1
Corey H Levenson, Kary B Mullis: Precursor to nucleic acid probe. Cetus Corporation, Albert P Halluin, Janet E Hasak, June 28, 1988: US04754065 (186 worldwide citation)

Nucleic acids may be labeled by intercalating the alkylating intercalation moiety of a labeling reagent into a partially double-stranded nucleic acid to form a complex and activating the complex to cause covalent bonding between the reagent and the nucleic acid. Preferably, the labeled nucleic acid ...


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Edward L Sheldon III, Corey H Levenson, Kary B Mullis, Henry Rapoport, Robert M Watson: Process for labeling nucleic acids and hybridization probes. Cetus Corporation, Albert P Halluin, Janet E Hasak, October 14, 1986: US04617261 (48 worldwide citation)

Nucleic acids may be labeled by intercalating the alkylating intercalation moiety of a labeling reagent into a partially double-stranded nucleic acid to form a complex and activating the complex to cause covalent bonding between the reagent and the nucleic acid. Preferably, the labeled nucleic acid ...


4
John B Findlay, Janice M Mayer, Marlene M King, Fred T Oakes, Chu an Chang, Corey H Levenson: Nucleic acid test article and its use to detect a predetermined nucleic acid. Johnson & Johnson Clinical Diagnostics, May 7, 1996: US05514550 (46 worldwide citation)

A nucleic acid test article can be used to detect a targeted nucleic acid found in a specimen. The test article includes a substrate having two opposing surfaces and a water-insoluble nucleic acid probe attached in a distinct zone of one of the surfaces. The probe is prepared from a water-insoluble ...


5
Corey H Levenson, Kary B Mullis: Precursor to nucleic acid probe. Cetus Corporation, Janet E Hasak, Albert P Halluin, November 10, 1987: US04705886 (14 worldwide citation)

Nucleic acids may be labeled by intercalating the alkylating intercalation moiety of a labeling reagent into a partially double-stranded nucleic acid to form a complex and activating the complex to cause covalent bonding between the reagent and the nucleic acid. Preferably, the labeled nucleic acid ...


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Corey H Levenson, Kary B Mullis: Precursor to nucleic acid probe. Cetus Corporation, Albert P Halluin, Janet E Hasak, June 14, 1988: US04751313 (8 worldwide citation)

Nucleic acids may be labeled by intercalating the alkylating intercalation moiety of a labeling reagent into a partially double-stranded nucleic acid to form a complex and activating the complex to cause covalent bonding between the reagent and the nucleic acid. Preferably, the labeled nucleic acid ...


7
Corey H Levenson, Kary B Mullis: Carbamic acid ester useful for preparing a nucleic acid probe. Cetus Corporation, Albert P Halluin, Janet E Hasak, February 7, 1989: US04803297 (6 worldwide citation)

Nucleic acids may be labeled by intercalating the alkylating intercalation moiety of a labeling reagent into a partially double-stranded nucleic acid to form a complex and activating the complex to cause covalent bonding between the reagent and the nucleic acid. Preferably, the labeled nucleic acid ...


8
Danute E Nitecki, Margaret Moreland, Lois Aldwin, Corey H Levenson, Irwin Braude, David F Mark, Henry Rapaport: Immunosupressive analogues and derivatives of succinylacetone. Cetus Corporation, Gregory J Giotta, Albert P Halluin, January 23, 1990: US04895872 (4 worldwide citation)

Succinylacetone derived or related medicaments and methods of synthesis of the same are shown wherein the medicaments consists of succinylacetonyl-proline-PEG, succinylacetonyl-NH-PEG, or compounds that have the formula: ##STR1## and that have immunosuppressive activity both in vivo and in vitro bas ...


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Dale G Ando, Corey H Levenson, Irwin Braude: Methods, compounds, and compositions for immunosuppression. Cetus Corporation, Scott R Bortner, Gregory J Giotta, Wean Khing Wong, September 22, 1992: US05149688 (4 worldwide citation)

This invention is in the area of immunology, and specifically relates to immunopharmacology as applied to the development of immunosuppressive compositions and methods of use thereof for treating a wide variety of diseases arising from abnormal or undesirable normal immune responses. Compositions an ...


10
Corey H Levenson: Process for making succinyl acetone. Cetus Oncology Corporation, Philip L McGarrigle, January 4, 1994: US05276180 (2 worldwide citation)

The present invention is a simplified process for making succinyl acetone (SA). The most preferred embodiment is a one step process that reacts levulinic acid, ethyl acetate, and a base to form SA. Generally, a levulinic acid group may be reacted with an alkyl ester and a base to form SA. Optionally ...