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Gale E Smith, Franklin Volvovitz, Bethanie E Wilkinson, Andrei I Voznesensky, Craig S Hackett: Vaccine comprising a baculovirus produced influenza hemagglutinin protein fused to a second protein. Protein Sciences Corporation, Thomas J Kowalski, Frommer Lawrence & Haug, January 12, 1999: US05858368 (82 worldwide citation)

A method of preparing a recombinant influenza vaccine using DNA technology is provided. The resulting vaccine is a multivalent, preferably trivalent, influenza vaccine based on a mixture of recombinant hemagglutinin antigens cloned from influenza viruses having epidemic potential. The recombinant he ...


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Gale E Smith, Franklin Volvovitz, Bethanie E Wilkinson, Andrei I Voznesensky, Craig S Hackett: Method for producing influenza hemagglutinin multivalent vaccines. Protein Sciences Corporation, Thomas J Kowalski, Frommer Lawrence & Haug, June 12, 2001: US06245532 (24 worldwide citation)

A method of preparing a recombinant influenza vaccine using DNA technology is provided. The resulting vaccine is a multivalent, preferably trivalent, influenza vaccine based on a mixture of recombinant hemagglutinin antigens cloned from influenza viruses having epidemic potential. The recombinant he ...


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Gail Eugene Smith, James T Matthews, Edwin D Kilbourne, Bert E Johansson, Bethanie E Wilkinson, Andrei I Voznesensky, Craig S Hackett, Franklin Volvovitz: Neuraminidase-supplemented compositions. Protein Sciences Corporation, William S Frommer, Thomas J Kowalski, Frommer Lawrence & Haug, November 26, 2002: US06485729 (11 worldwide citation)

An anti-influenza vaccine composition wherein the improvement is that the vaccine includes, as an additive, neuraminidase (NA). The base anti-influenza vaccine can be any commercially available anti-influenza vaccine. The composition can include and be administered with an adjuvant. The vaccine comp ...


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Gail Eugene Smith, James T Matthews, Edwin D Kilbourne, Bert E Johansson, Bethanie E Wilkinson, Andrie I Voznesensky, Craig S Hackett, Franklin Volvovitz: Methods of making neuraminidase-supplemented compositions. Protein Sciences Corporation, Frommer Lawrence & Haug, Thomas J Kowalski, Angela M Collison, October 4, 2005: US06951649 (4 worldwide citation)

The present invention relates to a method for formulating a vaccine composition which comprises an anti-influenza vaccine, wherein the improvement of the vaccine composition is that the vaccine includes, as an additive, neuraminidase (NA). The base anti-influenza vaccine can be any commercially avai ...


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Gale Eugene Smith, James T Matthews, Edwin D Kilbourne, Bert E Johansson, Bethanie E Wilkinson, Andrei I Voznesensky, Craig S Hackett, Franklin Volvovitz: Neuraminidase-supplemented compositions. Frommer Lawrence & Haug, September 4, 2003: US20030165521-A1

An anti-influenza vaccine composition wherein the improvement is that the vaccine includes, as an additive, neuraminidase (NA). The base anti-influenza vaccine can be any commercially available anti-influenza vaccine. The composition can include and be administered with an adjuvant. The vaccine comp ...


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Gale Eugene Smith, Bethanie E Wilkinson, Andrei I Voznesensky, Franklin Volvovitz, Craig S Hackett: Virus vaccines. Frommer Lawrence & Haug, June 13, 2002: US20020071848-A1

Improved mammalian virus vaccines are combinations that contain an immunogenic amount of inactivated virus, such as influenza virus, Herpes varicella virus, measles virus, Epstein Barr virus, respiratory syncytial virus, parainfluenza 3, Herpes simplex type 1 virus, and Herpes simplex type 2 virus, ...


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