifying nucleic acid sequences which are differentially expressed during pain, microarrays comprising such differentia ...


9
Woolf Clifford, D Urso Donatella, Costigan Michael: Nucleic acid and amino acid sequences involved in pain. The General Hospital Corporation, Woolf Clifford, D Urso Donatella, Costigan Michael, WILLIAMS Kathleen M, July 7, 2005: WO/2005/060667

The present invention relates to nucleic acid sequences which are related to pain and which are differentially expressed during pain. The invention further relates to methods of identifying nucleic acid sequences which are differentially expressed during pain, microarrays comprising such diffrential ...


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