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D Aoust Marc André, Couture Manon, Ors Frédéric, Trepanier Sonia, Lavoie Pierre Olivier, Dargis Michèle, Vezina Louis Philippe, Landry Nathalie: (vlps) Comprising hemagglutinin produced within a plant. Medicago, D Aoust Marc André, Couture Manon, Ors Frédéric, Trepanier Sonia, Lavoie Pierre Olivier, Dargis Michèle, Vezina Louis Philippe, Landry Nathalie, SECHLEY Konrad A, January 22, 2009: WO/2009/009876 (11 worldwide citation)

A method for synthesizing influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of influenza HA in plants and the purification by size exclusion chromatography. The invention is also directed towards a VLP comprising influenza HA pro ...


2
D Aoust Marc Andre, Couture Manon, Ors Frédéric, Trepanier Sonia, Lavoie Pierre Olivier, Dargis Michèle, Vezina Louis Philippe, Landry Nathalie: Influenza virus-like particles (vlps) comprising hemagglutinin. Medicago, D Aoust Marc Andre, Couture Manon, Ors Frédéric, Trepanier Sonia, Lavoie Pierre Olivier, Dargis Michèle, Vezina Louis Philippe, Landry Nathalie, Sechley Konrad A, January 14, 2010: WO/2010/003225 (7 worldwide citation)

A method for synthesizing influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of influenza HA of type A/California/04/09 in plants and the purification by size exclusion chromatography. The invention is also directed towards a VLP ...


3
COUTURE MANON: Chimeric influenza virus-like particles comprising hemagglutinin. MEDICAGO, Sechley Konrad A, December 29, 2010: WO/2010/148511 (7 worldwide citation)

A method for synthesizing chimeric influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of chimeric influenza HA in a plant or a portion of a plant. The invention is also directed towards a VLP comprising chimeric influenza HA prote ...


4
D Aoust Marc André, Couture Manon, Ors Frédéric, Trépanier Sonia, Lavoie Pierre Olivier, Dargis Michèle, Vézina Louis Philippe, Landry Nathalie: (vlps) Produced in transgenic plants expressing hemagglutinin. Medicago, D Aoust Marc André, Couture Manon, Ors Frédéric, Trépanier Sonia, Lavoie Pierre Olivier, Dargis Michèle, Vézina Louis Philippe, Landry Nathalie, SECHLEY Konrad A, June 25, 2009: WO/2009/076778 (5 worldwide citation)

A method for synthesizing influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of influenza HA in plants and the purification by size exclusion chromatography. The invention is also directed towards a VLP comprising influenza HA pro ...


5
D AOUST MARC ANDRE, COUTURE MANON, ORS FREDERIC, TREPANIER SONIA, LAVOIE PIERRE OLIVIER, DARGIS MICHELE, VEZINA LOUIS PHILIPPE, LANDRY NATHALIE: PSEUDO-PARTICULES DU VIRUS DE LA GRIPPE (VLP) COMPRENANT DE LHEMAGGLUTININE (HA) PRODUIT DANS UNE PLANTE, INFLUENZA VIRUS-LIKE PARTICLES (VLPS) COMPRISING HEMAGGLUTININ PRODUCED WITHIN A PLANT. MEDICAGO, MEDICAGO, GOWLING LAFLEUR HENDERSON, September 24, 2013: CA2693956 (4 worldwide citation)

A method for synthesizing influenza virus--like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of influenza HA in plants and the purification by size exclusion chromatography. The invention is also directed towards a VLP comprising influenza HA pr ...


6
D AOUST MARC ANDRE, COUTURE MANON, ORS FREDERIC, TREPANIER SONIA, DARGIS MICHELE, VEZINA LOUIS PHILIPPE, LANDRY NATHALIE, LAVOIE PIERRE OLIVIER: PARTICULES PSEUDOVIRALES (VLP) DE LA GRIPPE RECOMBINEES PRODUITES DANS DES PLANTES TRANSGENIQUES EXPRIMANT LHEMAGGLUTININE, RECOMBINANT INFLUENZA VIRUS-LIKE PARTICLES (VLPS) PRODUCED IN TRANSGENIC PLANTS EXPRESSING HEMAGGLUTININ. MEDICAGO, MEDICAGO, GOWLING LAFLEUR HENDERSON, November 19, 2013: CA2707235 (4 worldwide citation)

A method for synthesizing influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of influenza HA in plants and the purification by size exclusion chromatography. The invention is also directed towards a VLP comprising influenza HA pro ...


7
Couture Manon, Vézina Louis Philippe, Landry Nathalie: New influenza virus immunizing epitope. Medicago, Couture Manon, Vézina Louis Philippe, Landry Nathalie, Ogilvy Renault Sencrl, January 21, 2010: WO/2010/006452 (4 worldwide citation)

A method for synthesizing influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of a novel influenza HA protein in plants and its purification The invention is also directed towards a VLP comprising influenza HA protein and plants li ...


8
D AOUST Marc Andre, COUTURE Manon, LAVOIE Pierre Olivier, VEZINA Louis Philippe: PRODUCTION DE PARTICULES DE TYPE VIRAL CHEZ DES VÉGÉTAUX, VIRUS LIKE PARTICLE PRODUCTION IN PLANTS. MEDICAGO, D AOUST Marc Andre, COUTURE Manon, LAVOIE Pierre Olivier, VEZINA Louis Philippe, SECHLEY Konrad A, June 28, 2012: WO/2012/083445 (3 worldwide citation)

A method of producing a virus like particle (VLP) in a plant, and compositions comprising VLPs, are provided. The method involves introducing a nucleic acid comprising a regulatory region active in the plant and operatively linked to a chimeric nucleotide sequence encoding, in series, an ectodomain ...


9
Couture Manon, Landry Nathalie, Vezina Louis Philippe, Dargis Michèle: Soluble recombinant influenza antigens. Medicago, Couture Manon, Landry Nathalie, Vezina Louis Philippe, Dargis Michèle, Sechley Konrad A, January 14, 2010: WO/2010/003235 (3 worldwide citation)

The present invention provides a recombinant soluble trimeric hemagglutinin (rHA) protein comprising a hemagglutinin ectodomain and an oligomerization domain. The rHA is produced as a soluble homotrimer, and may further comprises a signal peptide and/or an endoplasmic reticulum (ER) retention signal ...


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COUTURE MANON , DARGIS MICHELE , LAVOIE PIERRE OLIVIER , VEZINA LOUIS PHILIPPE , D AOUST MARC ANDRE : [de] CHIMÄRISCHE INFLUENZA-VIRUS-ÄHNLICHE PARTIKEL MIT HÄMAGGLUTININ, [en] CHIMERIC INFLUENZA VIRUS- LIKE PARTICLES COMPRISING HEMAGGLUTININ, [fr] PARTICULES DE TYPE VIRUS DE LA GRIPPE CHIMÉRIQUES COMPORTANT DE LHÉMAGGLUTININE. MEDICAGO  , October 11, 2017: EP3228627-A1

[en] A method for synthesizing chimeric influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of chimeric influenza HA in a plant or a portion of a plant. The invention is also directed towards a VLP comprising chimeric influenza HA ...