1
D Lansing Taylor: Miniaturized cell array methods and apparatus for cell-based screening. Cellomics, David S Harper, McDonnell Boehnen Hulbert & Berghoff, August 15, 2000: US06103479 (228 worldwide citation)

The present invention discloses devices and methods of performing high throughput screening of the physiological response of cells to biologically active compounds and methods of combining high-throughput with high-content spatial information at the cellular and subcellular level as well as temporal ...


2
R Terry Dunlay, D Lansing Taylor: System for cell-based screening. Cellomics, David S McDonnell Boehnen Hulbert & Berghoff Harper, November 23, 1999: US05989835 (222 worldwide citation)

The invention relates to an optical system for determining the distribution, environment, or activity of fluorescently labeled reporter molecules in cells for the purpose of screening large numbers of compounds for specific biological activity. The invention involves providing cells containing fluor ...


3
R Terry Dunlay, D Lansing Taylor, Albert H Gough, Kenneth A Giuliano: System for cell-based screening. Cellomics, McDonnell Boehnen Hulbert & Berghoff, April 27, 2004: US06727071 (84 worldwide citation)

The present invention provides systems, methods, and screens for an optical system analysis of cells to rapidly determine the distribution, environment, or activity of fluorescently labeled reporter molecules in cells for the purpose of screening large numbers of compounds for those that specificall ...


4
R Terry Dunlay, D Lansing Taylor: System for cell-based screening. Cellomics, David S Harper, McDonnell Boehnen Hulbert & Berghoff, September 16, 2003: US06620591 (79 worldwide citation)

The invention relates to an optical system for determining the distribution, environment, or activity of fluorescently labeled reporter molecules in cells for the purpose of screening large numbers of compounds for specific biological activity. The invention involves providing cells containing fluor ...


5
R Terry Dunlay, D Lansing Taylor, Albert H Gough, Kenneth A Giuliano: Machine readable storage media for detecting distribution of macromolecules between nucleus and cytoplasm in cells. Cellomics, David S Harper, McDonnell Boehnen Hulbert & Berghoff, December 30, 2003: US06671624 (58 worldwide citation)

The present invention provides systems, methods, and screens for an optical system analysis of cells to rapidly determine the distribution, environment, or activity of fluorescently labeled reporter molecules in cells for the purpose of screening large numbers of compounds for those that specificall ...


6
R Terry Dunlay, D Lansing Taylor: System for cell-based screening. Cellomics, David S Harper, McDonnell Boehnen Hulbert & Berghoff, June 3, 2003: US06573039 (40 worldwide citation)

The invention relates to an optical system for determining the distribution, environment, or activity of fluorescently labeled reporter molecules in cells for the purpose of screening large numbers of compounds for specific biological activity. The invention involves providing cells containing fluor ...


7
Frederick Lanni, D Lansing Taylor, Brent Bailey: Field synthesis and optical subsectioning for standing wave microscopy. Carnegie Mellon University, Kirkpatrick & Lockhart, April 25, 2000: US06055097 (36 worldwide citation)

In an improved optical microscope for observing a luminescent specimen, the specimen is excited by a single, on axis standing wavefield or multiple superposed series of standing wave fields. Then an image of the specimen is recorded and displayed. This specimen can be incrementally moved and additio ...


8
Frederick Lanni, D Lansing Taylor, Alan S Waggoner: Standing wave luminescence microscopy. Carnegie Mellon University, Buell Ziesenheim Beck & Alstadt, November 11, 1986: US04621911 (34 worldwide citation)

An optical microscope and a method are described wherein a luminescent specimen is located in, and illuminated by, a nodal standing wave field. Luminescence (fluorescence or phosphorescence) is excited in a series of parallel equispaced laminar antinodal zones separated by a series of dark nodal zon ...


9
R Terry Dunlay, D Lansing Taylor, Albert H Gough, Kenneth A Giuliano: Machine-readable storage medium for analyzing distribution of macromolecules between the cell membrane and the cell cytoplasm. Cellomics, McDonnell Boehnen Hulbert & Berghoff, October 3, 2006: US07117098 (27 worldwide citation)

The present invention provides systems, methods, and screens for an optical system analysis of cells to rapidly determine the distribution, environment, or activity of fluorescently labeled reporter molecules in cells for the purpose of screening large numbers of compounds for those that specificall ...


10
Frederick Lanni, D Lansing Taylor, Brent Bailey: Field synthesis and optical subsectioning for standing wave microscopy. Carnegie Mellon University, Kirkpatrick & Lockhart, September 1, 1998: US05801881 (27 worldwide citation)

In an improved optical microscope for observing a luminescent specimen, the specimen is excited by a single, on axis or multiple superposed series of standing wave fields. Then an image of the specimen is recorded and displayed. This specimen can be incrementally moved and additional images can be r ...