1
Brian L Goodall, Alex M Aravanis, Craig A Behnke, Richard J Cranford, Daniel J Sajkowski: Methods of preparing oil compositions for fuel refining. SAPPHIRE ENERGY, Sapphire Energy, September 29, 2015: US09145528

Disclosed herein are methods and systems for upgrading (for example, removing heteroatoms, metals, or metalloids) an oil composition derived or extracted from a biomass. The upgraded oil composition can be used to make a desired product, for example, a fuel product.


2
Michael Mendez, Craig A Behnke, Nicole A Heaps: Variant isoprenoid producing enzymes and uses thereof. Sapphire Energy, Sapphire Energy, March 24, 2015: US08987433

This disclosure provides methods of designing and generating polypeptide variants that have altered properties compared to a parent polypeptide. The present disclosure provides methods of generating polypeptide variants, for example, variant isoprenoid synthases and/or variant prenyl transferases th ...


3
Craig A Behnke, David Molina, Soyan Lieberman, Jamie Bacher, Shuiqin Wu: Acetyl CoA carboxylases. SAPPHIRE ENERGY, Sapphire Energy, September 15, 2015: US09133489

Provided herein are novel ACCases and nucleotides encoding the same, that when introduced into a cell or organism results in an increase and/or accumulation of fatty acids, glycerol lipids, and/or oils in the cell or organism, and/or a change in the types of fatty acids, glycerol lipids, and/or oils ...


4
Christopher Yohn, April Brand, Michael Mendez, Craig A Behnke: Transformation of algae for increasing lipid production. SAPPHIRE ENERGY, Sapphire Energy, August 30, 2016: US09428779

The present disclosure provides novel proteins that when over expressed in algae result in an increase or change in fatty acid and/or glycerol lipid production and/or accumulation, without a substantial decrease in the growth rate of the alga or the break down of algal components, such as chlorophyl ...


5
Masashi Miyano, Takashi Kumasaka, Tetsuya Hori, Hiroyuki Motoshima, Tetsuji Okada, Masaki Yamamoto, Krzysztof Palczewski, Craig A Behnke, Brian A Fox, Isolde Le Trong, David C Teller, Ronald E Stenkamp: Three-dimensional structure of bovine rhodopsin. Fish & Richardson PC, October 3, 2002: US20020142385-A1

The present invention discloses a three-dimensional structure of bovine rhodopsin. There is provided a G protein-coupled receptor selected from the group consisting of the following (a) and (b): (a) a G protein-coupled receptor having three-dimensional structure I defined by the atomic coordinates a ...


6
Craig A Behnke, David Molina, Soyan Lieberman, Jamie Bacher, Shuiqin Wu: NOVEL ACETYL CoA CARBOXYLASES. Sapphire Energy, September 13, 2012: US20120231546-A1

Provided herein are novel ACCases and nucleotides encoding the same, that when introduced into a cell or organism results in an increase and/or accumulation of fatty acids, glycerol lipids, and/or oils in the cell or organism, and/or a change in the types of fatty acids, glycerol lipids, and/or oils ...


7
Nicole A Heaps, Craig A Behnke, David Molina: Biofuel production in prokaryotes and eukaryotes. Sapphire Energy, March 8, 2012: US20120058535-A1

Terpene synthases are enzymes that directly convert IPP & DMAPP to terpenes, such as fusicoccadiene. Described herein are methods and compositions for the production of terpenes and terpenoids for use as fuel molecules or other useful components. Genetically engineered enzymes capable of producing t ...


8
Michael Mendez, Craig A Behnke, Nicole A Heaps: Variant isoprenoid producing enzymes and uses thereof. Shapphire Energy, March 15, 2012: US20120064629-A1

This disclosure provides methods of designing and generating polypeptide variants that have altered properties compared to a parent polypeptide. The present disclosure provides methods of generating polypeptide variants, for example, variant isoprenoid synthases and/or variant prenyl transferases th ...


9
Christopher Yohn, April Brand, Michael Mendez, Craig A Behnke: Stress-induced lipid trigger. Sapphire Energy, December 20, 2012: US20120322157-A1

The present disclosure provides novel proteins that when over expressed in algae result in an increase or change in fatty acid and/or glycerol lipid production and/or accumulation, without a substantial decrease in the growth rate of the alga or the break down of algal components, such as chlorophyl ...


10
Beth A Rasala, Rosa M F Cardoso, Machiko Muto, Stephen P Mayfield, Philip A Lee, Craig A Behnke, Michael Mendez: Production of Therapeutic Proteins in Photosynthetic Organisms. The Scripps Research Institute, Sapphire Energy, December 6, 2012: US20120309939-A1

The present disclosure relates to methods of expressing therapeutic proteins in photosynthetic organisms and the therapeutic proteins produced by the methods. The therapeutic proteins include high-mobility group box 1 (HMGB1) protein, fibronectin domain (10) (10FN3), fibronectin domain (14) (14FN3), ...