1
Stephen delCardayre, Matthew Tobin, Willem P C Stemmer, Jon E Ness, Jeremy Minshull, Phillip Patten, Venkiteswaran Subramanian, Linda Castle, Claus M Krebber, Steven H Bass: Evolution of whole cells and organisms by recursive sequence recombination. Maxygen, Norman J Kruse, Jonathan Alan Quine, The Law Offices of Jonathan Alan Quine, September 11, 2001: US06287862 (91 worldwide citation)

The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/ ...


2
Stephen delCardayre, Matthew Tobin, William P C Stemmer, Jon E Ness, Jeremy Minshull, Phillip Patten, Venkiteswatan Subramanian, Linda Castle, Claus M Krebber, Steve Bass: Evolution of whole cells and organisms by recursive sequence recombination. Maxygen, Norman J Kruse, Jonathan Alan Quine, Law Offices of Jonathan Alan Quine, March 5, 2002: US06352859 (30 worldwide citation)

The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/ ...


3
Stephen delCardayre, Matthew Tobin, Willem P C Stemmer, Jon E Ness, Jeremy Minshull, Phillip Patten, Venkiteswatan Subramanian, Linda A Castle, Claus M Krebber, Steve Bass, Ying Xin Zhang, Tony Cox, Gjalt Huisman, Ling Yuan, Joseph A Affholter: Evolution of whole cells and organisms by recursive sequence recombination. Maxygen, Norman J Kruse, Joanne R Petithory, December 12, 2006: US07148054 (27 worldwide citation)

The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/o ...


4
Stephen delCardayre, Matthew B Tobin, Willem P C Stemmer, Jon E Ness, Jeremy S Minshull, Phillip A Patten, Venkiteswatan Mani Subramanian, Linda A Castle, Claus M Krebber, Steven H Bass, Ying Xin Zhang, Anthony R Cox, Gjalt W Huisman, Ling Yuan, Joseph A Affholter: Evolution of whole cells and organisms by recursive sequence recombination. Maxygen, December 8, 2009: US07629170 (22 worldwide citation)

The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/ ...


5
Stephen delCardayre, Matthew Tobin, William P C Stemmer, Jon E Ness, Jeremy Minshull, Phillip Patten, Venkiteswaran Subramanian, Linda Castle, Claus M Krebber, Steve Bass: Evolution of whole cells and organisms by recursive sequence recombination. Maxygen, Norman J Kruse, Jonathan A Quine, Quine IP Law Group, March 4, 2003: US06528311 (21 worldwide citation)

The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/ ...


6
Claus M Krebber: Method for producing polynucleotides with desired properties. Maxygen, Norman J Kruse, Jonathan Alan Quine, Law Offices of Jonathan Alan Quine, January 8, 2002: US06337186 (13 worldwide citation)

The invention provides methods for the production of polynucleotides with a desired property (e.g., conferring a desired phenotype and/or encoding polypeptide with a desired property) which is selectable or can be screened for. The method includes making insertions and/or deletions at random sites i ...


7
Stephen DelCardayre, Matthew B Tobin, Willem P C Stemmer, Jon E Ness, Jeremy S Minshull, Phillip A Patten, Venkiteswatan Mani Subramanian, Linda A Castle, Claus M Krebber, Steven H Bass, Ying Xin Zhang, Anthony R Cox, Gjalt W Huisman, Ling Yuan, Joseph A Affholter: Evolution of whole cells and organisms by recursive sequence recombination. Codexis Mayflower Holdings, December 13, 2011: US08076138

The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/ ...


8
Stephen DelCardayre, Matthew B Tobin, Willem P C Stemmer, Jon E Ness, Jeremy S Minshull, Phillip A Patten, Venkiteswatan Mani Subramanian, Linda A Castle, Claus M Krebber, Steven H Bass, Ying Xin Zhang, Anthony R Cox, Gjalt W Huisman, Ling Yuan, Joseph A Affholter: Evolution of whole cells and organisms by recursive sequence recombination. Codexis Mayflower Holdings, Codexis Mayflower Holdings, February 19, 2013: US08377681

The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/ ...


9
Kaman Chan, Fernando Valle, Yoram Barak, Louis Clark, Kristian Karlshoej, Jonathan Vroom, Jovana Nazor, Claus M Krebber, Kenneth Mitchell: Production of fatty alcohols from engineered microorganisms. Codexis, Codexis, July 25, 2017: US09714437

The invention generally relates to the production of a fatty alcohol composition from recombinant microbial cells. The fatty alcohols are produced by expressing a gene encoding a heterologous fatty alcohol forming acyl-CoA reductase (“FAR”); a gene encoding a heterologous thioesterase (“TE”) gene an ...


10
Stephen del Cardayre, Matthew Tobin, Willem PC Stemmer, Jon E Ness, Jeremy Minshull, Phillip Patten, Venkiteswaran Subramanian, Linda A Castle, Claus M Krebber, Steven H Bass, Ying Xin Zhang, Tony Cox, Gjalt Huisman, Ling Yuan, Joseph A Affholter: Evolution of whole cells and organisms by recursive sequence recombination. Maxygen, Maxygen, February 1, 2007: US20070026446-A1

The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/ ...