1
James Doherty
Clifton J Blankley, Diane H Boschelli, Annette M Doherty, James M Hamby, Sylvester Klutchko, Robert L Panek: Pyrido [2,3-D]pyrimidines for inhibiting protein tyrosine kinase mediated cellular proliferation. Warner Lambert Company, Charles W Ashbrook, April 15, 1997: US05620981 (42 worldwide citation)

6-Aryl pyrido[2,3-d]pyrimidine 7-imines, 7-ones, and 7-thiones are inhibitors of protein tyrosine kinases, and are thus useful in treating cellular proliferation mediated thereby. The compounds are especially useful in treating cancer, atherosclerosis, restenosis, and psoriasis.


2
Clifton J Blankley, John C Hodges, Sylvester Klutchko: Substituted 1,2,3,4-tetahydroisoquinolines with angiotensin II receptor antagonist properties. Warner Lambert Company, Elizabeth M Anderson, September 21, 1993: US05246943 (56 worldwide citation)

This invention relates to novel substituted 1,2,3,4-tetrahydroisoquinolines which are useful in the treatment of vascular restenosis, various disorders of the central nervous system, in the regulation of female reproductive functions, in cognitive enhancement, in atherosclerosis and in treating exce ...


3
Clifton J Blankley, Lawrence R Bennett: 6-Substituted-arylpyrido[2,3-d]pyrimidin-7-amines and derivatives. Warner Lambert Company, Walter Patton, June 2, 1981: US04271164 (9 worldwide citation)

6-Substituted-arylpyrido[2,3-d]pyrimidin-7-amines and derivatives and their pharmaceutically acceptable acid addition salts are useful in the treatment of hypertension.


4
Clifton J Blankley, John C Hodges, Sylvester Klutchko: Substituted 1,2,3,4-tetrahydroisoquinolines with angiotensin II receptor antagonist properties. Warner Lambert Company, Elizabeth M Anderson, June 11, 1996: US05525614 (5 worldwide citation)

This invention relates to novel substituted 1,2,3,4-tetrahydroisoquinolines which are useful in the treatment of vascular restenosis, various disorders of the central nervous system, in the regulation of female reproductive functions, in cognitive enhancement, in atherosclerosis and in treating exce ...


5
Clifton J Blankley, John C Hodges, Sylvester Klutchko: Substituted 1,2,3,4-tetrahydroisoquinolines with angiotensin II receptor antagonist properties. Warner Lambert Company, Elizabeth M Anderson, September 27, 1994: US05350757 (4 worldwide citation)

This invention relates to novel substituted 1,2,3,4-tetrahydroisoquinolines which are useful the treatment of vascular restenosis, various disorders of the central nervous system, in the regulation of female reproductive functions, in cognitive enhancement, in atherosclerosis and in treating excessi ...


6
Clifton J Blankley, John C Hodges, Sylvester Klutchko: Substituted 1,2,3,4-tetrahydroisoquinolines with angiotensin II receptor antagonist properties. Warner Lambert Company, Elizabeth M Anderson, February 6, 1996: US05489686 (3 worldwide citation)

This invention relates to novel substituted 1,2,3,4-tetrahydroisoquinolines which are useful in the treatment of vascular restenosis, various disorders of the central nervous system, in the regulation of female reproductive functions, in cognitive enhancement, in atherosclerosis and in treating exce ...


7
Clifton J Blankley: Substituted acyl derivatives of octahydro-1H-isoindole-1-carboxylic acids. Warner Lambert Company, Joan Thierstein, March 5, 1985: US04503043 (2 worldwide citation)

Substituted acyl derivatives of octahydro-1H-isoindole-1-carboxylic acid compounds and the pharmaceutically acceptable salts thereof are produced by acylating a suitably substituted octahydro-1H-isoindole with a suitably activated substituted carboxylic acid and when desired hydrolyzing the resultin ...



Click the thumbnails below to visualize the patent trend.